Glycinorm 80 Tab

GLYCINORM 80 TAB

GLYCINORM 80 TAB, manufactured by IPCA Laboratories Ltd., is an oral anti-diabetic medication used for the management of Type 2 Diabetes Mellitus.

Composition The primary active ingredient in GLYCINORM 80 TAB is Gliclazide, at a strength of 80 mg. Gliclazide belongs to the sulfonylurea class of medicines, which works by stimulating the beta-cells in the pancreas to release more insulin, thereby lowering blood sugar levels. It also helps the body use insulin more effectively and may enhance tissue sensitivity to insulin.

Uses GLYCINORM 80 TAB is prescribed for adults with Type 2 Diabetes Mellitus when diet and exercise alone are insufficient to control blood sugar levels. It helps to:

• Control blood sugar levels.
• Reduce the risk of long-term diabetes complications such as eyesight loss (retinopathy), kidney damage (nephropathy), nerve damage (neuropathy), and diabetic foot ulcer.
• Improve overall metabolic health and energy levels in diabetic individuals.

Dosage and Administration GLYCINORM 80 TAB should be taken orally as directed by a healthcare professional.

• Typical Guidance: An initial adult dose typically ranges from 40 to 80 mg once daily. The dose may be adjusted by the doctor, potentially increasing up to 320 mg daily, based on the individual's condition and response to treatment.
• Administration: It is generally recommended to take the tablet with food, preferably 30 minutes before breakfast, to avoid an upset stomach. The tablet should be swallowed whole with water and not crushed, chewed, or broken.

Side Effects

• Common Side Effects: Hypoglycemia (low blood sugar), which can manifest as sweating, dizziness, headache, shivering, weakness, and confusion; stomach ache or indigestion; nausea; vomiting; constipation; and diarrhea. Some individuals may also experience asthenia (lack of energy) or weight gain.
• Serious Side Effects (less common): Severe side effects may include allergic reactions or abnormalities in liver function. Immediate medical attention should be sought if these occur.

Precautions

• Contraindications: Do not take GLYCINORM 80 TAB if you have Type 1 diabetes, diabetic ketoacidosis, severe liver or kidney disease, diabetic pre-coma or coma, or are allergic to any of its components.
• Alcohol: Avoid alcohol consumption as it can significantly increase the risk of low blood sugar (hypoglycemia).
• Specific Conditions: Caution is advised for patients with a history of heart disease, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or mild to moderate liver or kidney impairment.
• Pregnancy and Breastfeeding: GLYCINORM 80 TAB is generally not recommended during pregnancy and breastfeeding; consult your doctor.
• Driving: As this medicine can cause low blood sugar, which may lead to dizziness or confusion, caution is advised when driving or operating machinery. Always carry a fast-acting source of sugar.
• Interactions: Inform your doctor about all other medicines, including supplements or herbal products, as interactions can occur.
• Monitoring: Regular monitoring of blood sugar levels is crucial while taking this medication. Do not stop taking GLYCINORM 80 TAB without consulting your doctor, even if your blood sugar levels normalize. The safety of this medicine in children has not been established.

Storage Store GLYCINORM 80 TAB in a cool and dry place, protected from direct sunlight and moisture. Keep it out of the sight and reach of children. It should be stored in cool places at 10ºC to 25ºC or below 30ºC.

GLYCINORM 80 TAB contains Gliclazide 80mg, an oral anti-diabetic medication belonging to the sulfonylurea class. It is primarily used to manage type 2 diabetes mellitus in adults.

Here are some frequently asked questions about GLYCINORM 80 TAB:

What is GLYCINORM 80 TAB used for?

GLYCINORM 80 TAB is used to control high blood sugar levels in adults with type 2 diabetes mellitus when diet, exercise, and weight reduction alone are insufficient. Controlling blood sugar helps prevent serious complications of diabetes like nerve damage, kidney problems, heart disease, and blindness.

How does GLYCINORM 80 TAB work?

GLYCINORM 80 TAB works by stimulating the beta-cells in the pancreas to release more insulin. Insulin is a hormone that helps move sugar from the blood into the cells for energy. It also enhances the body's sensitivity to insulin and may help reduce glucose production from the liver.

What is the usual dosage for GLYCINORM 80 TAB?

The usual starting dose for adults is 40 to 80 mg (half or one tablet) once daily, typically taken with breakfast. The dose can be adjusted by your doctor up to a maximum of 320 mg (four tablets) daily. Doses exceeding 160 mg daily are generally taken in two divided doses (morning and evening). It is crucial to always eat a meal after taking the tablet(s).

What are the possible side effects of GLYCINORM 80 TAB?

The most commonly observed side effect is low blood sugar (hypoglycemia), which can manifest as headache, intense hunger, nausea, vomiting, dizziness, weakness, sweating, nervousness, shakiness, or confusion. Other possible side effects include abdominal pain, indigestion, diarrhea, constipation, nausea, vomiting, skin rash or itching, and rarely, liver disorders.

Is GLYCINORM 80 TAB safe during pregnancy or breastfeeding?

GLYCINORM 80 TAB is generally not recommended and is contraindicated during pregnancy and breastfeeding. Insulin is typically the preferred treatment for type 2 diabetes in pregnant women. If you are pregnant, planning a pregnancy, or breastfeeding, discuss this with your doctor.

Can GLYCINORM 80 TAB be taken with other medications?

GLYCINORM 80 TAB can interact with many other medications, which may either increase or decrease its blood sugar-lowering effect. It is important to inform your doctor or pharmacist about all prescription, over-the-counter, herbal remedies, and supplements you are taking. Medications such as other antidiabetics, certain antibiotics (e.g., fluoroquinolones, clarithromycin), antifungals (e.g., miconazole, fluconazole), some blood pressure medications (e.g., beta-blockers, ACE inhibitors), NSAIDs (e.g., ibuprofen, aspirin), and corticosteroids can interact. Alcohol should be avoided as it can increase the risk of low blood sugar and cause an intolerance reaction.

What precautions should be taken while taking GLYCINORM 80 TAB?

It is important to follow your doctor's advice on diet and exercise to minimize the risk of very low blood sugar (hypoglycemia). Do not skip or delay meals. Regularly monitor your blood glucose levels as recommended by your doctor. Inform your doctor if you have liver or kidney problems, G6PD deficiency, or if you become ill with a fever or infection, or are undergoing surgery, as these conditions can affect your blood sugar control. This medication may also make you more sensitive to the sun, so wear protective clothing and use sunscreen.

What happens if a dose of GLYCINORM 80 TAB is missed?

If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

How should GLYCINORM 80 TAB be stored?

GLYCINORM 80 TAB should be stored at room temperature, typically below 25°C or 30°C. Keep it in a secure location, out of the sight and reach of children, and protect it from excessive heat, moisture, or direct sunlight. Dispose of any unused or expired medication safely.