Etoshine 120 Mg Tablet (10 Tab)

ETOSHINE 120 MG TABLET

Name:

• Brand Name: Etoshine 120 MG Tablet
• Common Name: Etoricoxib

Composition: Etoshine 120 MG Tablet contains Etoricoxib 120 mg as its active ingredient. Etoricoxib is a selective cyclooxygenase-2 (COX-2) inhibitor, belonging to the class of non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the release of prostaglandins, chemical messengers responsible for pain, swelling, and inflammation in the body.

Uses: Etoshine 120 MG Tablet is prescribed for the symptomatic relief of pain, swelling, and inflammation in various conditions, primarily in adults aged 16 years and older. These conditions include:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Acute gouty arthritis
• Moderate pain after dental surgery
• Acute pain (e.g., post-surgical pain)
• Chronic low back pain
• Dysmenorrhea (painful menstruation)

Dosage and Administration: Etoshine 120 MG Tablet should be taken orally, with or without food, as directed by a healthcare professional. The tablet should be swallowed whole with a glass of water and not crushed, broken, or chewed.

• For acute gouty arthritis, the recommended dose is 120 mg once daily, typically for a maximum of 8 days.
• For post-operative dental surgery pain, the recommended dose can be 90 mg once daily, limited to a maximum of 3 days.
• The maximum daily dose should not exceed 120 mg.

Side Effects: Common side effects may include:

• Stomach pain, indigestion (dyspepsia), heartburn, nausea, vomiting, diarrhoea, constipation, flatulence
• Headache, dizziness
• Swelling of the legs (edema)
• Increased blood pressure (hypertension)
• Palpitations
• Flu-like symptoms (fever, cold, cough, or sore throat), general weakness/fatigue
• Dry socket (after dental surgery)

Serious side effects can include an increased risk of heart attack, stroke, kidney problems, gastrointestinal bleeding, ulcers or perforation, liver issues, and severe allergic reactions.

Precautions:

• Allergies: Do not use if allergic to etoricoxib or other NSAIDs like aspirin or ibuprofen.
• Cardiovascular Health: Use with caution in patients with a history of heart problems (heart failure, heart attack, stroke) or uncontrolled high blood pressure. Regular blood pressure monitoring may be advised.
• Liver and Kidney Impairment: Caution is advised in patients with kidney or liver disease. Dose adjustments may be necessary, and it is not recommended for severe liver or kidney problems.
• Gastrointestinal Issues: Avoid in patients with active stomach ulcers, gastrointestinal bleeding, or inflammatory bowel disease.
• Pregnancy and Breastfeeding: Etoshine 120 MG Tablet is not recommended during pregnancy, especially in the third trimester, and its use during breastfeeding is generally advised against as it is unknown if it passes into human milk.
• Driving and Operating Machinery: May cause dizziness or sleepiness; therefore, avoid driving or operating heavy machinery until you know how the medicine affects you.
• Alcohol: Avoid consuming alcohol as it may increase the risk of side effects.
• Drug Interactions: Concomitant use with anticoagulants (like warfarin) may increase the risk of bleeding. Interactions with other NSAIDs, antihypertensive medicines, birth control pills, and immunosuppressants (like cyclosporin) are also possible.

Storage: Store in a cool and dry place, away from direct sunlight and moisture. Keep out of sight and reach of children. It should be stored at 10ºC to 25ºC or below 30ºC.

What is Etoshine 120 MG Tablet used for?

Etoshine 120 MG Tablet is a pain-relieving medicine used to treat pain, swelling, and inflammation in various conditions. It is primarily prescribed for adults (16 years and older) with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout. It is also used for short-term relief of moderate pain after dental surgery.

How does Etoshine 120 MG Tablet work?

Etoshine 120 MG Tablet contains Etoricoxib, which is a selective COX-2 inhibitor, a type of non-steroidal anti-inflammatory drug (NSAID). It works by blocking the action of a specific enzyme in the body called COX-2. This enzyme is responsible for producing prostaglandins, chemical messengers that cause pain, swelling, and inflammation. By inhibiting COX-2, Etoricoxib reduces the production of these prostaglandins, thereby alleviating pain and inflammation.

