Human Mixtard 30/100 Iu
Not Available
Source ID: 251949
₹545.71
₹440.06
(Inclusive of all taxes)Batch
RT6JW23
PKG
10 ML
Expiry
2027-10-31
MRP
₹545.71
Stock
1
Discount
19.36%
Description
HUMAN MIXTARD 30/100 IU by NOVO NORDISK
HUMAN MIXTARD 30/100 IU is a biphasic insulin preparation manufactured by Novo Nordisk, designed to help manage blood sugar levels in individuals with diabetes. It combines a fast-acting insulin with an intermediate-acting insulin to provide both rapid and sustained glucose control.
Composition
- Active Ingredients: Each milliliter of the suspension contains 100 International Units (IU) of human insulin, which is a blend of 30% soluble insulin (rapid-acting) and 70% isophane insulin (NPH, intermediate-acting). Human insulin is produced using recombinant DNA technology.
- Excipients: Includes zinc chloride, glycerol, metacresol, phenol, disodium phosphate dihydrate, sodium hydroxide/hydrochloric acid (for pH adjustment), protamine sulphate, and water for injections.
Uses
HUMAN MIXTARD 30/100 IU is prescribed for the treatment of:
- Type 1 Diabetes Mellitus
- Type 2 Diabetes Mellitus This medicine works by facilitating the uptake of glucose into muscle and fat cells and inhibiting glucose production by the liver, thereby lowering blood sugar.
Dosage and Administration
- Administration: Administered as a subcutaneous injection, typically in the thigh, abdominal wall, gluteal region, or deltoid region. Injection sites should be rotated within the chosen area to minimize the risk of lipodystrophy. It should never be administered intravenously.
- Dosage: Dosing is individualized based on the patient's needs, usually ranging from 0.3 to 1.0 IU/kg/day.
- Timing: Typically given once or twice daily, 30 minutes before a meal or snack containing carbohydrates, to ensure a rapid initial effect followed by a prolonged action.
- Preparation: Before injection, the suspension should be gently rolled between the hands until it appears uniformly white and cloudy.
Side Effects
- Common Side Effects: Hypoglycemia (low blood sugar), injection site reactions (such as pain, redness, itching, swelling), weight gain, peripheral oedema (swelling in the limbs), skin rash, and lipodystrophy (thickening or hollowing of the skin at the injection site).
- Serious Side Effects (Rare): Severe systemic allergic reactions (e.g., generalized rash, sweating, gastrointestinal upset, angioedema, breathing difficulties, rapid heartbeat, dizziness) are rare but potentially life-threatening and require immediate medical attention.
Precautions
- Hypoglycemia: Patients should regularly monitor blood glucose levels. Hypoglycemia can impair the ability to drive or operate machinery.
- Allergies: Do not use if there is a known allergy to human insulin or any of the excipients.
- Pregnancy and Breastfeeding: Consultation with a doctor is advised. Insulin treatment is generally considered safe during pregnancy with close monitoring and can be continued during breastfeeding as insulin does not pass into breast milk in significant amounts.
- Alcohol Consumption: Alcohol may affect blood glucose levels and interfere with the insulin's effects.
- Organ Impairment: Use with caution in patients with liver or kidney problems, as dose adjustments may be necessary.
- Insulin Changes: Switching between types or brands of insulin should only be done under strict medical supervision and may require dosage adjustments.
- Other Warnings: Never share insulin pens or needles. Do not use if the suspension is not uniformly white and cloudy, or if the cartridge or device appears damaged or has been frozen. HUMAN MIXTARD 30/100 IU is not for use in insulin infusion pumps.
Storage
- Before Opening: Store in a refrigerator between 2°C and 8°C. Do not freeze.
- In Use (or as a Spare): The product can be stored at room temperature (below 25°C or 30°C, depending on the specific formulation) for a maximum of 4 to 6 weeks. Do not refrigerate or freeze once in use. Keep the vial or pen in the outer carton to protect it from light.
