Sitara M 50/1000 Mg Tablet ( 10 Tablet )

SITARA M 50/1000 MG TABLET

SITARA M 50/1000 MG TABLET, manufactured by INTAS PHARMACEUTICALS LTD., is a combination medication used for the management of Type 2 Diabetes Mellitus.

• Name:
  • Brand Name: SITARA M 50/1000 MG TABLET (also referred to as Sitara-M 50/1000 Tablet ER).
• Composition:
  • Each tablet contains:
    • Sitagliptin: 50 mg
    • Metformin: 1000 mg
• Uses: SITARA M 50/1000 MG TABLET is prescribed to control high blood sugar levels in adults with Type 2 Diabetes Mellitus when diet and exercise alone are insufficient. It helps to prevent severe complications associated with diabetes, such as kidney damage, blindness, heart attacks, and strokes. The medication works by increasing insulin production by the pancreas, improving insulin sensitivity, and reducing glucose production by the liver.
• Dosage and Administration: This medicine should be taken exactly as prescribed by a doctor, often with meals to minimize stomach upset. It is generally taken regularly at the same time each day for optimal benefit and should not be stopped without consulting a doctor. Tablets should be swallowed whole and not crushed or chewed.
• Side Effects:
  • Common Side Effects: Diarrhea, nausea, vomiting, headache, sore throat, decreased appetite, upper respiratory tract infection, abdominal bloating, runny nose, and low blood sugar (hypoglycemia), especially when used with other diabetes medications.
  • Serious Side Effects: Lactic acidosis (a rare but serious condition that can harm the liver and kidneys), and potential Vitamin B12 deficiency with long-term use.
• Precautions: Before taking SITARA M 50/1000 MG TABLET, inform your doctor about any existing kidney, liver, or heart conditions, problems with the pancreas, or a history of pancreatitis. It is contraindicated in patients with Type 1 diabetes, diabetic ketoacidosis, severe kidney impairment, or liver impairment. Caution is advised for pregnant or breastfeeding individuals, and medical advice should be sought. Alcohol consumption should be avoided as it can increase the risk of lactic acidosis and lower blood glucose. Inform your doctor about all other medications you are taking to avoid potential drug interactions.
• Storage: Store SITARA M 50/1000 MG TABLET in a cool and dry place, away from direct sunlight, and out of the sight and reach of children. The typical storage temperature is below 30°C.

SITARA M 50/1000 MG TABLET is a combination medication used to manage Type 2 Diabetes Mellitus. It contains two active ingredients: Sitagliptin (50 mg) and Metformin (1000 mg). This medication helps control high blood sugar levels when diet and exercise alone are not sufficient.

What is SITARA M 50/1000 MG TABLET used for?

SITARA M 50/1000 MG TABLET is primarily used to manage high blood sugar levels in adults with Type 2 Diabetes Mellitus. By effectively controlling blood sugar, it helps prevent serious complications associated with diabetes, such as kidney damage, vision loss (retinopathy), nerve damage (neuropathy), heart attacks, and strokes.

How does SITARA M 50/1000 MG TABLET work?

This medication combines two different drugs, Sitagliptin and Metformin, which work together to control blood sugar.

• Sitagliptin (a DPP-4 inhibitor) works by increasing the levels of natural substances called incretins, which help the pancreas produce more insulin, especially after meals, and reduce the amount of sugar produced by the liver.
• Metformin (a biguanide) primarily works by reducing glucose production in the liver, delaying the absorption of glucose from the intestines, and increasing the body's sensitivity to insulin.

What is the usual dosage for SITARA M 50/1000 MG TABLET?

SITARA M 50/1000 MG TABLET is typically taken orally twice daily with meals to help reduce stomach upset. Your doctor will determine the appropriate dose based on your medical condition and blood sugar control. It is crucial not to exceed the maximum daily dose, which is generally not more than 100 mg of Sitagliptin and 2000 mg of Metformin.

What are the possible side effects of SITARA M 50/1000 MG TABLET?

Common side effects can include diarrhea, nausea, vomiting, stomach upset/pain, headache, upper respiratory tract infection, sore throat, and a metallic taste in the mouth. Low blood sugar (hypoglycemia) is also possible, especially when taken with other diabetes medications. Serious, though rare, side effects may include lactic acidosis (a build-up of lactic acid in the blood), pancreatitis (inflammation of the pancreas), and severe allergic reactions such as rash, hives, or swelling of the face, lips, tongue, or throat. Long-term use can also lead to Vitamin B12 deficiency.

Is SITARA M 50/1000 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: Caution is advised during pregnancy. This medicine should only be used if the potential benefit to the mother justifies any potential risk to the baby. It is important to consult your doctor before taking this medication if you are pregnant or planning a pregnancy. Breastfeeding: SITARA M 50/1000 MG TABLET is likely unsafe during breastfeeding. Limited data suggests the drug may pass into breast milk and could harm the baby. Always consult your doctor if you are breastfeeding.

Can SITARA M 50/1000 MG TABLET be taken with other medications?

SITARA M 50/1000 MG TABLET can interact with other medications. It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking.

• Taking it with insulin or other antidiabetic medicines can increase the risk of low blood sugar (hypoglycemia).
• Diuretics (like furosemide) and cationic medicines (like digoxin, morphine, vancomycin) may alter the effectiveness of metformin or increase the risk of lactic acidosis.
• Calcium channel blockers (like nifedipine) and corticosteroids may affect blood glucose levels.

What precautions should be taken while using SITARA M 50/1000 MG TABLET?

This medication is not suitable for individuals with Type 1 Diabetes or diabetic ketoacidosis. It should be avoided in patients with severe kidney or liver impairment and congestive heart failure. Inform your doctor if you have a history of pancreatitis or low vitamin B12 levels. Alcohol consumption should be avoided as it increases the risk of lactic acidosis. Your doctor will regularly monitor your blood sugar levels and kidney function during treatment. Also, inform your doctor before any major surgery or diagnostic tests involving contrast dyes, as the medication may need to be temporarily stopped.

What happens if a dose of SITARA M 50/1000 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should SITARA M 50/1000 MG TABLET be stored?

Store SITARA M 50/1000 MG TABLET at room temperature, ideally not above 30°C. Keep it in a cool, dry place, away from direct sunlight and heat. Ensure it is kept out of the reach of children and pets.