Carbophage Xr 1000 Mg Tablet (10 Tab)

Frequently Asked Questions (FAQs) about CARBOPHAGE XR 1000 MG TABLET

CARBOPHAGE XR 1000 MG TABLET, containing Metformin Hydrochloride 1000 mg in an extended-release formulation, is a medication primarily used for managing type 2 diabetes.

1. What is CARBOPHAGE XR 1000 MG TABLET used for?

CARBOPHAGE XR 1000 MG TABLET is primarily used to manage high blood sugar levels in adults with type 2 diabetes mellitus when diet and exercise alone are not sufficient. It can also be prescribed to help manage insulin resistance and polycystic ovary syndrome (PCOS) in women.

2. How does CARBOPHAGE XR 1000 MG TABLET work?

This medicine belongs to a class called biguanides. Its active ingredient, Metformin, works in three main ways: it decreases the amount of glucose (sugar) produced by the liver, reduces the absorption of sugar from the intestines, and enhances the body's sensitivity to insulin, allowing the body to use glucose more effectively.

3. What is the usual dosage of CARBOPHAGE XR 1000 MG TABLET?

The dosage of CARBOPHAGE XR 1000 MG TABLET is individualized by your doctor. A common starting dose for extended-release metformin is 500 mg once daily with the evening meal, which may be gradually increased by your doctor. The maximum recommended dose for Metformin XR is typically 2000 mg once daily, but in some cases, a doctor may prescribe up to 2500 mg once daily. It is crucial to swallow the tablet whole with a glass of water and avoid crushing or chewing it, as this can affect its extended-release properties. It should be taken with or after a meal to minimize digestive side effects.

4. What are the possible side effects of CARBOPHAGE XR 1000 MG TABLET?

Common side effects include nausea, vomiting, diarrhea, abdominal pain or discomfort, loss of appetite, and a metallic taste in the mouth. These often subside as your body adjusts to the medication.

More serious, but rare, side effects include lactic acidosis (a buildup of lactic acid in the blood) and vitamin B12 deficiency with long-term use. Symptoms of lactic acidosis include unusual muscle pain, severe tiredness, difficulty breathing, stomach pain with nausea/vomiting, feeling cold, and a slow or irregular heartbeat. Symptoms of vitamin B12 deficiency may include fatigue, pale skin, shortness of breath, or nerve problems. If you experience any severe or persistent side effects, contact your doctor immediately.

5. Is CARBOPHAGE XR 1000 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: While some manufacturers advise against its use during pregnancy, other sources suggest that metformin is generally considered safe with a low risk of birth defects and may be continued if prescribed for type 2 diabetes or PCOS before or during pregnancy. Poorly controlled diabetes during pregnancy poses significant risks to both mother and baby, so it is crucial to consult your doctor to determine the best course of treatment.

Breastfeeding: Metformin passes into breast milk in very small quantities and is generally considered compatible with breastfeeding, with no reported adverse effects on breastfed infants. Always discuss with your doctor before using any medication while breastfeeding.

6. Can CARBOPHAGE XR 1000 MG TABLET be taken with other medications?

CARBOPHAGE XR 1000 MG TABLET can interact with certain medications. It's important to inform your doctor about all prescription, over-the-counter medicines, vitamins, and herbal supplements you are taking. Particular caution is advised with:

• Cationic medications (e.g., ranolazine, vandetanib).
• H2 receptor antagonists (e.g., cimetidine).
• Diuretics (e.g., furosemide, hydrochlorothiazide).
• Corticosteroids.
• Bronchodilators (e.g., salbutamol, terbutaline).
• Non-steroidal inflammatory agents (NSAIDs) (e.g., ibuprofen, celecoxib).
• Certain antihypertensives.
• Iodine-containing contrast media used for X-rays or scans (you may need to temporarily stop this medication).

7. What precautions should be taken while on CARBOPHAGE XR 1000 MG TABLET?

• Medical Conditions: Inform your doctor if you have kidney, liver, or heart problems, severe infections, or a history of dehydration, as these can increase the risk of serious side effects like lactic acidosis.
• Alcohol Consumption: Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis and may also affect blood sugar levels.
• Surgery/Scans: You may need to temporarily stop taking this medication before certain surgeries or X-ray/scanning procedures that involve iodine-containing contrast media.
• Vitamin B12: Long-term use may lead to vitamin B12 deficiency; your doctor may monitor your levels and recommend supplements if needed.
• Driving: If you experience dizziness or tiredness, avoid driving or operating heavy machinery until you know how the medicine affects you.

8. What happens if a dose of CARBOPHAGE XR 1000 MG TABLET is missed?

If you miss a dose, take it as soon as you remember with food. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

9. How should CARBOPHAGE XR 1000 MG TABLET be stored?

Store CARBOPHAGE XR 1000 MG TABLET in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it out of sight and reach of children and pets. The storage temperature should generally be below 30°C.