₹545.71
₹440.06
(Inclusive of all taxes)Frequently Asked Questions
HUMAN MIXTARD 30/100 IU by NOVO NORDISK is a pre-mixed insulin product containing 30% soluble (rapid-acting) human insulin and 70% isophane (intermediate-acting) human insulin. It is used to manage blood sugar levels in people with diabetes.
What is HUMAN MIXTARD 30/100 IU used for?
HUMAN MIXTARD 30/100 IU is used for the treatment of diabetes mellitus, including both Type 1 and Type 2 diabetes, in adults and children. It helps to improve blood sugar control by maintaining glucose levels throughout the day.
How does HUMAN MIXTARD 30/100 IU work?
This medicine combines two types of human insulin: a short-acting insulin and an intermediate-acting insulin. The short-acting component (30% soluble insulin) works quickly to lower blood sugar levels after meals, while the intermediate-acting component (70% isophane insulin) provides a more prolonged effect, helping to maintain stable blood sugar levels between meals and overnight. It facilitates the uptake of glucose into muscle and fat cells and suppresses glucose production in the liver.
What is the usual dosage of HUMAN MIXTARD 30/100 IU?
The dosage of HUMAN MIXTARD 30/100 IU is individualized and determined by a doctor based on the patient's specific needs. Generally, the insulin requirement is between 0.3 and 1.0 International Units (IU) per kilogram of body weight per day. It is typically administered once or twice daily, usually 30 minutes before a meal containing carbohydrates.
What are the possible side effects of HUMAN MIXTARD 30/100 IU?
The most common side effect is hypoglycemia (low blood sugar), which can cause symptoms like lightheadedness, dizziness, anxiety, nervousness, tiredness, hunger, shaking, sweating, and pale skin. Other possible side effects include injection site reactions (pain, redness, swelling, itching), weight gain, rash, and edema (swelling due to fluid retention). Rarely, more severe allergic reactions can occur.
Is HUMAN MIXTARD 30/100 IU safe during pregnancy or breastfeeding?
HUMAN MIXTARD 30/100 IU is generally considered safe for use during pregnancy if prescribed by a doctor, but intensified blood glucose control and monitoring are recommended. Insulin does not pass the placental barrier. It is also likely safe to use during breastfeeding, and insulin treatment for the nursing mother poses no risk to the infant. However, the dose, diet, or both may need adjustment.
Can HUMAN MIXTARD 30/100 IU be taken with other medications?
HUMAN MIXTARD 30/100 IU can interact with certain medications that affect glucose metabolism. Some medicines, such as oral antidiabetic drugs, ACE inhibitors, and certain beta-blockers, may enhance its glucose-lowering effects. Other medications, including oral contraceptives, thiazides, glucocorticoids, and thyroid hormones, may increase insulin requirements. Alcohol consumption is generally unsafe as it can intensify or reduce the hypoglycemic effect. Always inform your doctor about all current medications you are taking.
What precautions should be taken with HUMAN MIXTARD 30/100 IU?
Monitor blood glucose levels regularly to avoid hypoglycemia or hyperglycemia. Rotate injection sites within the same region (e.g., abdomen, thigh, buttocks, or upper arm) to prevent skin changes like lipodystrophy (skin thickening or hollowing). Do not stop taking the medicine without consulting your doctor. Exercise caution when driving or operating machinery, as blood sugar fluctuations can impair concentration. Inform your doctor if you have kidney, liver, or heart problems, or thyroid disorders.
What happens if a dose is missed?
If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate, as this can lead to a drastic and dangerous fall in blood glucose. Monitor your blood sugar closely.
How should HUMAN MIXTARD 30/100 IU be stored?
Unopened HUMAN MIXTARD 30/100 IU should be stored in a refrigerator at 2°C to 8°C. Do not freeze it. Once in use or carried as a spare, it can be stored at room temperature (below 25°C or 30°C depending on the specific product presentation) for a maximum of 6 weeks. Keep it in the outer carton to protect it from light and excessive heat.