Rzole Dsr Capsule (10 Cap)

RZOLE DSR CAPSULE (10 CAP) by ABBOTT HEALTHCARE PVT. LTD.

Name

• Brand Name: Rzole DSR Capsule

Composition Rzole DSR Capsule contains a combination of two active ingredients:

• Domperidone: 30 mg
• Rabeprazole: 20 mg

Uses This medicine is primarily used to manage various gastrointestinal conditions:

• Gastroesophageal Reflux Disease (GERD) / Acid Reflux: It helps alleviate symptoms such as heartburn, chest discomfort, acidity, stomach pain, and irritation, especially when not responding to Omeprazole alone.
• Peptic Ulcer Disease: Effective in treating stomach ulcers and duodenal ulcers.
• Zollinger-Ellison Syndrome: A condition involving the overproduction of acid due to a pancreatic tumor.
• Erosive Esophagitis: Helps in healing inflammation of the food pipe lining.
• Nausea and Vomiting: Domperidone helps in relieving nausea and vomiting by increasing upper gastrointestinal tract motility.

Dosage and Administration

• Rzole DSR Capsule should be taken as prescribed by your doctor.
• It is typically taken before meals, preferably in the morning, for optimal results.
• Swallow the capsule whole with a glass of water; do not crush, chew, or break it.
• Do not stop taking the medicine suddenly, even if symptoms improve.

Side Effects Common side effects may include:

• Headache
• Diarrhea
• Dry mouth
• Stomach pain / Abdominal pain
• Flatulence (gas)
• Fatigue / Weakness
• Nausea
• Dizziness

Precautions

• Inform your doctor about any existing liver, kidney, or heart conditions.
• Use with caution in pregnant or breastfeeding women, and only under medical supervision.
• Avoid alcohol consumption as it may increase acidity and worsen symptoms, and can also increase the risk of side effects like dizziness and drowsiness.
• Do not drive or operate heavy machinery if you experience dizziness, sleepiness, or blurred vision.
• Prolonged use may lead to deficiencies in Vitamin B12, magnesium, and calcium, and increased risk of fractures.
• Inform your doctor about all other medications you are taking to avoid potential drug interactions.

Storage

• Store Rzole DSR capsules below 25°C or 30°C, protected from moisture and direct sunlight.
• Keep the medicine out of the reach of children and pets.

Here are frequently asked questions about RZOLE DSR CAPSULE:

What is RZOLE DSR CAPSULE used for?

RZOLE DSR CAPSULE is a combination medicine primarily used to treat gastroesophageal reflux disease (GERD), commonly known as acid reflux, and peptic ulcer disease. It helps relieve symptoms such as heartburn, stomach pain, irritation, indigestion, nausea, and vomiting. It is also used in conditions like Zollinger-Ellison syndrome, where the stomach produces excessive acid.

How does RZOLE DSR CAPSULE work?

RZOLE DSR CAPSULE contains two active ingredients: Rabeprazole and Domperidone. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking a specific enzyme (H+/K+ ATPase or gastric proton pump) in the stomach wall, thereby reducing the amount of acid produced. Domperidone is a prokinetic agent that increases the movement of the stomach and intestines, helping food move more efficiently through the digestive tract. It also blocks dopamine receptors in the brain's "chemoreceptor trigger zone," which helps to prevent nausea and vomiting. Together, they reduce acidity and improve gastric motility.

What is the usual dosage for RZOLE DSR CAPSULE?

RZOLE DSR CAPSULE should be taken exactly as prescribed by your doctor. It is typically taken once daily, usually one hour before a meal, preferably in the morning, with a glass of water. The capsule should be swallowed whole and not crushed, chewed, or broken, as this may reduce its effectiveness.

What are the possible side effects of RZOLE DSR CAPSULE?

Common side effects may include diarrhea, dry mouth, headache, constipation, abdominal pain, dizziness, flatulence, nausea, vomiting, and weakness. If these side effects persist or worsen, or if you experience any severe symptoms like rash, swelling, difficulty breathing, or irregular heartbeat, consult your doctor immediately. Long-term use can potentially lead to low magnesium levels, vitamin B12 deficiency, and an increased risk of bone fractures.

Is RZOLE DSR CAPSULE safe during pregnancy or breastfeeding?

RZOLE DSR CAPSULE is generally not recommended during pregnancy as its components might harm an unborn baby. If you are pregnant, think you may be pregnant, or are planning to have a baby, consult your doctor. For breastfeeding women, RZOLE DSR CAPSULE passes into breast milk in small amounts and might affect the baby. Your doctor will assess the benefits and risks before prescribing it.

Can RZOLE DSR CAPSULE be taken with other medications?

RZOLE DSR CAPSULE can interact with several medications. It's important to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions. Some known interactions include:

• Blood thinners like Clopidogrel and Warfarin, which may have increased effects.
• Anti-HIV drugs like Atazanavir and Nelfinavir, whose effectiveness may be reduced.
• Antifungals like Ketoconazole, Itraconazole, and Posaconazole.
• Heart medications like Digoxin and Amiodarone.
• Methotrexate and Tacrolimus, whose levels can increase, causing side effects.
• Antacids, which should be avoided within two hours of taking RZOLE DSR.

What precautions should be taken while taking RZOLE DSR CAPSULE?

Inform your doctor about any pre-existing medical conditions, especially liver or kidney problems, serious heart conditions (like congestive heart failure or heart rhythm problems), low magnesium levels, osteoporosis, stomach or intestinal bleeds/obstruction, or a history of gastric cancer. It's advisable to avoid alcohol, nicotine, caffeine, spicy, oily, and acidic foods, as these can stimulate stomach acid or worsen symptoms. This medicine may cause dizziness and sleepiness, so exercise caution when driving or operating machinery.

What happens if a dose of RZOLE DSR CAPSULE is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should RZOLE DSR CAPSULE be stored?

RZOLE DSR CAPSULE should be stored below 25°C or 30°C, protected from moisture and light. Keep the medicine out of the reach of children and pets.