Combinase Aq Nasal Spray

COMBINASE AQ Nasal Spray

COMBINASE AQ Nasal Spray, manufactured by Zydus Healthcare Limited (also referred to as Zydus Cadila), is a combination medicine designed to provide comprehensive relief from symptoms associated with allergic rhinitis.

• Name:

  • Brand Name: COMBINASE AQ Nasal Spray
  • Common Name: Azelastine Hydrochloride and Fluticasone Propionate Nasal Spray

• Composition: Each spray delivers Fluticasone Propionate 50 mcg and Azelastine Hydrochloride 140 mcg. Fluticasone Propionate is a corticosteroid, while Azelastine Hydrochloride is an antihistamine/antiallergic.

• Uses: COMBINASE AQ Nasal Spray is primarily used for the treatment of allergic rhinitis, including seasonal and perennial allergies. It effectively alleviates symptoms such as:

  • Sneezing
  • Runny nose
  • Stuffy nose/Nasal congestion
  • Itchy or watery eyes
  • Nasal itching
  • Postnasal drip

• Dosage and Administration: This medicine is for nasal use only. It should be used as advised by a healthcare professional, typically 1-2 sprays into each nostril twice daily. Before use, gently blow the nose, shake the bottle, and insert the nozzle into one nostril while closing the other. Aim the spray towards the sides of the nostril, away from the nasal septum, and breathe gently while spraying. Do not use more often or for longer than recommended.

• Side Effects:

  • Common: Taste change (bitter taste), nosebleeds, headache, dryness and irritation of the nose and throat, cough, upper respiratory tract infection, nasopharyngitis, stomach discomfort, and voice change.
  • Serious: May increase the risk of infection by weakening the immune system, potential for fungal infection (Candida) if used for prolonged periods, growth retardation in children (with long-term use), impaired wound healing, and eye problems like cataracts or glaucoma with prolonged high doses. Seek medical attention if experiencing severe allergic reactions (rash, itching, swelling of face/tongue/throat, severe dizziness, breathing difficulty).

• Precautions:

  • Inform your doctor about any existing nasal infections, injuries, or ulcers, as the spray may increase the risk of nosebleeds and ulceration.
  • Use with caution if you have liver or eye problems (glaucoma, cataracts) or infections like tuberculosis.
  • Not recommended for children below six years of age.
  • Consult a doctor if pregnant or breastfeeding.
  • May cause sleepiness, blurred vision, or dizziness; avoid driving or operating machinery until you know how the medicine affects you.
  • Avoid contact with sick individuals as it may weaken the immune system.

• Storage: Store at a cool and dry place, below 30°C, away from direct sunlight and moisture. Keep out of reach of children. Do not freeze.

COMBINASE AQ NASAL SPRAY is a combination medication manufactured by Zydus Healthcare Limited (also referred to as Zydus Cadila in some sources) used to treat symptoms associated with allergic rhinitis.

Here are some frequently asked questions about COMBINASE AQ NASAL SPRAY:

What is COMBINASE AQ NASAL SPRAY used for?

COMBINASE AQ NASAL SPRAY is primarily used for the treatment of allergic rhinitis. It helps to relieve symptoms such as sneezing, runny nose, stuffy nose, nasal congestion, and watery or itchy eyes caused by allergies.

How does COMBINASE AQ NASAL SPRAY work?

This nasal spray contains two active ingredients: Fluticasone Propionate and Azelastine. Fluticasone Propionate is a steroid that works by reducing inflammation and irritation in the nasal passages by blocking the release of certain chemical messengers that cause these effects. Azelastine is an antiallergic agent that works by blocking the action of histamine, a substance in the body responsible for causing allergic symptoms like sneezing, runny nose, and watery eyes. Together, they help to reduce swelling and inflammation in the inner lining of the nose.

What is the usual dosage of COMBINASE AQ NASAL SPRAY?

COMBINASE AQ NASAL SPRAY should be used as directed by your doctor. It is typically administered by spraying it inside both nostrils, one by one. Generally, it is recommended to blow your nose gently before use, close one nostril, insert the bottle tip into the other, direct the spray towards the sides of your nostril (away from the cartilage), and sniff hard as you spray. Repeat for the other nostril. Do not use it more often or for longer than recommended, as excessive use can worsen symptoms.

What are the possible side effects of COMBINASE AQ NASAL SPRAY?

Common side effects can include taste changes, headache, nosebleeds, cough, upper respiratory tract infection, dryness in the mouth, nasopharyngitis (inflammation of the throat and nasal passages), stomach discomfort, and voice changes. Most of these side effects are usually temporary and resolve over time. If any side effects persist or worsen, it's important to consult your doctor.

Is COMBINASE AQ NASAL SPRAY safe during pregnancy or breastfeeding?

Limited information is available regarding the safe use of COMBINASE AQ NASAL SPRAY during pregnancy, and animal studies have shown potential harmful effects on the developing baby. Therefore, it is generally advised to avoid its use during pregnancy unless considered essential by your doctor.

For breastfeeding women, the medicines present in COMBINASE AQ NASAL SPRAY are not known to be secreted in breastmilk in significant amounts, suggesting it is probably safe if prescribed by a doctor. However, it is still advised to use it only if prescribed by your doctor.

Can COMBINASE AQ NASAL SPRAY be taken with other medications?

Certain medicines can interact with COMBINASE AQ NASAL SPRAY. It is crucial to inform your doctor about all the medications you are taking, including prescribed, non-prescribed, herbal medicines, and dietary supplements. Special caution is advised if you are taking medicines for brain-related disorders or anti-HIV medicines like ritonavir.

What precautions should be taken?

Inform your doctor if you have recently undergone nasal or paranasal sinus surgery, have an ulcer or wound in your nose, or are suffering from a fungal, bacterial, or viral infection of the airways or throat. Also, tell your doctor if you have high blood pressure, heart disease, eye problems like glaucoma or cataracts, or disorders related to the immune system, kidney, or liver. This spray is generally not recommended for children below 6 or 12 years of age, depending on the source. Avoid alcohol intake as it may worsen some side effects.

What happens if a dose is missed?

If you miss a dose of COMBINASE AQ NASAL SPRAY, use it as soon as you remember. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Do not overuse the medicine to compensate for a missed dose.

How should it be stored?

COMBINASE AQ NASAL SPRAY should be stored in its original container, tightly closed, at room temperature, away from heat and direct light. Do not freeze it, and keep it out of the reach of children and pets.