Valtoval 500 Mg Tablet (3 Tab)

VALTOVAL 500 MG Tablet

VALTOVAL 500 MG Tablet is an antiviral medication manufactured by Sun Pharmaceutical Industries Ltd., primarily used to treat various viral infections caused by the herpes virus.

• Name:

  • Common Name: Valacyclovir 500 mg Tablet
  • Brand Name: Valtoval 500 MG Tablet

• Composition:

  • Active Ingredient: Valacyclovir (500 mg)
  • Valacyclovir is a prodrug that converts to acyclovir in the body, which then works by inhibiting the viral DNA polymerase enzyme, preventing the multiplication of viruses in human cells.

• Uses: VALTOVAL 500 MG Tablet is prescribed for the treatment and management of infections caused by herpes viruses, including:

  • Herpes labialis (cold sores)
  • Genital herpes infection
  • Herpes zoster (shingles)
  • It also helps prevent cytomegalovirus (CMV) infection after organ transplantation.

• Dosage and Administration:

  • Take the tablet whole with a glass of water, with or without food, as advised by your doctor.
  • Do not chew, crush, or break the tablet.
  • It is crucial to complete the full course of treatment as prescribed, even if symptoms improve, to ensure complete infection clearance and prevent relapse.
  • Drink plenty of water to prevent dehydration and kidney-related side effects.

• Side Effects:

  • Common: Headache, nausea, abdominal pain, dizziness, vomiting, diarrhea, and increased liver enzymes.
  • Serious (rare): Thrombotic Thrombocytopenic Purpura/Hemolytic Uremic Syndrome (TTP/HUS) in advanced HIV patients, severe allergic reactions (rash with fever, enlarged lymph nodes, elevated liver enzymes).

• Precautions:

  • Inform your doctor about any kidney problems, as dose adjustments may be necessary.
  • Use with caution in elderly patients, those with a history of bone marrow or kidney transplant, or advanced HIV infection.
  • Consult a doctor if pregnant or breastfeeding.
  • Avoid driving or operating heavy machinery if you experience dizziness.
  • Do not discontinue the medication suddenly.
  • If treating genital herpes, avoid sexual intercourse or use protective measures to prevent transmission.

• Storage:

  • Store below 30°C.
  • Keep in a cool and dry place, away from direct sunlight, moisture, and heat.
  • Keep out of sight and reach of children.

Here are frequently asked questions about Valtoval 500 mg Tablet, which contains the active ingredient Valacyclovir:

What is Valtoval 500 mg Tablet used for?

Valtoval 500 mg Tablet is an antiviral medication primarily used to treat various infections caused by herpes viruses. This includes herpes labialis (cold sores), genital herpes infection (both initial and recurrent episodes), herpes zoster (shingles), and chickenpox. It also helps prevent cytomegalovirus following organ transplantation.

How does Valtoval 500 mg Tablet work?

Valtoval 500 mg Tablet contains Valacyclovir, which is a prodrug. In the body, Valacyclovir is rapidly converted into its active form, acyclovir, and L-valine. Acyclovir works by inhibiting viral DNA synthesis and replication, specifically targeting the viral DNA polymerase, which stops the virus from multiplying and spreading. This helps the body to heal more effectively and clears up the infection.

What is the usual dosage for Valtoval 500 mg Tablet?

The dosage of Valtoval (Valacyclovir) varies depending on the condition being treated and should be taken as prescribed by your doctor.

• Cold Sores (Herpes Labialis): For adults, the recommended dosage is typically 2 grams (four 500 mg tablets) taken twice daily for 1 day, with doses taken 12 hours apart.
• Genital Herpes (Initial Episode): Adults usually take 1 gram (two 500 mg tablets) twice daily for 10 days.
• Genital Herpes (Recurrent Episodes): Adults typically take 500 mg (one 500 mg tablet) twice daily for 3 days.
• Herpes Zoster (Shingles): For adults, the recommended dosage is 1 gram (two 500 mg tablets) three times a day for 7 days.
• Suppressive Therapy for Recurrent Genital Herpes: For immunocompetent adults, 1 gram once daily, or 500 mg once daily for those with 9 or fewer recurrences per year. Therapy is most effective when started at the earliest sign or symptom of an outbreak.

What are the possible side effects of Valtoval 500 mg Tablet?

Common side effects of Valtoval (Valacyclovir) include headache, nausea, abdominal pain, dizziness, and vomiting. Other common side effects can include diarrhea, joint pain, tiredness, and flu-like symptoms. Serious side effects, though rare, can include kidney problems, agitation, confusion, hallucinations, and blood disorders. If you experience serious side effects like swelling of the face, lips, tongue, or throat, or changes in urination, contact your doctor immediately.

Is Valtoval 500 mg Tablet safe during pregnancy or breastfeeding?

Pregnancy: Valacyclovir should only be used during pregnancy if clearly needed, and after consulting with a doctor. Studies show that Valacyclovir (valaciclovir) use in pregnancy appears to be safe. Breastfeeding: Valacyclovir passes into breast milk. While milk levels are reported to be very low and it is unlikely to affect the nursing infant, it is best to discuss with your doctor or pharmacist before taking Valacyclovir while breastfeeding, especially if the baby was born prematurely.

Can Valtoval 500 mg Tablet be taken with other medications?

Valtoval (Valacyclovir) can interact with other medications, particularly those that affect kidney function. It's crucial to inform your doctor about all medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Significant interactions have been noted with drugs that can increase the risk of kidney damage, such as certain antibiotics (e.g., aminoglycosides like gentamicin, tobramycin), immunosuppressants (e.g., cyclosporine, tacrolimus), and NSAIDs (e.g., ibuprofen, naproxen). Cimetidine and probenecid can also increase levels of valacyclovir in the body.

What precautions should be taken while using Valtoval 500 mg Tablet?

It is important to stay well hydrated by drinking plenty of water while taking Valtoval (Valacyclovir) to help prevent kidney issues. Inform your doctor if you have kidney disease, a weakened immune system (such as due to HIV/AIDS), or have had a bone marrow or kidney transplant, as dosage adjustments or special monitoring may be necessary. If you experience dizziness, avoid driving or operating machinery. Also, Valtoval does not prevent the spread of herpes, so continue to practice safe sex, especially during outbreaks.

What happens if a dose of Valtoval 500 mg Tablet is missed?

If you miss a dose of Valtoval (Valacyclovir), take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double doses to make up for a forgotten one.

How should Valtoval 500 mg Tablet be stored?

Valtoval (Valacyclovir) tablets should be stored at room temperature, typically between 15°C and 25°C (59°F and 77°F). Keep the medication in its original container, tightly closed, and away from excess heat, moisture, and direct light. Keep all medications out of the reach of children.