Human Mixtard 50 Injection 40 Iu/ml

HUMAN MIXTARD 50 INJECTION 40 IU/ML by NOVO NORDISK

HUMAN MIXTARD 50 INJECTION 40 IU/ML is a combination insulin product designed to manage blood sugar levels in individuals with diabetes mellitus.

Name

• Brand Name: Human Mixtard 50, Mixtard 50/50
• Common Name: Biphasic Isophane Human Insulin

Composition Each ml of suspension contains 40 International Units (IU) of human insulin. It is a biphasic formulation consisting of 50% soluble human insulin (fast-acting) and 50% isophane insulin (intermediate-acting). Human insulin is produced using recombinant DNA technology.

Uses Human Mixtard 50 is prescribed for the treatment of both Type 1 and Type 2 diabetes mellitus in adults and children. It works by facilitating the uptake of glucose into muscle and fat cells and suppressing glucose production in the liver, thereby improving overall blood sugar control.

Dosage and Administration This medicine is administered via subcutaneous injection (under the skin) in areas like the thigh, abdominal wall, gluteal region, or deltoid region. Injection sites should be rotated to prevent local reactions. It is typically given 15-30 minutes before a meal, usually once or twice daily, as advised by a healthcare professional. Blood glucose monitoring is essential to determine the individual dosage.

Side Effects The most common side effect is hypoglycemia (low blood sugar), which can manifest as lightheadedness, dizziness, anxiety, nervousness, tiredness, hunger, sweating, and shaking. Other potential side effects include injection site reactions (pain, redness, swelling, itching), rash, weight gain, and edema (swelling).

Precautions Do not use this medicine if you are experiencing hypoglycemia or are allergic to insulin or any of its ingredients. Alcohol consumption is unsafe as it can significantly interfere with insulin's action, increasing the risk of both low and high blood glucose levels. Caution is advised for patients with kidney, liver, or heart problems, and dosage adjustments may be necessary. Pregnant and breastfeeding women should consult their doctor as dosage requirements may change. Never stop taking Human Mixtard 50 without consulting your doctor.

Storage Human Mixtard 50 should be stored in a refrigerator at 2°C to 8°C. Do not freeze. Keep it in its original container, tightly closed. Dispose of any unused portion appropriately.

What is HUMAN MIXTARD 50 INJECTION 40 IU/ML used for?

HUMAN MIXTARD 50 INJECTION 40 IU/ML is used in the treatment of diabetes mellitus, including both Type 1 and Type 2 diabetes. It helps to improve and maintain blood sugar control in both adults and children.

How does HUMAN MIXTARD 50 INJECTION 40 IU/ML work?

This medicine is a combination of two types of insulin: human insulin (short-acting) and insulin isophane (intermediate-acting). It works by helping the body's cells, particularly in muscles and fat, to absorb glucose from the blood. Additionally, it suppresses the production of glucose by the liver, thereby ensuring rapid and consistent control of blood sugar levels throughout the day.

What is the usual dosage and how should it be administered?

The dosage of HUMAN MIXTARD 50 INJECTION 40 IU/ML is individualized based on the patient's needs, typically ranging from 0.3 to 1.0 International Unit per kilogram of body weight per day. It is administered as a subcutaneous injection (under the skin) in areas such as the abdomen, upper thigh, upper arm, or buttocks. To minimize the risk of complications like hard lumps, it is crucial to rotate the injection site with each dose. This medicine should generally be taken 15 to 30 minutes before a meal.

What are the possible side effects of HUMAN MIXTARD 50 INJECTION 40 IU/ML?

The most common side effect is hypoglycemia (low blood sugar), which can cause symptoms like lightheadedness, dizziness, anxiety, nervousness, tiredness, intense hunger, visual disturbances, shaking, sweating, and pale skin. Other possible side effects include reactions at the injection site such as pain, redness, swelling, itching, and skin thickening. Some individuals may also experience weight gain or a rash.

Is HUMAN MIXTARD 50 INJECTION 40 IU/ML safe during pregnancy or breastfeeding?

HUMAN MIXTARD 50 INJECTION 40 IU/ML is generally considered safe for use during pregnancy if prescribed by a doctor. However, close monitoring of blood sugar levels is recommended as insulin dose requirements may change during each trimester. It is also likely safe to use during breastfeeding, as studies suggest that the active substance does not pass into breastmilk in significant amounts that would be harmful to the baby.

Can HUMAN MIXTARD 50 INJECTION 40 IU/ML be taken with other medications?

Yes, this medicine can be taken with other medications, and it is often prescribed alongside other anti-diabetic drugs. However, certain medications can affect blood sugar levels when taken with insulin. Some medicines, like other diabetes medications, fluoxetine, salicylates, ramipril, and lisinopril, may increase the risk of low blood sugar. Conversely, oral contraceptives, thiazides, steroids, and thyroxine may lead to higher blood sugar. It is important to inform your doctor about all current medications, including pain killers, antibiotics, bronchodilators, and anti-depressants, to assess for potential interactions.

What precautions should be taken while using HUMAN MIXTARD 50 INJECTION 40 IU/ML?

Do not use this medicine if you are allergic to insulin or any of its ingredients, or if you are currently experiencing low blood sugar (hypoglycemia). Regular monitoring of your blood sugar levels is essential. Always carry a source of fast-acting sugar (like candy or fruit juice) to treat episodes of low blood sugar. Inform your doctor if you have any history of kidney, liver, or heart problems. It is crucial not to stop taking this injection without consulting your doctor, as this can lead to high blood sugar levels and worsen your condition. Avoid excessive alcohol consumption as it can interfere with insulin's action and cause fluctuations in blood glucose. Be cautious when driving or operating machinery, as both high and low blood sugar levels can impair your ability.

What happens if a dose of HUMAN MIXTARD 50 INJECTION 40 IU/ML is missed?

Missing a dose can lead to elevated blood sugar levels (hyperglycemia), which may cause symptoms like increased thirst, frequent urination, and drowsiness. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Never take a double dose to compensate for a missed one, as this can cause a dangerous drop in blood glucose. It is important to monitor your blood sugar levels closely if a dose is missed.

How should HUMAN MIXTARD 50 INJECTION 40 IU/ML be stored?

HUMAN MIXTARD 50 INJECTION 40 IU/ML should be stored in a refrigerator between 2°C and 8°C. It is important not to freeze the medicine, as freezing can compromise its effectiveness. Keep the medicine in its original container, tightly closed, and follow the storage instructions provided on the label to ensure its potency.