What is the usual dosage of Etoshine 120 MG Tablet?

The dosage of Etoshine 120 MG Tablet depends on the condition being treated and individual response. It should always be taken as directed by your doctor. Generally, for acute gouty arthritis, the recommended dose is 120 mg once daily, typically for a maximum of 8 days. For postoperative dental surgery pain, the recommended dose is 90 mg once daily, limited to a maximum of 3 days. For conditions like osteoarthritis, the recommended dose can be 30 mg or 60 mg once daily, while for rheumatoid arthritis and ankylosing spondylitis, it is typically 90 mg once daily. The tablet can be taken with or without food, but it may act more quickly when taken without food. It should be swallowed whole with a glass of water and not crushed, chewed, or broken.

What are the possible side effects of Etoshine 120 MG Tablet?

Common side effects of Etoshine 120 MG Tablet may include stomach pain, indigestion, nausea, vomiting, diarrhea, headache, and dizziness. Other possible side effects include swelling of the face, lips, eyelids, tongue, hands and feet (edema), increased blood pressure, fatigue, flu-like illness, heartburn, and constipation. If these side effects persist or worsen, it is important to consult your doctor.

Is Etoshine 120 MG Tablet safe during pregnancy or breastfeeding?

Etoshine 120 MG Tablet is generally not recommended for use during pregnancy and is considered potentially unsafe. It is contraindicated in pregnant women as it may show toxic effects on the fetus. For breastfeeding women, Etoshine 120 MG Tablet is also contraindicated, or should only be used with caution if prescribed by a doctor, as it is unknown if it passes into breast milk.

Can Etoshine 120 MG Tablet be taken with other medications?

Etoshine 120 MG Tablet can interact with various medications.

• Other NSAIDs or Salicylates: Taking it with other NSAIDs like ibuprofen, aspirin (high doses), or diclofenac can increase the risk of gastrointestinal toxicity and stomach ulcers.
• Anticoagulants: If taken with blood thinners like warfarin, it may increase the risk of bleeding, and regular monitoring of INR (prothrombin time) is recommended.
• Antihypertensive Medicines: It can reduce the effectiveness of blood pressure-lowering medications such as ACE inhibitors (e.g., enalapril), ARBs (e.g., losartan), beta-blockers, and diuretics (water pills). Blood pressure monitoring is necessary.
• Other Medications: Caution is also advised with certain medicines like digoxin (for heart disease), lithium (for depression), salbutamol (for asthma), rifampicin (antibiotic), and immunosuppressants like cyclosporine. Always inform your doctor about all medicines, supplements, or herbal products you are currently taking.

What precautions should be taken?

Several precautions should be taken when using Etoshine 120 MG Tablet:

• Allergies: Do not take if you are allergic to etoricoxib, other NSAIDs like aspirin, or any similar medicines.
• Cardiovascular Health: Use with caution if you have a history of heart problems (e.g., heart failure, heart attack, stroke), high blood pressure (especially uncontrolled), diabetes, or high cholesterol, as it may increase the risk of cardiovascular events. Regular blood pressure monitoring is recommended.
• Liver and Kidney Issues: Avoid if you have severe liver or kidney problems. Use with caution in mild to moderate liver impairment or existing kidney disease, and dose adjustments may be necessary.
• Gastrointestinal Issues: Avoid if you have stomach ulcers, gastrointestinal bleeding, or inflammatory bowel disease.
• Driving and Machinery: Etoshine 120 MG Tablet may cause dizziness, drowsiness, or affect vision, so avoid driving or operating heavy machinery until you know how the medicine affects you.
• Alcohol: Avoid alcohol consumption as it may worsen stomach irritation and increase the risk of gastrointestinal bleeding.
• Children: Not recommended for use in children below 16 years of age.
• Dehydration: Use with caution if you are dehydrated due to vomiting or diarrhea.

What happens if a dose is missed?

If you forget to take a dose of Etoshine 120 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should it be stored?

Etoshine 120 MG Tablet should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of sight and reach of children. The medicine should be stored at temperatures between 10ºC to 25ºC or below 30ºC.