Dapanova Sm 1000 Tab

DAPANOVA SM 1000 Tablet

Name: Dapanova SM 1000 Tablet (Brand name)

Composition: DAPANOVA SM 1000 Tablet contains a combination of three active ingredients: Dapagliflozin (10 mg), Metformin (1000 mg), and Sitagliptin (100 mg).

Uses: DAPANOVA SM 1000 Tablet is an antidiabetic medicine primarily used in the management of Type 2 Diabetes Mellitus in adults. It is prescribed as an adjunct to diet and exercise to improve blood sugar control, especially when conventional therapies are insufficient. Beyond glycemic control, it also contributes to cardiovascular and kidney protection by lowering the risk of heart failure and diabetic kidney disease. This medication also supports weight loss and metabolic control.

Dosage and Administration: Take DAPANOVA SM 1000 Tablet as advised by your doctor. The tablet should be swallowed whole with water, without chewing, crushing, or breaking it. It can be taken with or without food, but it is recommended to take it at the same time each day for consistent results. Do not exceed the prescribed dose or stop taking the medicine without consulting your doctor.

Side Effects: Common side effects may include:

• Vomiting, nausea, abdominal pain, stomach upset
• Headache
• Female genital mycotic infections
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Urinary tract infections
• Diarrhea

Serious but rare side effects can include lactic acidosis (weakness, breathing difficulty, stomach pain) and ketoacidosis (nausea, vomiting, confusion, fruity breath). Pancreatitis, painful or persistent genital/urinary infections, and allergic reactions (rash, swelling, breathing problems) also require prompt medical attention.

Precautions:

• Inform your doctor about any medical history, including kidney or liver problems, urinary tract infections, or if you are on water pills (diuretics).
• Not recommended for use in children below 18 years of age.
• Avoid excessive alcohol intake during treatment due to an increased risk of side effects like lactic acidosis.
• Consult your doctor if you are pregnant or breastfeeding.
• Caution is advised with certain medications such as thiazide and loop diuretics, and carbonic anhydrase inhibitors, as they can increase the risk of lactic acidosis or dehydration.
• Patients with severe renal impairment, hepatic impairment, or diabetic ketoacidosis should avoid this medicine.

Storage: Store DAPANOVA SM 1000 Tablet in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. The medicine should be stored at temperatures between 10ºC to 25ºC or below 30ºC.

DAPANOVA SM 1000 TAB is a combination medication containing three active ingredients: Dapagliflozin, Sitagliptin, and Metformin. This medicine is used to manage type 2 diabetes mellitus in adults.

Here are some frequently asked questions about DAPANOVA SM 1000 TAB:

What is DAPANOVA SM 1000 TAB used for?

DAPANOVA SM 1000 TAB is primarily used as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Additionally, it may be used to lower the risk of hospitalization for heart failure and to reduce the risk of worsening kidney disease in certain patients with type 2 diabetes.

How does DAPANOVA SM 1000 TAB work?

This medicine combines three different mechanisms to lower blood sugar levels:

• Dapagliflozin: An SGLT2 inhibitor that works by causing the kidneys to remove excess glucose from the body through urine.
• Sitagliptin: A DPP-4 inhibitor that increases the levels of certain natural substances (incretins) which help the pancreas release more insulin when blood sugar levels are high and decrease sugar production by the liver.
• Metformin: A biguanide that reduces the amount of sugar produced by the liver, decreases the absorption of sugar from the intestines, and improves the body's sensitivity to insulin.

What is the usual dosage of DAPANOVA SM 1000 TAB?

The specific dosage of DAPANOVA SM 1000 TAB should be determined by your doctor based on your individual medical condition and response to treatment. It is typically taken once daily with food. Tablets should be swallowed whole and not crushed, cut, or chewed. It's crucial not to exceed the recommended dose.

What are the possible side effects of DAPANOVA SM 1000 TAB?

Common side effects may include:

• Genital fungal infections (female and male)
• Urinary tract infections (UTIs)
• Diarrhea
• Nausea and vomiting
• Headache
• Nasopharyngitis (inflammation of the nose and throat)

Serious, though less common, side effects requiring immediate medical attention include:

• Lactic acidosis: Symptoms include muscle pain or cramps, stomach pain, trouble breathing, unusual tiredness, and feeling generally unwell.
• Diabetic ketoacidosis (DKA): Symptoms include increased thirst/urination, dry mouth, fatigue, fruity odor to breath, trouble breathing, and stomach pain.
• Severe allergic reactions (skin rash, itching, hives, swelling of the face, lips, tongue, or throat).
• Dehydration, leading to dizziness, lightheadedness, or feeling faint.

Is DAPANOVA SM 1000 TAB safe during pregnancy or breastfeeding?

DAPANOVA SM 1000 TAB is generally not recommended during pregnancy due to limited information on its use and potential risks to the fetus. Other diabetes medicines, like insulin and metformin, may be considered safer alternatives during pregnancy. For breastfeeding, the manufacturer does not recommend dapagliflozin due to a theoretical risk to the infant's developing kidney, although it's unlikely to pass into breast milk in clinically significant amounts. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can DAPANOVA SM 1000 TAB be taken with other medications?

It's important to inform your doctor about all medications, supplements, and herbal products you are taking. DAPANOVA SM 1000 TAB can interact with several medications:

• Insulin or sulfonylureas: Concomitant use can increase the risk of low blood sugar (hypoglycemia). Your doctor may need to adjust the dosage of these medications.
• Diuretics (water pills): May increase the risk of dehydration and low blood pressure.
• Carbonic anhydrase inhibitors: May increase the risk of lactic acidosis.
• Alcohol: Drinking alcohol can increase the risk of lactic acidosis and hypoglycemia.
• Certain antibiotics, blood pressure medications, and mental health medications can also affect blood sugar levels.

What precautions should be taken while taking DAPANOVA SM 1000 TAB?

• Kidney and Liver Function: Inform your doctor if you have kidney or liver disease, as this medicine may not be suitable or may require dose adjustments.
• Dehydration: Drink plenty of fluids to prevent dehydration, especially in hot weather, during exercise, or if you experience vomiting or diarrhea. Dehydration can lead to serious kidney damage.
• Surgery or Medical Procedures: You may need to stop taking this medicine before certain surgeries or imaging tests involving iodinated contrast agents. Discuss this with your doctor.
• Symptoms of Lactic Acidosis/Ketoacidosis: Be aware of the symptoms and seek immediate medical attention if they occur.
• Vitamin B12 levels: Long-term use of metformin may lead to low vitamin B12 levels, so your doctor may monitor these.
• Allergies: Do not take this medicine if you have a known allergy to dapagliflozin, sitagliptin, metformin, or any other ingredients.
• Type 1 Diabetes: This medicine is not for type 1 diabetes or diabetic ketoacidosis.

What happens if a dose is missed?

If you miss a dose of DAPANOVA SM 1000 TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should DAPANOVA SM 1000 TAB be stored?

Store DAPANOVA SM 1000 TAB in a closed container at room temperature, generally between 20 and 25 degrees C (68 and 77 degrees F), away from heat, moisture, and direct light. Keep it out of the reach of children and pets. Properly dispose of any outdated or unused medicine.