Nebistar T Tablet (10 Tab)

NEBISTAR T TABLET

NEBISTAR T TABLET is a medication manufactured by Lupin Ltd., primarily prescribed for the management of hypertension, commonly known as high blood pressure. This combination medicine is particularly beneficial for individuals whose blood pressure is not adequately controlled with a single medication.

Composition Each NEBISTAR T TABLET contains:

• Nebivolol: 5 mg
• Telmisartan: 40 mg

Nebivolol is a beta-blocker that works by relaxing blood vessels and slowing the heart rate, thereby improving blood circulation and decreasing blood pressure. Telmisartan is an angiotensin receptor blocker (ARB) that functions by blocking the hormone angiotensin, leading to the relaxation and widening of blood vessels.

Uses NEBISTAR T TABLET is used for:

• Managing hypertension (high blood pressure).
• Reducing the risk of serious heart-related complications such as heart attack and stroke.
• Treatment of mild to moderate heart failure and angina (chest pain).

Dosage and Administration NEBISTAR T TABLET should be taken exactly as directed by your doctor.

• Typically, it is taken once daily, preferably at the same time each day.
• The tablet can be taken with or without food.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• Do not exceed the prescribed dosage without consulting your doctor, as dosage can vary based on the severity of your condition and response to the medicine.

Side Effects Common side effects may include:

• Headache
• Dizziness
• Fatigue/Weakness
• Nausea
• Diarrhea
• Slow heart rate (bradycardia)
• Low blood pressure (hypotension)
• Cold extremities or numbness of extremities
• Increased potassium levels in blood
• Swelling in legs, ankles, or feet (peripheral oedema)

Less common but potentially serious side effects can include allergic reactions (rash, itching, swelling), shortness of breath, chest pain, worsening of heart failure, and changes in blood sugar levels. In case of an overdose, symptoms like severe low blood pressure, very slow heart rate, fainting, or kidney failure may occur, requiring immediate medical attention.

Precautions

• Pregnancy and Breastfeeding: NEBISTAR T TABLET is contraindicated during pregnancy due to definite evidence of risk to the developing baby. Consult your doctor if you are breastfeeding before taking this medication.
• Alcohol Consumption: It is advisable to limit or avoid alcohol consumption while taking this medicine, as it may lead to severe low blood pressure.
• Medical Conditions: Inform your doctor if you have liver impairment, kidney problems, heart conditions (e.g., severe heart failure, very slow heart rate), diabetes (especially if treated with aliskiren), bile duct obstruction, or poor blood circulation. Caution is also advised for conditions like low blood pressure, metabolic acidosis, untreated phaeochromocytoma, Raynaud's disease, or thyroid overactivity.
• Driving and Machinery: This medicine may cause dizziness or fatigue, so exercise caution when driving or operating machinery.
• Drug Interactions: Inform your doctor about all other medications, supplements, and herbal remedies you are taking, as interactions can occur with CYP2D6 inhibitors (e.g., quinidine, fluoxetine), NSAIDs (e.g., indomethacin), and antidiabetic agents (e.g., metformin).
• Food Interactions: While there are no known specific interactions with food, a balanced diet is generally advised. Avoid potassium-rich foods and supplements.

Storage Store NEBISTAR T TABLET in a cool, dry place, away from direct sunlight, and ideally below 30°C. Keep this medicine out of the reach and sight of children. Always check the expiry date before use.

What is NEBISTAR T TABLET used for?

NEBISTAR T TABLET is primarily used to manage high blood pressure, a condition known as hypertension. It is typically prescribed when blood pressure is not adequately controlled by a single medication. This medicine also helps to reduce the risk of serious heart-related complications such as heart attack and stroke.

How does NEBISTAR T TABLET work?

NEBISTAR T TABLET is a combination of two active ingredients: Nebivolol (5 mg) and Telmisartan (40 mg). Nebivolol works by selectively blocking certain receptors in your heart, which decreases your heart rate and the force of each heartbeat. It also helps widen your blood vessels. Telmisartan works by blocking the action of a hormone called angiotensin II, which normally causes blood vessels to constrict. By blocking this action, Telmisartan relaxes and widens blood vessels, reducing blood volume and ultimately lowering blood pressure. This dual action provides a comprehensive approach to managing hypertension.

What is the usual dosage for NEBISTAR T TABLET?

The dosage of NEBISTAR T TABLET should always be taken as directed by your doctor. The recommended dose can vary based on your individual needs and the severity of your condition. Typically, the starting dose is one tablet daily, and your doctor may adjust it after 2-4 weeks based on your blood pressure response. It is crucial to take the tablet at the same time each day to maintain consistent medication levels in your body. It can be taken with or without food. Do not crush, chew, or break the tablet.

What are the possible side effects of NEBISTAR T TABLET?

Common side effects may include headache, dizziness, fatigue, a slower-than-usual heart rate (bradycardia), low blood pressure (hypotension), diarrhea, nausea, and swelling in the feet and ankles (peripheral oedema). Some individuals might also experience cold extremities or numbness/tingling. Less common but potentially serious side effects can include allergic reactions, shortness of breath, or worsening of heart failure. It is advised to avoid potassium-rich foods and supplements while taking this medicine as it may increase potassium levels in the blood.

Is NEBISTAR T TABLET safe during pregnancy or breastfeeding?

NEBISTAR T TABLET is generally not recommended and is contraindicated during pregnancy as it can potentially harm the unborn child. If you are pregnant or planning to conceive, you should discuss this with your doctor before starting this medication, and treatment should be discontinued if pregnancy is detected. It is also not recommended during breastfeeding, as components of the medicine can pass into breast milk. Always consult your doctor for advice if you are breastfeeding.

Can NEBISTAR T TABLET be taken with other medications?

It is important to inform your doctor about all other medications, supplements, and herbal remedies you are currently taking or plan to take, as certain medications can interact with NEBISTAR T TABLET. For instance, medications like quinidine, fluoxetine, and paroxetine can increase the levels of nebivolol in your body. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) might reduce the blood pressure-lowering effect. If you are taking antidiabetic agents, your doctor may need to adjust the dosage as beta-blockers can mask symptoms of low blood sugar. Other interacting medications include calcium channel blockers, other blood pressure-lowering drugs, and heart medications like digoxin. Avoid potassium supplements as telmisartan can increase blood potassium levels. It is also advisable to limit or avoid alcohol consumption while taking this medicine.

What precautions should be taken while using NEBISTAR T TABLET?

Do not stop taking NEBISTAR T TABLET suddenly or miss doses without consulting your doctor, as this can lead to a sudden increase in blood pressure or worsen your condition. Regular monitoring of your blood pressure is crucial. Inform your doctor if you have pre-existing medical conditions such as heart problems (including heart failure or a slow heartbeat), kidney or liver disease, diabetes, thyroid disorders, or low blood pressure. Since this medicine can cause dizziness, avoid driving or operating machinery if you feel dizzy, and rise slowly from a sitting or lying position. Caution is also advised if you are planning to undergo surgery.

What happens if a dose of NEBISTAR T TABLET is missed?

If you miss a dose of NEBISTAR T TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should NEBISTAR T TABLET be stored?

NEBISTAR T TABLET should be stored in a cool, dry place, away from direct sunlight. The ideal storage temperature is typically below 30°C or at room temperature. Keep this medicine out of the sight and reach of children. Always check the expiry date before use and do not use the tablets if they are past their expiration date.