Sgltd Trio 500mg Tab

SGLTD TRIO 500MG Tablet

SGLTD TRIO 500MG Tablet by Mankind Pharma Ltd. is a combination medication designed for the management of Type 2 Diabetes Mellitus. It aids in achieving better blood sugar control, especially in adults whose blood sugar levels are not adequately managed by metformin alone or dual therapy.

Composition

Each tablet contains a combination of three active ingredients:

• Dapagliflozin 10 mg
• Sitagliptin 100 mg
• Metformin 500 mg

Uses

SGLTD TRIO 500MG Tablet is primarily used to improve blood sugar control in adults with Type 2 Diabetes Mellitus as an adjunct to diet and exercise. It helps in the proper utilization of insulin and also offers additional benefits such as reducing the risk of cardiovascular events and protecting kidney function in some diabetic patients, as well as aiding in weight management.

Dosage and Administration

This medicine should be taken orally as advised by your doctor. It can be taken with or without food, but it is recommended to take it at the same time each day for optimal benefits. The tablet should be swallowed whole and not crushed, broken, or chewed. Do not exceed the prescribed dose or stop taking the medicine without consulting your doctor.

Side Effects

Common side effects may include:

• Nausea, vomiting, abdominal pain, stomach upset
• Headache
• Urinary tract infections, genital infections
• Increased or more frequent urination
• Common cold, sore throat, upper respiratory tract infection
• Diarrhea, flatulence

Serious side effects, though rare, can include lactic acidosis (with symptoms like weakness, difficulty breathing, or stomach pain) and ketoacidosis (nausea, vomiting, confusion, fruity breath). Allergic reactions and pancreatitis are also possible serious side effects.

Precautions

• Allergies: Do not take if you are allergic to dapagliflozin, sitagliptin, metformin, or any other components.
• Medical Conditions: Not recommended for patients with severe liver or kidney disease, Type 1 diabetes, metabolic acidosis, or diabetic ketoacidosis.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding. It is generally not recommended during pregnancy or breastfeeding.
• Alcohol: Avoid excessive alcohol intake as it increases the risk of hypoglycemia and lactic acidosis.
• Interactions: Inform your doctor about all other medications, including herbal supplements, as interactions can occur with insulin, sulfonylureas, diuretics, certain heart medicines, and gastric medicines.
• Hydration: Drink plenty of fluids to prevent dehydration.

Storage

Store in a cool and dry place, away from direct sunlight, and out of the sight and reach of children. The recommended storage temperature is below 30ºC.

What is SGLTD TRIO 500 Tablet used for?

SGLTD TRIO 500 Tablet is used for the management of Type 2 Diabetes Mellitus in adults, especially when blood sugar levels are not adequately controlled by metformin alone or dual therapy. It helps improve blood sugar control, supports weight loss, and can reduce the risk of heart failure and diabetic kidney disease.

How does SGLTD TRIO 500 Tablet work?

This medicine is a combination of three antidiabetic agents: Dapagliflozin, Sitagliptin, and Metformin. Dapagliflozin (an SGLT2 inhibitor) removes excess sugar from the body via urine. Sitagliptin (a DPP-4 inhibitor) increases the amounts of natural substances that lower blood sugar when it's high by boosting insulin release and decreasing glucagon levels. Metformin (a biguanide) reduces sugar production by the liver and delays sugar absorption from the intestines, also improving the body's sensitivity to insulin.

What is the usual dosage for SGLTD TRIO 500 Tablet?

SGLTD TRIO 500 Tablet should be taken exactly as advised by your doctor. It can be taken with or without food, but it is recommended to take it consistently at the same time each day for optimal benefits. Do not crush, break, or chew the tablet.

What are the possible side effects of SGLTD TRIO 500 Tablet?

Common side effects include urinary tract infections, nasal congestion, sore throat, upper respiratory tract infections, vomiting, nausea, abdominal pain, headache, and stomach upset. Some individuals might also experience fungal infections in the genital area. More serious but rare side effects can include lactic acidosis, ketoacidosis, pancreatitis, and allergic reactions.

Is SGLTD TRIO 500 Tablet safe during pregnancy or breastfeeding?

SGLTD TRIO 500 Tablet is generally not recommended during pregnancy due to limited information on its effects and should be used only if the potential benefits outweigh the potential risks to the fetus. It is also generally not recommended while breastfeeding as metformin, one of its components, is present in human milk. Always consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Can SGLTD TRIO 500 Tablet be taken with other medications?

Inform your doctor about all other medicines, herbal remedies, or supplements you are taking, as SGLTD TRIO 500 Tablet can interact with various drugs. Particular caution is needed if you are taking diuretics (water pills), insulin, sulfonylureas, certain antifungals (e.g., ketoconazole), antibacterials (e.g., clarithromycin), or HIV/AIDS medications (e.g., ritonavir), as these can increase the risk of side effects like dehydration or hypoglycemia.

What precautions should be taken while taking SGLTD TRIO 500 Tablet?

Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia and lactic acidosis. This medicine is not recommended for people with Type 1 diabetes, severe kidney or liver disease, metabolic acidosis, or diabetic ketoacidosis. Regular monitoring of blood sugar levels and kidney function is crucial. Also, ensure adequate fluid intake to prevent dehydration.

What happens if a dose of SGLTD TRIO 500 Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should SGLTD TRIO 500 Tablet be stored?

SGLTD TRIO 500 Tablet should be stored in a cool and dry place, away from direct sunlight, typically at 10ºC to 25ºC or below 30ºC. Keep it out of the sight and reach of children.