Hefcard 50 Mg Tablet (14 Tab)

HEFCARD 50 MG TABLET, manufactured by Torrent Pharmaceuticals Ltd., is a medication used in the management of heart failure.

Name

• Brand Name: HEFCARD 50 MG TABLET
• Common Name: Sacubitril and Valsartan

Composition

HEFCARD 50 MG TABLET contains a combination of two active ingredients:

• Sacubitril 24 mg
• Valsartan 26 mg This combination belongs to a class of drugs known as Angiotensin Receptor-Neprilysin Inhibitors (ARNIs).

Uses

HEFCARD 50 MG TABLET is primarily prescribed for the treatment of chronic heart failure with reduced ejection fraction (HFrEF) in adults. It helps to reduce the risk of cardiovascular death and hospitalization in patients with chronic heart failure. The medication works by relaxing and widening blood vessels, making it easier for the heart to pump blood, and by reducing fluid retention in the body.

Dosage and Administration

• HEFCARD 50 MG TABLET should be taken exactly as prescribed by your physician.
• Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
• It can be taken with or without food.
• For optimal benefits, maintain consistency by taking it at the same time each day.
• Do not exceed the recommended dose.

Side Effects

Common side effects may include:

• Dizziness, headache
• Cough
• Nausea, diarrhea
• Weakness, fatigue
• Low blood pressure (hypotension)
• Increased potassium levels in the blood (hyperkalemia)
• Impaired renal function (kidney dysfunction)

Serious side effects, though rare, can include angioedema (swelling of the face, lips, tongue, or throat, which may cause difficulties in breathing or swallowing).

Precautions

• HEFCARD 50 MG TABLET is contraindicated during pregnancy and is not recommended for breastfeeding women.
• Avoid use if you have a known allergy to sacubitril, valsartan, or have a history of angioedema.
• Use with caution if you have kidney or liver diseases; it is contraindicated in severe liver disease.
• Inform your doctor if you are taking other medications, especially ACE inhibitors (a 36-hour wash-out period is required before or after taking an ACE inhibitor) or aliskiren (particularly if you have diabetes or kidney impairment).
• Regular monitoring of blood pressure, kidney function, and potassium levels is essential during treatment.
• Avoid alcohol consumption as it may excessively lower blood pressure.
• Limit intake of potassium supplements and potassium-rich foods to prevent elevated potassium levels.

Storage

• Store in a cool and dry place, away from direct sunlight.
• Keep the tablets in their original packaging to protect them from moisture.
• Store at room temperature, ideally below 30°C.
• Keep out of the sight and reach of children.

Here are some frequently asked questions about HEFCARD 50 MG TABLET:

What is HEFCARD 50 MG TABLET used for?

HEFCARD 50 MG TABLET is primarily used in adults for the treatment of chronic heart failure with reduced ejection fraction (HFrEF), a condition where the heart cannot pump blood effectively. It helps to reduce the risk of cardiovascular death and hospitalisation due to heart failure. It can also be used in children above one year of age for heart failure.

How does HEFCARD 50 MG TABLET work?

HEFCARD 50 MG TABLET is a combination of two medicines: sacubitril and valsartan. Sacubitril inhibits an enzyme called neprilysin, which helps increase the levels of beneficial peptides that relax blood vessels. Valsartan is an angiotensin receptor blocker (ARB) that blocks the effect of angiotensin II, a substance that constricts blood vessels. Together, these actions relax and widen blood vessels, reduce strain on the heart, improve heart function, and help the body retain less water, making it easier for the heart to pump blood.

What is the usual dosage of HEFCARD 50 MG TABLET?

The dosage of HEFCARD 50 MG TABLET is determined by your doctor based on the severity of your condition and your response to treatment. It should be taken exactly as prescribed by your physician, usually at the same time each day, with or without food. The tablet should be swallowed whole with a glass of water and not crushed or chewed.

What are the possible side effects of HEFCARD 50 MG TABLET?

Common side effects may include dizziness, light-headedness (low blood pressure), cough, high potassium levels (hyperkalemia), kidney dysfunction, headache, fatigue, nausea, and diarrhea. Serious side effects like angioedema (swelling of the face, lips, tongue, or throat) can occur, and if experienced, immediate medical attention should be sought.

Is HEFCARD 50 MG TABLET safe during pregnancy or breastfeeding?

HEFCARD 50 MG TABLET is contraindicated during pregnancy, especially after the first three months, as it can cause serious harm to the unborn baby. It is also not recommended for use in breastfeeding women. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can HEFCARD 50 MG TABLET be taken with other medications?

HEFCARD 50 MG TABLET can interact with several medications. It should not be taken with ACE inhibitors (e.g., enalapril, lisinopril) or other angiotensin receptor blockers (ARBs) like losartan, as this can increase the risk of side effects like angioedema and low blood pressure. It is also contraindicated with aliskiren (a blood pressure-lowering medicine) in patients with diabetes or kidney disease. Concomitant use with potassium-sparing diuretics, potassium supplements, or NSAIDs can increase potassium levels or worsen kidney function. Always inform your doctor about all medicines, herbal preparations, and supplements you are currently taking.

What precautions should be taken while taking HEFCARD 50 MG TABLET?

Inform your doctor about any pre-existing medical conditions, especially kidney or liver diseases, low blood pressure, dehydration, or a history of angioedema. Regular monitoring of blood pressure, kidney function, and potassium levels is essential during treatment. Avoid alcohol consumption as it may worsen dizziness. Caution is advised when driving or operating machinery, as the medicine can cause dizziness or tiredness.

What happens if a dose of HEFCARD 50 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should HEFCARD 50 MG TABLET be stored?

HEFCARD 50 MG TABLET should be stored in a cool and dry place, away from direct sunlight. The temperature should ideally be below 30°C. Keep it in its original packaging to protect it from moisture and ensure it is kept out of the sight and reach of children.