Evacuol

EVACUOL Granules

EVACUOL Granules, manufactured by FRANCO-INDIAN PHARMACEUTICALS PVT LTD, is a natural evacuant designed to provide gentle and effective relief from constipation and related digestive issues.

Composition

EVACUOL contains a fixed-dose combination of:

• Sennosides A & B: 18.00 %w/w. These are natural laxatives that stimulate bowel movements.
• Karaya Gum (Mucilage): 31.00 %w/w. This natural substance acts as a bulk-forming laxative, absorbing water to increase stool volume and soften feces, thereby aiding passage through the digestive system.

Uses

EVACUOL is prescribed for the symptomatic relief and management of various forms of constipation and digestive discomfort, including:

• Occasional constipation.
• Promoting regularity of bowel movements.
• Constipation associated with diabetes, old age, or the post-operative period.
• Constipation in cardiovascular patients where straining must be avoided.
• Relief of hemorrhoidal pain by promoting softer stools.
• Managing digestive issues like flatulence, abdominal distension, and bloating.

Dosage and Administration

For adults, the typical dosage is one to two level measures of granules after each meal or before retiring to bed. The granules should be swallowed with a full glass of water and should not be crushed or chewed. Children should take half the adult dosage or as directed by a physician. It is important to follow the recommended dosage and instructions for use as directed by a doctor.

Side Effects

Common side effects may include:

• Vomiting
• Diarrhea
• Nausea
• Dehydration
• Abdominal cramping or pain Isolated cases of severe diarrhea, hyponatremia, and anaphylactoid reactions have been reported post-marketing.

Precautions

• Pregnancy and Breastfeeding: Use during pregnancy is not recommended unless prescribed by a doctor. It should be used with caution while breastfeeding, and medical consultation is advised.
• Children: Not recommended for use in children without proper medical supervision.
• Medical Conditions: EVACUOL is contraindicated in patients with intestinal obstruction, appendicitis, inflammatory bowel disease, paralytic ileus, severe dehydration, or abdominal pain of unknown origin.
• Duration of Use: This medicine is intended for short-term use to relieve occasional constipation. Prolonged use without medical supervision is not recommended and can lead to fluid and electrolyte imbalance and hypokalemia.
• Interactions: There are no known significant drug-drug or drug-food interactions specifically mentioned for EVACUOL granules. However, a different formulation of Evacuol (oral drops with sodium picosulfate) may have interactions with antibiotics and other medications.
• General Advice: Maintain a healthy lifestyle, including a balanced diet rich in fiber, adequate water intake, and regular exercise while using this medicine. Consult a doctor if symptoms worsen or persist after 6 days, or if no defecation occurs after 72 hours.

Storage

Store EVACUOL Granules at room temperature (20-25°C). Protect from moisture and direct sunlight. Keep out of the reach of children.

What is Evacuol used for?

Evacuol Granules, manufactured by Franco-Indian Pharmaceuticals Pvt Ltd, is a natural evacuant and laxative used for the symptomatic relief of occasional constipation. It addresses various types of constipation, including those associated with diabetes, old age, post-operative periods, and to facilitate bowel movements in patients with hemorrhoids or cardiovascular conditions where straining must be avoided. It can also help relieve symptoms like flatulence, abdominal distension, and bloating.

How does Evacuol work?

Evacuol Granules combine the actions of Sennosides A & B and Karaya Gum. Sennosides A & B are stimulant laxatives that work by keeping water in the intestines and directly stimulating the nerve endings in the large intestine and rectum, which increases intestinal motility and promotes bowel movements. Karaya Gum acts as a bulk-forming laxative; it absorbs water and expands, increasing the volume and softening the fecal mass, which aids in its passage through the digestive system.

What is the usual dosage of Evacuol Granules?

For adults, the recommended dosage is typically one to two level measures of granules, taken after each meal or before going to bed. The granules should be swallowed with a full glass of water without chewing. For children, half the adult dosage is usually recommended, or as directed by a physician. It is important to follow the recommended dosage and not exceed it.

What are the possible side effects of Evacuol?

While generally well-tolerated, Evacuol can cause some side effects, especially with high doses or prolonged use. These may include skin rashes, abdominal pain, diarrhea, nausea, vomiting, dehydration, and abdominal cramping. Overuse can lead to excessive loss of water and electrolytes, particularly potassium, which may result in muscle weakness and heart function disorders, and could even worsen constipation. Any adverse reactions should be reported to your healthcare provider.

Are there any precautions I should take while using Evacuol?

Do not take more than the recommended doses, and Evacuol should not be used continuously or for extended periods without consulting a doctor to investigate the cause of constipation. Prolonged or high-dose treatment can lead to excessive potassium loss and electrolyte imbalances. If no bowel movement occurs after 72 hours, or if symptoms worsen or persist after 6 days, seek medical advice. Evacuol is contraindicated if you are allergic to its components, or have inflammatory intestinal disease, acute abdominal pain, symptoms of appendicitis, intestinal obstruction, or severe dehydration. It is not generally recommended for children without proper medical supervision.

Can Evacuol be taken with other medications?

Yes, but caution is advised. Due to its laxative action, Evacuol can increase gastrointestinal transit, potentially affecting the absorption of other orally administered medications such as antiepileptics, contraceptives, and antidiabetics. It is advisable to take other oral medications at least one hour before or several hours after Evacuol. Antibiotics may reduce the laxative effect of Evacuol by altering the gastrointestinal flora. Additionally, taking Evacuol with medicines that affect electrolytes (e.g., amphotericin B, corticosteroids, diuretics) could worsen potassium loss. Inform your doctor about all medications you are taking.

Is Evacuol safe during pregnancy or breastfeeding?

Pregnancy: The use of Evacuol during pregnancy is generally not recommended unless specifically prescribed by a doctor. While long experience with similar laxatives has shown no evidence of undesirable effects during pregnancy, it should only be used on medical advice. Lifestyle interventions like increased fiber, fluids, and exercise are usually recommended as a first approach for constipation during pregnancy.

Breastfeeding: Evacuol should be used with caution while breastfeeding. Some sources indicate that most laxatives are minimally absorbed into breast milk, but it's important to consult your doctor or a pediatrician before use.

What happens if a dose is missed?

If you miss a dose of Evacuol, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

How should Evacuol Granules be stored?

Evacuol Granules should be stored in a cool, dry place, protected from direct sunlight and strong-smelling substances. It should be kept out of the reach of children. The ideal storage temperature is typically around 25 degrees Celsius. Always check the product label for specific storage instructions.