Voage 10 Mg Tablet

VOAGE 10 MG TABLET by ALEMBIC PHARMACEUTICALS LTD

VOAGE 10 MG TABLET is a prescription medication manufactured by Alembic Pharmaceuticals Ltd. It is used in the management of Type 2 Diabetes Mellitus and also has applications in treating heart failure and chronic kidney disease.

Composition

The active ingredient in VOAGE 10 MG TABLET is Dapagliflozin 10 mg. This medication belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors.

Uses

VOAGE 10 MG TABLET is primarily used for:

• Type 2 Diabetes Mellitus: It helps to manage blood sugar levels in adults when diet and exercise alone are insufficient. It can be used alone or in combination with other antidiabetic medications.
• Heart Failure: It reduces the risk of hospitalization due to heart failure in adults, particularly those with Type 2 diabetes and cardiovascular disease or multiple risk factors.
• Chronic Kidney Disease (CKD): It slows down the progression of kidney disease in adults with reduced kidney function, including both diabetic and non-diabetic kidney disease.
• Weight Loss: It may also contribute to moderate weight loss in patients with Type 2 diabetes by promoting the loss of excess glucose through urine.

Dosage and Administration

The typical dosage for adults and elderly patients is 10 mg once daily, taken orally with or without food. It is important to take the tablet at the same time each day for consistent blood sugar control. The tablet should be swallowed whole and not chewed, crushed, or broken. In elderly patients or those with reduced kidney or moderate hepatic impairment, a lower starting dose (e.g., 5 mg daily) and careful monitoring or dose adjustments may be required. VOAGE 10 MG TABLET is generally not recommended for children under 10 years of age.

Side Effects

Common side effects may include:

• Genital fungal infections (thrush), causing itching, irritation, unusual discharge, or odor.
• Urinary tract infections (UTIs).
• Increased urination frequency and volume (polyuria).
• Back pain.
• Dizziness.
• Dehydration, thirst, dry mouth.
• Nausea and vomiting.
• Nasopharyngitis (inflammation of the throat and nasal passages).

Serious but rare side effects can include ketoacidosis or acute kidney injury.

Precautions

• Allergies: Do not take if allergic to any components of the medicine.
• Kidney and Liver Conditions: Inform your doctor if you have kidney or liver problems, as dose adjustments or careful monitoring may be necessary.
• Dehydration and Blood Pressure: Use with caution if you have severe low blood pressure or are severely dehydrated, or are taking diuretics, as it can further lower blood pressure and increase the risk of dehydration.
• Pregnancy and Breastfeeding: Not recommended during pregnancy, especially the second and third trimesters, or while breastfeeding, as safety has not been established.
• Alcohol Consumption: Limit alcohol intake, as it may increase the risk of certain side effects or hypoglycemia.
• Hypoglycemia: Be aware of low blood sugar, especially when taken with other diabetes medications or alcohol, or if meals are skipped. Carry sugary snacks for emergencies.
• Hygiene: Maintain good hygiene to prevent genital fungal and urinary tract infections.
• Monitoring: Regular monitoring of blood sugar levels, kidney function, and hydration status is advised.
• Type 1 Diabetes: Contraindicated in patients with Type 1 diabetes.

Storage

Store VOAGE 10 MG TABLET at room temperature, typically between 15°C and 30°C, in a cool, dry place. Keep it in its original packaging (blister pack/bottle) and protect it from moisture, sunlight, and air exposure. Keep out of sight and reach of children and pets. Properly dispose of expired or unused tablets.

VOAGE 10 MG TABLET is a medication primarily used for the management of type 2 diabetes mellitus. Its active ingredient is Dapagliflozin (10 mg). This medicine is also used to reduce the risk of hospitalization due to heart failure and to slow down the progression of chronic kidney disease in adults.

Here are some frequently asked questions about VOAGE 10 MG TABLET:

What is VOAGE 10 MG TABLET used for?

VOAGE 10 MG TABLET is used to manage type 2 diabetes mellitus in adults when diet and exercise alone are insufficient to control blood sugar levels. It also helps in minimizing the risk of hospitalization due to heart failure in adults with type 2 diabetes and heart disease or risk factors. Furthermore, it is prescribed to slow down the progression of kidney disease in adults diagnosed with this condition.

How does VOAGE 10 MG TABLET work?

VOAGE 10 MG TABLET contains Dapagliflozin, which belongs to a class of medicines called SGLT2 inhibitors. It works by blocking a protein in your kidneys called sodium-glucose co-transporter 2 (SGLT2). This action prevents the reabsorption of glucose back into the body from the urine, leading to more glucose being expelled through urine. This effectively lowers blood sugar levels. It also helps protect kidney function and reduces the strain on the heart.

What is the usual dosage?

The usual dosage for adults and elderly patients is 10 mg once daily, taken with or without food, preferably at the same time each day. Your doctor may start with a lower dose (e.g., 5 mg daily) and adjust it based on your response, especially for elderly patients or those with liver or kidney impairment. Do not exceed the maximum recommended dose of 20 mg per day.

What are the possible side effects?

Common side effects of VOAGE 10 MG TABLET include genital yeast infections, urinary tract infections (UTIs), increased urination, back pain, dizziness, and rash. Other potential side effects include hypoglycemia (low blood sugar), dehydration, and thirst. In rare cases, more serious complications like diabetic ketoacidosis can occur. Most side effects are temporary and resolve as your body adjusts to the medication.

Is it safe during pregnancy or breastfeeding?

VOAGE 10 MG TABLET is generally not recommended during pregnancy as its safety and efficacy have not been established in this population. Animal studies have shown harmful effects on the developing baby. For breastfeeding women, the use of VOAGE 10 MG TABLET is not recommended as the effects on the infant are unknown. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can it be taken with other medications?

VOAGE 10 MG TABLET can interact with other medications. Taking it with diuretics (water pills) like furosemide or hydrochlorothiazide may increase the risk of dehydration and electrolyte imbalances. If taken with insulin or insulin secretagogues (like glipizide), dosage adjustments might be needed to reduce the risk of hypoglycemia. Always inform your doctor about all medicines, supplements, or herbals you are currently taking to avoid possible interactions.

What precautions should be taken?

Before taking VOAGE 10 MG TABLET, inform your doctor if you have kidney or liver problems, a history of recurrent genital or urinary tract infections, or low blood pressure. It's important to stay adequately hydrated to prevent dehydration, as this medicine increases urine output. Maintain good hygiene practices to reduce the risk of fungal infections. Avoid excessive alcohol consumption, as it can lower blood sugar levels and increase the risk of certain side effects.

What happens if a dose is missed?

If you miss a dose of VOAGE 10 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should it be stored?

VOAGE 10 MG TABLET should be stored at room temperature, typically below 30°C (or between 15°C and 30°C). Keep the medicine in its original packaging, protected from moisture and direct sunlight. Ensure it is out of sight and reach of children and pets.