Sitara M 100/1000 Tablet

SITARA M 100/1000 TABLET

SITARA M 100/1000 Tablet is an antidiabetic medication manufactured by Intas Pharmaceuticals Ltd., primarily used in the management of Type 2 Diabetes Mellitus.

Composition

Each tablet contains a combination of two active ingredients:

• Sitagliptin: 100 mg
• Metformin: 1000 mg (as Metformin Hydrochloride)

Uses

SITARA M 100/1000 Tablet is prescribed to improve blood glucose levels in adults with Type 2 Diabetes Mellitus, particularly when diet and exercise alone are insufficient. It works by helping the pancreas produce more insulin, improving the body's sensitivity to insulin, and reducing glucose production by the liver. Effective blood sugar control helps prevent serious diabetes-related complications such as kidney damage, eye damage, nerve problems, loss of limbs, heart attack, and stroke.

Dosage and Administration

The dosage of SITARA M 100/1000 Tablet is determined by a physician based on individual factors like blood glucose levels, overall health, and response to treatment. It is typically taken orally, once or twice daily, with meals to minimize gastrointestinal side effects. The tablet should be swallowed whole with water and not crushed, split, or chewed. For optimal benefits, it should be taken regularly at the same time each day, and treatment should not be stopped without consulting a doctor.

Side Effects

Common side effects may include:

• Diarrhea, nausea, vomiting, stomach pain/upset
• Headache, dizziness, fatigue, weakness
• Upper respiratory tract infection, sore throat
• Metallic taste, skin rash, itching

Serious, though rare, side effects include:

• Hypoglycemia (low blood sugar), especially when taken with other diabetes medications like insulin or sulfonylurea.
• Lactic acidosis, a serious condition characterized by increased lactic acid in the blood. Symptoms can include muscle pain, unusual tiredness, difficulty breathing, and stomach pain.
• Vitamin B12 deficiency with long-term use.

Precautions

Before taking SITARA M 100/1000 Tablet, inform your doctor about any pre-existing conditions, especially kidney, liver, or heart disease, pancreatic problems, or if you consume alcohol regularly. It is not suitable for Type 1 Diabetes, diabetic ketoacidosis, or severe kidney/liver impairment. Pregnant or breastfeeding women should consult their doctor. Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with SITARA M (e.g., insulin, diuretics). Regular monitoring of kidney function and blood sugar levels is recommended throughout treatment.

Storage

Store SITARA M 100/1000 Tablet at room temperature, away from moisture and heat. Keep it out of reach of children.

Here are frequently asked questions about SITARA M 100/1000 TABLET:

1. What is SITARA M 100/1000 TABLET used for?

SITARA M 100/1000 TABLET is primarily used to treat Type 2 diabetes mellitus in adults. It helps improve blood sugar control when used alongside a healthy diet and regular exercise. By managing blood sugar levels, it aims to reduce the risk of serious complications associated with diabetes, such as kidney damage, eye damage, nerve problems, heart attacks, and strokes.

2. How does SITARA M 100/1000 TABLET work?

This medication is a combination of two active ingredients: Sitagliptin (100mg) and Metformin (1000mg). Sitagliptin is a DPP-4 inhibitor that works by increasing the levels of natural substances called incretins, which in turn help the pancreas produce more insulin when blood sugar levels are high and decrease the amount of glucose produced by the liver. Metformin is a biguanide that reduces glucose production in the liver, delays glucose absorption from the intestines, and improves the body's sensitivity to insulin, allowing cells to use glucose more effectively. Together, these mechanisms help to lower and control blood sugar levels.

3. What is the usual dosage for SITARA M 100/1000 TABLET?

The recommended dosage of SITARA M 100/1000 TABLET is determined by your doctor based on your specific condition, blood sugar levels, and current medication regimen. It is typically prescribed to be taken orally, usually once or twice daily, with meals to minimize gastrointestinal side effects. It's crucial to adhere strictly to the prescribed dosage and timing and not to alter the dosage without consulting your doctor.

4. What are the possible side effects of SITARA M 100/1000 TABLET?

Common side effects may include decreased appetite, nausea, vomiting, diarrhea, stomach upset, headache, and upper respiratory tract infection. Hypoglycemia (low blood glucose level) is also a potential side effect, especially when taken with other diabetes medications. More serious but rare side effects can include lactic acidosis (which can present with muscle pain, rapid breathing, and severe weakness) and pancreatitis. It is important to familiarize yourself with the signs of hypoglycemia and how to manage it, and to seek immediate medical attention for severe reactions or signs of lactic acidosis or pancreatitis.

5. Is SITARA M 100/1000 TABLET safe during pregnancy or breastfeeding?

SITARA M 100/1000 TABLET is generally not recommended for use during pregnancy, and information regarding its safety is limited, though animal studies have shown harmful effects on developing babies. It is also probably unsafe to use during breastfeeding, as limited human data suggests it may enter breast milk. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding, as they will weigh the benefits against potential risks.

6. Can SITARA M 100/1000 TABLET be taken with other medications?

It is vital to inform your doctor about all other medications, supplements, and herbal products you are currently taking, as some may interact with SITARA M 100/1000 TABLET. Taking it with insulin or other antidiabetic medicines may increase the risk of hypoglycemia. Diuretics can increase the risk of lactic acidosis, and certain cationic medicines may interfere with metformin absorption or elimination. Your doctor needs this information to ensure your safety and adjust your treatment plan if necessary.

7. What precautions should be taken while using SITARA M 100/1000 TABLET?

Before starting this medication, inform your doctor about any history of kidney, liver, or heart issues, pancreatic problems, or alcohol consumption habits. Regular monitoring of kidney function and blood sugar levels is typically conducted throughout treatment. Alcohol consumption should be avoided as it can increase the risk of lactic acidosis and hypoglycemia. Use with caution in elderly patients, and inform your doctor if you are undergoing any surgery or diagnostic tests involving an X-ray contrast agent.

8. What happens if a dose of SITARA M 100/1000 TABLET is missed?

If you miss a dose of SITARA M 100/1000 TABLET, take it as soon as you remember. However, if it's nearly time for your next scheduled dose, it's best to skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects. Consistency in taking the medication at the same time each day is important for effective blood sugar control.

9. How should SITARA M 100/1000 TABLET be stored?

SITARA M 100/1000 TABLET should be stored at room temperature, typically not above 30°C, in a cool and dry place. It should be protected from moisture and light and kept out of the reach of children and pets.