Gluject-m 500 Tab

GLUJECT-M 500 Tablet by ABBOTT HEALTHCARE PVT. LTD.

Name

• Brand Name: GLUJECT-M 500 Tablet, GLUJECT-M 500 Tablet ER

Composition

• Each tablet contains Dapagliflozin (10 mg) and Metformin (500 mg). Dapagliflozin is an SGLT2 inhibitor, and Metformin is a biguanide.

Uses

• GLUJECT-M 500 Tablet is primarily used for the management of type 2 diabetes mellitus in adults when diet and exercise alone are insufficient to control blood sugar levels.
• It also helps reduce the risk of hospitalization due to heart failure in adults with type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors.

Dosage and Administration

• The medicine is typically taken once daily, preferably with meals, or as advised by a doctor.
• Tablets should be swallowed whole with a glass of water; do not crush, chew, or break them.
• Dosage may be adjusted by the doctor based on individual needs and response to treatment. It is important to take the medication at the same time each day for optimal control.

Side Effects

• Common: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, dehydration, genital mycotic infections, urinary tract infections, low blood pressure, sore throat, nasal congestion, runny nose, back pain, and increased urination.
• Serious: Lactic acidosis (symptoms include severe tiredness, muscle pain, difficulty breathing), and hypoglycemia (low blood sugar, especially when combined with other antidiabetic medicines).

Precautions

• Not recommended for use in type 1 diabetes mellitus or severe kidney or liver disease.
• Caution is advised with alcohol consumption due to an increased risk of lactic acidosis.
• Generally not recommended during pregnancy (especially second and third trimesters) or breastfeeding.
• Patients with renal impairment, heart failure, or a history of pancreatitis should exercise caution.
• Interactions may occur with diuretics, insulin/insulin secretagogues, carbonic anhydrase inhibitors, and cationic medicines. Not recommended for children and adolescents under 18 years.

Storage

• Store in a cool and dry place, away from direct sunlight, at a temperature below 30°C.
• Keep out of sight and reach of children.

GLUJECT-M 500 TAB is a medication primarily used in the management of type 2 diabetes mellitus. It combines two active ingredients, Dapagliflozin and Metformin, to help lower blood sugar levels and can also reduce the risk of hospitalization due to heart failure in certain adults with type 2 diabetes.

What is GLUJECT-M 500 TAB used for?

GLUJECT-M 500 TAB is used to manage type 2 diabetes mellitus in adults, particularly when diet and exercise alone are insufficient to control blood sugar levels. It also helps in reducing the risk of hospitalization for heart failure in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors.

How does GLUJECT-M 500 TAB work?

This medicine contains two active ingredients: Dapagliflozin and Metformin. Dapagliflozin (an SGLT2 inhibitor) works by causing the kidneys to excrete more glucose through the urine, thereby lowering blood glucose levels. Metformin (a biguanide) reduces the liver's production of glucose, decreases the absorption of glucose from the intestines, and improves the body's sensitivity to insulin, allowing cells to use glucose more efficiently.

What is the usual dosage for GLUJECT-M 500 TAB?

The exact dosage is determined by your doctor based on your medical condition and response to treatment. It is typically taken once or twice daily with meals. It's crucial to follow your doctor's instructions regarding the dosage and duration and never exceed the prescribed amount.

What are the possible side effects of GLUJECT-M 500 TAB?

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and a metallic taste in the mouth. Other common side effects can be genital mycotic infections, urinary tract infections (UTIs), increased urination, and dehydration. A serious but rare side effect is lactic acidosis, which requires immediate medical attention if symptoms like severe tiredness, muscle pain, or difficulty breathing occur.

Is GLUJECT-M 500 TAB safe during pregnancy or breastfeeding?

GLUJECT-M 500 TAB is generally not recommended during pregnancy, especially in the second and third trimesters, due to potential risks to the unborn baby. It is also not advised during breastfeeding, as its components may pass into breast milk. Always consult your doctor if you are pregnant, planning to conceive, or breastfeeding to discuss potential risks and alternative options.

Can GLUJECT-M 500 TAB be taken with other medications?

GLUJECT-M 500 TAB can interact with several other medications. Taking it with diuretics (e.g., furosemide) may increase the risk of dehydration and low blood pressure. Concomitant use with insulin or insulin secretagogues (like glipizide) can increase the risk of hypoglycemia (low blood sugar). It may also interact with carbonic anhydrase inhibitors, certain cationic medicines, and iodinated contrast agents used for X-rays. Inform your doctor about all medications, supplements, and herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using GLUJECT-M 500 TAB?

Before taking this medication, inform your doctor if you have kidney or liver disease, heart failure, or a history of pancreatitis. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis. Maintain good hygiene to prevent genital fungal infections, and stay well-hydrated to reduce the risk of urinary tract infections and dehydration. Regular monitoring of blood sugar levels is important, and you should inform your doctor if you are undergoing any X-ray procedures involving injectable dye.

What happens if a dose of GLUJECT-M 500 TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should GLUJECT-M 500 TAB be stored?

GLUJECT-M 500 TAB should be stored in a cool, dry place, typically below 30°C, away from direct sunlight and moisture. Keep it out of the sight and reach of children and pets.