Oleanz Plus Tablet (10 Tab)

OLEANZ PLUS TABLET (10 TAB) by SUN PHARMA LABORATORIES LTD.

OLEANZ PLUS TABLET is a prescription medication combining an antidepressant and an antipsychotic, primarily used for managing specific mental health conditions.

• Name

  • Brand Name: Oleanz Plus Tablet
  • Common Name: (Refers to the combination of its active ingredients)

• Composition

  • Each tablet contains Fluoxetine 20 mg and Olanzapine 5 mg.

• Uses OLEANZ PLUS TABLET is prescribed for the treatment of:

  • Schizophrenia
  • Bipolar disorder (manic depression), particularly for depression associated with bipolar disorder
  • Treatment-resistant depression (when other antidepressants have not been effective) This combination works by helping to restore the balance of certain natural substances (neurotransmitters like dopamine, serotonin, and norepinephrine) in the brain, improving mood, sleep, appetite, and energy levels.

• Dosage and Administration

  • Typically, OLEANZ PLUS TABLET is taken once daily, with or without food, as advised by your doctor.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • It is recommended to take the medicine at the same time each day to maintain consistent levels in the body.
  • Do not stop taking this medicine abruptly without consulting your doctor, as it may worsen symptoms or cause withdrawal effects.

• Side Effects

  • Common Side Effects: Drowsiness, dizziness, lightheadedness, restlessness, irritability, tremors, dry mouth, constipation, increased appetite, weight gain, fatigue, nausea, headache, insomnia, and blurred vision.
  • Serious Side Effects (Seek immediate medical attention if experienced): Suicidal thoughts (especially in younger people), severe allergic reactions (rash, swelling), high blood sugar or diabetes, unusual body movements (tardive dyskinesia), serotonin syndrome (confusion, sweating, fast heart rate), seizures, and fast/irregular heartbeat.

• Precautions

  • Avoid alcohol consumption during treatment as it may increase the risk of side effects like drowsiness and dizziness.
  • Pregnant or breastfeeding women should consult their doctor before use, as it may be unsafe during pregnancy and breastfeeding.
  • This medicine may cause drowsiness or dizziness, so avoid driving or operating heavy machinery until you know how it affects you.
  • Use with caution in elderly patients and those with a history of glaucoma, diabetes, liver or kidney disease, heart conditions, stroke, Parkinson's disease, epilepsy, prostate problems, or blood disorders.
  • Not recommended for children and adolescents under 18 years of age for depression.
  • Inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions, especially with MAOIs.

• Storage

  • Store OLEANZ PLUS TABLET at room temperature (20-25°C), away from direct heat, light, and moisture.
  • Keep it out of the sight and reach of children and pets.

OLEANZ PLUS TABLET (10 TAB) is a combination medication containing Olanzapine and Fluoxetine, used to treat certain mental health conditions. Here are some frequently asked questions about this medicine:

What is Oleanz Plus Tablet used for?

Oleanz Plus Tablet is primarily used to treat depression associated with bipolar I disorder (bipolar depression) and treatment-resistant depression (when other antidepressants have not been effective). It can help improve mood, sleep, appetite, and energy levels. It is also used in the treatment of schizophrenia.

How does Oleanz Plus Tablet work?

Oleanz Plus Tablet is a combination of two medicines: Fluoxetine and Olanzapine. Olanzapine is an atypical antipsychotic that works by balancing brain chemicals like dopamine and serotonin. Fluoxetine is a selective serotonin reuptake inhibitor (SSRIs) antidepressant that increases the amount of serotonin in the brain. The combined action helps to restore the balance of these natural substances in the brain, leading to an improvement in mood and a reduction in symptoms of depression, anxiety, hallucinations, and disorganized thinking.

What is the usual dosage of Oleanz Plus Tablet?

Oleanz Plus Tablet is typically taken once daily, usually in the evening, with or without food, as advised by your doctor. The dosage and duration of treatment will be determined by your doctor based on your medical condition and response to treatment. For bipolar I depression, a common starting dose for adults is one capsule containing 6 mg of olanzapine and 25 mg of fluoxetine. For children aged 10 to 17 years, a starting dose might be 3 mg of olanzapine and 25 mg of fluoxetine. It is crucial to take this medicine regularly at the same time each day to maintain a consistent level in your body.

What are the possible side effects of Oleanz Plus Tablet?

Common side effects of Oleanz Plus Tablet include drowsiness, tiredness, increased appetite, weight gain, dry mouth, difficulty in paying attention, sleepiness, blurred vision, and dizziness. Other possible side effects can include nausea, constipation, restlessness, tremors, headache, and increased blood sugar or cholesterol levels. Serious side effects, though rare, can include suicidal thoughts (especially in younger people), severe allergic reactions, high blood sugar or diabetes, unusual body movements (tardive dyskinesia), and serotonin syndrome. Contact your healthcare provider immediately if you experience severe side effects.

Is Oleanz Plus Tablet safe during pregnancy or breastfeeding?

Oleanz Plus Tablet is generally not recommended during pregnancy unless clearly needed, as animal studies have shown harmful effects on the developing baby, and limited human data suggests potential risks. It is considered unsafe to use during breastfeeding, as the drug may pass into breast milk and harm the baby. Always consult your doctor to weigh the benefits and potential risks before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Can it be taken with other medications?

Oleanz Plus Tablet can interact with several medications, potentially leading to serious adverse effects. It should not be taken with monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing them. Concomitant use with other serotonergic drugs (e.g., other SSRIs, SNRIs, tricyclic antidepressants, triptans, tramadol) can increase the risk of serotonin syndrome. It may also interact with pimozide, thioridazine, medicines for high blood pressure, NSAIDs, aspirin, warfarin, carbamazepine, and certain CYP2D6 inhibitors. Always inform your doctor about all other medications, including over-the-counter drugs, herbal supplements, and vitamins, to avoid potential drug interactions.

What precautions should be taken?

Several precautions should be taken while using Oleanz Plus Tablet. Avoid consuming alcohol as it can worsen side effects like drowsiness and dizziness. Do not drive or operate heavy machinery until you know how this medicine affects you, as it can cause drowsiness, dizziness, or blurred vision. Inform your doctor if you have a history of diabetes, heart disease, liver or kidney problems, epilepsy, glaucoma, Parkinson's disease, or a family history of suicide or blood clots. This medication can cause weight gain and changes in blood sugar and cholesterol levels, so regular monitoring is recommended. There's a boxed warning about increased risk of suicidal thoughts and behaviors in patients aged 24 and under.

What happens if a dose is missed?

If you miss a dose of Oleanz Plus Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How should it be stored?

Oleanz Plus Tablet should be stored at room temperature, generally below 30°C (86°F), away from direct heat, sunlight, and moisture. Keep it out of reach of children and pets. Do not store it in a refrigerator, and do not use the medication after the expiration date.