Lizomed-xl Dry Syp

LIZOMED-XL DRY SYP by AGLOWMED LTD.

Name

• Brand Name: LIZOMED-XL DRY SYP, Lizomed Dry Syrup, Lizomed-XL Paediatric Dry Syrup
• Manufacturer: AGLOWMED LTD.

Composition

• Active Ingredient: Linezolid (100mg/5ml or 100mg)

Uses LIZOMED-XL DRY SYP is an antibiotic belonging to the oxazolidinone class, primarily used to treat various bacterial infections. It is effective against Gram-positive bacteria and resistant strains such as vancomycin-resistant Enterococcus faecium infections.

• Specific conditions include:
  • Bacterial infections of the skin and lungs (pneumonia)
  • Nosocomial pneumonia and community-acquired pneumonia
  • Complicated skin and skin structure infections
  • Diabetic foot infections
  • Intra-abdominal infections
  • Urinary tract infections
  • Resistant tubercular infections
  • It is not effective against viral infections like the common cold or flu.

Dosage and Administration LIZOMED-XL DRY SYP is typically taken orally. The dosage and duration of treatment depend on the medical condition, patient's age, weight, and response to treatment. It can be taken with or without food.

• Reconstitution: For dry syrup, sterile water should be added to the dry powder, and the volume made up to the mark. The reconstituted suspension should be used within 7 days and stored in the refrigerator.
• General Guidance: Always follow the doctor's instructions. Do not crush or chew the medication. Complete the entire course of antibiotics to prevent bacterial resistance.

Side Effects Common side effects are usually temporary and may include:

• Diarrhea, nausea, vomiting, constipation, indigestion, abdominal pain
• Headache, dizziness, insomnia
• Metallic taste, thrush (a fungal infection)
• Anemia, leucopenia, thrombocytopenia (low blood cell counts)

Serious side effects, though less common, can include:

• Serotonin syndrome (especially with certain antidepressants)
• Bone marrow suppression (myelosuppression)
• Visual impairment, including changes in acuity, color vision, or blurred vision, and peripheral or optic neuropathy
• Lactic acidosis
• Increased liver enzymes, hypoglycemia

Precautions

• Interactions: Inform your doctor about all medications, especially antidepressants (MAOIs, SSRIs, TCAs, SNRIs, bupropion, etc.), dopamine, dobutamine, epinephrine, norepinephrine, pseudoephedrine, rifampicin, phenytoin, insulin, or oral antidiabetics, and tramadol, due to potential interactions and increased risks like serotonin syndrome, myelosuppression, hypoglycemia, or seizures.
• Medical Conditions: Use with caution in patients with uncontrolled hypertension, pheochromocytoma, thyrotoxicosis, a history of seizures, diabetes, phenylketonuria, pre-existing myelosuppression, and severe renal or liver impairment.
• Pregnancy and Breastfeeding: Use with caution during pregnancy (moderate effect) and it is generally not recommended during breastfeeding as Linezolid passes into breastmilk.
• Alcohol: Avoid alcohol consumption as it may increase dizziness.
• Driving/Operating Machinery: May cause dizziness and vision problems; exercise caution.
• Monitoring: Regular blood tests (CBC) and visual function monitoring may be required, especially during extended therapy.

Storage Store at room temperature below 25°C, away from direct sunlight and moisture. The reconstituted suspension should be stored in the refrigerator and used within 7 days. Keep out of reach of children.

Here are frequently asked questions about LIZOMED-XL DRY SYP by AGLOWMED LTD., an antibiotic primarily used for pediatric bacterial infections:

What is LIZOMED-XL DRY SYP used for?

LIZOMED-XL DRY SYP is an antibiotic medication primarily used to treat various bacterial infections in children, typically from birth to 11 years of age. It is effective against severe bacterial infections affecting the lungs (such as nosocomial and community-acquired pneumonia), skin and soft tissues, throat, ears, bones, and urinary tract. It is also used for infections resistant to other antibiotics, including vancomycin-resistant Enterococcus faecium infections and resistant tubercular infections. This medicine is not effective against viral infections like the common cold or flu.

How does LIZOMED-XL DRY SYP work?

