Chymoflam-ap Tab

CHYMOFLAM-AP TAB by AGLOWMED LTD.

Name: Chymoflam AP Tablet (Brand Name)

Composition: Chymoflam AP Tablet is a combination medication containing three active ingredients:

• Aceclofenac: 100 mg
• Paracetamol (Acetaminophen): 325 mg
• Trypsin-Chymotrypsin: 50000 AU

Uses: Chymoflam AP Tablet is primarily used to manage pain and inflammation in various conditions. It is prescribed for:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing Spondylitis
• Lower back pain and neck discomfort
• Muscular pain
• Dental pain (including post-procedure)
• Postoperative pain
• Recovery from soft tissue injuries like sprains and strains
• Reduction of post-traumatic inflammation and swelling (oedema)

Dosage and Administration: This medicine should be taken orally with food to minimize the risk of stomach upset. The tablet should be swallowed whole with a glass of water and not crushed or chewed. The dosage and duration of treatment are determined by a healthcare professional based on the severity of the condition and the patient's response. Do not exceed the prescribed dose or duration.

Side Effects: Common side effects may include:

• Abdominal discomfort, pain, indigestion, heartburn
• Nausea, vomiting
• Diarrhea, constipation, flatulence
• Dizziness, headache
• Rash
• Loss of appetite
• Mild swelling (edema)

Serious side effects, though rare, can include:

• Severe allergic reactions (anaphylaxis, severe skin reactions like Stevens-Johnson Syndrome)
• Severe gastrointestinal events (bleeding, peptic ulcers, black/tarry stools)
• Kidney dysfunction or liver toxicity (jaundice, dark urine, severe abdominal pain)

Precautions:

• Allergy: Do not take if allergic to aceclofenac, paracetamol, trypsin, chymotrypsin, or other ingredients.
• Gastrointestinal Issues: Use with caution in patients with a history of peptic ulcers, gastrointestinal bleeding, or inflammation of the intestines.
• Liver/Kidney Impairment: Exercise caution in patients with mild to moderate liver or kidney impairment; not recommended for severe cases. Long-term use can cause kidney damage.
• Heart Conditions: Caution is advised for patients with heart problems, high blood pressure, or high cholesterol.
• Pregnancy and Breastfeeding: Consult a doctor before use if pregnant or breastfeeding.
• Alcohol: Avoid consuming alcohol as it may increase the risk of certain side effects, including liver damage and increased drowsiness.
• Drug Interactions: Inform your doctor about all other medications being taken, especially SSRIs, diuretics, ACE inhibitors, lithium, and anti-tubercular medicines, as interactions may occur.
• Driving/Operating Machinery: May cause drowsiness and dizziness, so avoid driving or operating heavy machinery until you know how the medicine affects you.
• Children and Elderly: Not recommended for children as safety and efficacy are not established. Use with caution in elderly patients.

Storage: Store Chymoflam AP Tablet at room temperature, below 30°C. Keep the medicine away from direct light and moisture to maintain its effectiveness. Ensure it is kept out of the reach of children and pets. Always check the expiry date and do not use the medicine if it has passed.

What is CHYMOFLAM-AP TAB used for?

CHYMOFLAM-AP TAB is primarily used to relieve pain and inflammation. It is effective in managing conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, general musculoskeletal pain, lower back and neck discomfort, dental pain, and post-operative pain. It also helps reduce swelling and fever.

How does CHYMOFLAM-AP TAB work?

This medicine is a combination of three active ingredients: Aceclofenac, Paracetamol (Acetaminophen), and Trypsin-Chymotrypsin. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol, an analgesic and antipyretic, work by blocking the production of certain chemical messengers in the brain and spinal cord called prostaglandins, which are responsible for pain, inflammation, and fever. Trypsin-Chymotrypsin, a combination of proteolytic enzymes, helps break down abnormal proteins at the site of inflammation, thereby reducing swelling and assisting in tissue repair.

What is the usual dosage for CHYMOFLAM-AP TAB?

The dosage of CHYMOFLAM-AP TAB should be strictly as advised by your doctor. It is generally recommended to take the tablet with food to prevent stomach upset. Do not exceed the prescribed dose or use it for a longer duration than recommended by your doctor.

What are the possible side effects of CHYMOFLAM-AP TAB?

Common side effects may include abdominal discomfort, indigestion, nausea, dizziness, rash, heartburn, stomach pain, loss of appetite, diarrhea, and flatulence. More serious, but rare, side effects can include peptic ulcers, gastrointestinal bleeding, liver damage, or kidney dysfunction. If you experience severe symptoms, consult your doctor immediately.

Is CHYMOFLAM-AP TAB safe during pregnancy or breastfeeding?

CHYMOFLAM-AP TAB is generally considered unsafe for use during pregnancy, as animal studies have shown potential harmful effects on the developing baby. For breastfeeding mothers, caution is advised, and limited information is available; therefore, it's crucial to consult your doctor before taking this medicine.

Can CHYMOFLAM-AP TAB be taken with other medications?

CHYMOFLAM-AP TAB can interact with several medications. Its effects may be enhanced by anticoagulants like warfarin or heparin, increasing the risk of bleeding. Antiplatelet medications such as clopidogrel or aspirin can also increase the risk of bleeding when taken with CHYMOFLAM-AP TAB. Selective serotonin reuptake inhibitors (SSRIs) may increase the risk of gastrointestinal bleeding. Diuretics and ACE inhibitors may have reduced blood pressure-lowering effects. Aceclofenac in this tablet can also increase serum lithium levels, potentially leading to toxicity. Long-term use of paracetamol with isoniazid (an anti-tubercular medicine) may increase the risk of liver damage. It's important to avoid taking it with other medicines containing acetaminophen. Always inform your doctor about all medications you are currently taking.

What precautions should be taken while using CHYMOFLAM-AP TAB?

Several precautions should be observed:

• Alcohol: Avoid consuming alcohol, as it may increase the risk of drowsiness, dizziness, and stomach bleeding.
• Driving & Machinery: This medicine may cause dizziness and drowsiness, so avoid driving or operating machinery until you know how it affects you.
• Medical Conditions: Use with caution if you have mild to moderate liver impairment, kidney issues, peptic ulcers, asthma, or heart problems.
• Allergies: Do not take if you are allergic to aceclofenac, paracetamol, trypsin, chymotrypsin, or any other ingredients.
• Children: CHYMOFLAM-AP TAB is not recommended for children as its safety and efficacy have not been established.

What happens if a dose of CHYMOFLAM-AP TAB is missed?

If you forget to take a scheduled dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects.

How should CHYMOFLAM-AP TAB be stored?

Store CHYMOFLAM-AP TAB at room temperature, ideally below 30°C. Keep the medicine away from direct light and moisture to maintain its effectiveness. Always ensure it is kept out of the reach of children and pets. Remember to check the expiry date and do not use the medicine if it has passed this date.