Dapacose 10 Mg Tablet (10 Tab)

DAPACOSE 10 MG TABLET is a prescription medication manufactured by J.B. Chemicals & Pharmaceuticals Ltd.

Name

• Brand Name: DAPACOSE 10 TABLET
• Common Name: Dapagliflozin 10 mg

Composition

Each tablet contains Dapagliflozin 10 mg as the active ingredient. Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor.

Uses

DAPACOSE 10 MG TABLET is primarily used for the management of:

• Type 2 Diabetes Mellitus: It helps control high blood sugar levels in adults and children aged 10 years and older, in conjunction with diet and exercise. It works by increasing glucose excretion through urine.
• Heart Failure: It is used in adults to reduce the risk of hospitalization due to heart failure.
• Chronic Kidney Disease: It helps slow the progression of chronic kidney disease in adults with reduced kidney function. Additionally, it may contribute to moderate weight loss and lower blood pressure in some individuals with type 2 diabetes.

Dosage and Administration

The typical adult dose is 10 mg once daily. It can be taken orally with or without food, preferably at the same time each day. The tablet should be swallowed whole; do not crush, chew, or break it. For elderly patients or those with reduced kidney function, close monitoring and potential dosage adjustments are advised. If a dose is missed, take it as soon as remembered unless it's almost time for the next dose.

Side Effects

Common side effects may include:

• Genital fungal infections (e.g., thrush, vaginal yeast infections, yeast infections of the penis)
• Urinary tract infections (UTIs)
• Increased urination frequency
• Back pain
• Dizziness
• Skin rash
• Dehydration, thirst
• Constipation, dry mouth
• Nausea, vomiting, nasopharyngitis (inflammation of the nasal passages and throat) Serious but rare side effects can include ketoacidosis or acute kidney injury.

Precautions

• Allergies: Do not take if allergic to Dapagliflozin or any other components of the medicine.
• Kidney/Liver Conditions: Inform your doctor about any existing kidney or liver problems. It is not recommended for patients on dialysis or with severe kidney issues.
• Pregnancy and Breastfeeding: Not recommended during pregnancy, especially in the second and third trimesters, or while breastfeeding. Consult a doctor.
• Dehydration: DAPACOSE may cause increased urination and dehydration. Ensure adequate fluid intake.
• Hypoglycemia: If taken with other antidiabetic medicines, alcohol, or if meals are skipped, it may cause low blood sugar. Carry sugary food or fruit juice to counteract symptoms.
• Alcohol Consumption: Avoid or limit alcohol while on this medication.
• Driving: Exercise caution when driving or operating machinery if experiencing dizziness or blood sugar fluctuations.
• Type 1 Diabetes: This medication is not for the treatment of type 1 diabetes or diabetic ketoacidosis.
• Hygiene: Maintain good personal hygiene to reduce the risk of genital and urinary tract infections.

Storage

Store DAPACOSE 10 MG TABLET in a cool, dry place between 15°C and 30°C (or below 30°C). Keep the medicine in its original packaging, protected from moisture, direct sunlight, and air exposure. Keep out of sight and reach of children and pets.

DAPACOSE 10 MG TABLET contains Dapagliflozin 10 mg as its active ingredient and is manufactured by J.B. Chemicals & Pharmaceuticals Ltd. It is primarily used to manage various conditions, including type 2 diabetes mellitus, heart failure, and chronic kidney disease.

Here are some frequently asked questions about DAPACOSE 10 MG TABLET:

What is DAPACOSE 10 MG TABLET used for?

DAPACOSE 10 MG TABLET is prescribed to manage type 2 diabetes mellitus in adults and children aged 10 years or older, especially when diet and exercise alone do not adequately control blood glucose levels. It is also used in adults for the management of heart failure and chronic kidney disease, helping to reduce the risk of hospitalization for heart failure and slow the progression of kidney damage. Additionally, it may contribute to moderate weight loss in patients with type 2 diabetes.

How does DAPACOSE 10 MG TABLET work?

DAPACOSE 10 MG TABLET contains Dapagliflozin, which belongs to a class of medicines called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It works by blocking the reabsorption of glucose in the kidneys, leading to increased excretion of glucose, sodium, and water from the body through urine. This process effectively lowers blood sugar levels, reduces the workload on the heart, and protects kidney function.

What is the usual dosage for DAPACOSE 10 MG TABLET?

For adults and elderly patients, the standard dose is typically 10 mg once daily. It can be taken with or without food, usually in the morning. In some cases, for children aged 10 years and older with type 2 diabetes, the starting dose is also 10 mg daily. Your doctor will determine the appropriate dose based on your individual condition and response to the medication.

What are the possible side effects of DAPACOSE 10 MG TABLET?

Common side effects may include fungal infections of the genitals (thrush), urinary tract infections (UTIs), increased urination, back pain, dizziness, skin rash, dehydration, thirst, constipation, and dry mouth. It is important to stay well-hydrated to counteract dehydration. If any side effects worsen or become persistent, it is advisable to contact your physician. In rare cases, more serious conditions like diabetic ketoacidosis or acute kidney injury can occur.

Is DAPACOSE 10 MG TABLET safe during pregnancy or breastfeeding?

DAPACOSE 10 MG TABLET is generally not recommended during pregnancy, especially in the second and third trimesters, as its safety has not been established and animal studies suggest potential harm to kidney development in unborn babies. Similarly, it is not recommended during breastfeeding as it is unknown if the medicine passes into human milk. Always consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Can DAPACOSE 10 MG TABLET be taken with other medications?

DAPACOSE 10 MG TABLET can be taken with other antidiabetic medications like metformin or insulin, but dosage adjustments may be necessary. It can interact with diuretics (water pills), potentially leading to excessive fluid loss and low blood pressure. It's crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid possible interactions.

What precautions should be taken while using DAPACOSE 10 MG TABLET?

Before taking DAPACOSE 10 MG TABLET, inform your doctor if you have any liver or kidney problems, severe low blood pressure, or are severely dehydrated due to excessive vomiting or diarrhea. Patients with type 1 diabetes should not use this medication due to an increased risk of diabetic ketoacidosis. Maintaining good personal hygiene is important to reduce the risk of genital fungal and urinary tract infections. Alcohol consumption should be limited or avoided as it may lead to high or low blood sugar levels and increase the risk of dehydration or lactic acidosis.

What happens if a dose of DAPACOSE 10 MG TABLET is missed?

If you miss a dose of DAPACOSE 10 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may lead to low blood sugar or dehydration.

How should DAPACOSE 10 MG TABLET be stored?

DAPACOSE 10 MG TABLET should be stored at room temperature, typically between 15°C and 30°C (59°F and 86°F), in a cool, dry place. Keep the tablets in their original packaging (blister pack or bottle) to protect them from moisture, direct sunlight, and air exposure. Always keep the medication out of the sight and reach of children and pets.