LIZOMED-XL DRY SYP contains Linezolid, which belongs to the oxazolidinone class of antibiotics. It works by inhibiting bacterial protein synthesis, a crucial process for bacterial survival and growth. By stopping the bacteria from making essential proteins, it prevents their growth and multiplication, ultimately killing the bacteria and treating the infection.

What is the usual dosage for LIZOMED-XL DRY SYP?

The daily dosage of LIZOMED-XL DRY SYP should be administered as advised by your child's doctor. The dose can vary based on the type and severity of the infection, the child's age, and their response to the medication. It is crucial to follow the prescribed dosage and never exceed it without consulting a doctor. For children, a common dosage mentioned is about 10 mg every 8 hours for 14-28 days, but this is a general guideline and a doctor's specific instructions are paramount.

What are the possible side effects of LIZOMED-XL DRY SYP?

Common side effects your child might experience include diarrhea, vomiting, headache, nausea, metallic taste, constipation, and dizziness. More serious, but rare, side effects can include anemia (low red blood cell count), myelosuppression (reduction in bone marrow's ability to produce blood cells), low white blood cell count, and low platelet count. Peripheral and optic neuropathy (nerve damage causing numbness, pain, or vision changes) can also occur. If any side effects persist, worsen, or if you notice any unusual symptoms, consult your child's doctor immediately.

Is LIZOMED-XL DRY SYP safe during pregnancy or breastfeeding?

LIZOMED-XL DRY SYP is primarily a pediatric product. If the active ingredient, Linezolid, were to be considered for adults, it is generally not recommended for use during pregnancy without consulting a doctor, as it falls under pregnancy category C, meaning potential benefits must outweigh potential risks. It also passes into breastmilk, so breastfeeding mothers should avoid it or consult their doctor.

Can LIZOMED-XL DRY SYP be taken with other medications?

LIZOMED-XL DRY SYP can interact with other medications. It should be used with caution and under medical supervision, especially with:

• Monoamine Oxidase Inhibitors (MAOIs): Combining with MAOIs (e.g., selegiline, phenelzine) can increase the risk of serotonin syndrome. MAOIs should be stopped 14 days before starting LIZOMED-XL DRY SYP.
• Adrenergic and Serotonergic Agents: Medicines like tramadol, sumatriptan, or duloxetine can also increase the risk of serotonin syndrome when taken with LIZOMED-XL DRY SYP.
• Antidepressants: Drugs like citalopram, fluvoxamine, paroxetine, sertraline, and fluoxetine can interact, and specific washout periods may be necessary.
• Glimepiride: LIZOMED-XL DRY SYP may increase the effect of glimepiride, raising the risk of low blood glucose. It's crucial to inform your doctor about all other medications, including over-the-counter drugs, herbal supplements, and vitamins, your child is taking.

What precautions should be taken with LIZOMED-XL DRY SYP?

Several precautions should be observed:

• Allergies: Do not give LIZOMED-XL DRY SYP if your child is allergic to linezolid or any other antibiotics.
• Pre-existing Conditions: Caution is advised for children with a history of seizures, hypertension (high blood pressure), hyperthyroidism, phenylketonuria, liver, or kidney problems.
• Dietary Restrictions: Avoid giving large quantities of tyramine-rich foods (e.g., aged cheese, air-dried meats, soy sauce, certain beers) as they can cause a sudden rise in blood pressure.
• Diarrhea: If severe diarrhea, abdominal pain, or blood in stools occurs, inform the doctor. Prolonged use can lead to serious gastrointestinal infections.
• Blood Cell Count: This medicine can lower white blood cell, red blood cell, and platelet counts, requiring monitoring.

What happens if a dose is missed?

If you forget to give your child a dose of LIZOMED-XL DRY SYP, administer it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed one and continue with the regular dosing schedule. Do not double the dose to make up for a missed one without consulting your doctor.

How should LIZOMED-XL DRY SYP be stored?

Store the dry powder at room temperature below 25°C, away from direct sunlight and moisture. Do not freeze it. Once reconstituted with sterile water, the suspension should be stored in the refrigerator and used within 7 days.