Brillo 180 Mg Tablet (10 Tab)

BRILLO 180 MG TABLET

BRILLO 180 MG TABLET is a medication primarily used for the management of high cholesterol levels. It is manufactured by SUN PHARMA LABORATORIES LTD.

• Name:

  • Brand Name: BRILLO 180 MG TABLET
  • Generic Name: Bempedoic Acid

• Composition:

  • Active Ingredient: Each tablet contains Bempedoic Acid 180 mg.
  • Class: It belongs to a class of drugs known as Adenosine Triphosphate-Citrate Lyase (ACL) inhibitors.

• Uses:

  • BRILLO 180 MG TABLET is prescribed to lower low-density lipoprotein (LDL) cholesterol levels in adult patients.
  • It is used in individuals with primary hypercholesterolemia (high cholesterol) or mixed dyslipidemia (lipid imbalance).
  • By inhibiting cholesterol production in the liver, it helps reduce the risk of cardiovascular events such as heart attacks and strokes.
  • This medication is typically used in conjunction with a healthy diet, exercise, and sometimes other cholesterol-lowering medicines like statins.

• Dosage and Administration:

  • The typical dosage is usually one tablet once a day.
  • It should be taken orally with water, with or without food.
  • Swallow the tablet whole; do not crush, chew, or break it.
  • For optimal effectiveness, it is recommended to take the medication regularly and at approximately the same time each day.

• Side Effects:

  • Common Side Effects: Muscle pain, back pain, stomach discomfort, anemia, increased liver enzymes, bronchitis, respiratory infections, muscle spasms, and gout.
  • Serious Side Effects (Consult your doctor immediately if experienced): Tendon rupture, joint pain (ankle, knee, or great toe), bloody urine, body aches, chest tightness, chills, cough, cough producing mucus, difficulty urinating, dizziness, ear congestion, fainting, fast or irregular heartbeat, fever, frequent urination, severe headache, joint stiffness or swelling, loss of voice, lower back/side/stomach pain, pale skin, runny or stuffy nose, sneezing, sore throat, swelling of the feet or lower legs, trouble breathing, unusual bleeding or bruising, or unusual tiredness or weakness.

• Precautions:

  • Pregnancy and Breastfeeding: Avoid use during pregnancy and breastfeeding; consult a doctor for advice.
  • Alcohol: It is advisable to limit or avoid alcohol consumption while on this medication.
  • Children: Not recommended for use in children; a pediatrician should be consulted for suitable alternatives.
  • Elderly: Use with caution in elderly patients; medical consultation is advised.
  • Medical Conditions: Inform your doctor if you have kidney disease, liver disease, or a history of tendon disorders. Avoid use if you have a history of tendon disorders or liver disease.
  • Allergies: Do not take if you are allergic to Bempedoic Acid or any other ingredients of the tablet.
  • Drug Interactions: Inform your doctor about all other medications you are currently taking, as some may interact with BRILLO.
  • Food Interactions: Avoid consuming grapefruit or grapefruit juice, as it may interact with the medication.
  • Do not discontinue the medication without consulting your doctor, even if cholesterol levels improve.

• Storage:

  • Store in a cool and dry place, away from direct sunlight and moisture.
  • Keep the tablets out of the reach and sight of children.
  • Store between 10°C to 25°C or below 30°C.

What is BRILLO 180 MG TABLET used for?

BRILLO 180 MG TABLET, containing Bempedoic acid, is primarily used to lower high levels of "bad" cholesterol (LDL-C) in adults. It treats conditions such as primary hypercholesterolemia (high cholesterol) and mixed dyslipidemia (lipid imbalance). It is often prescribed alongside a healthy diet and exercise, and sometimes with other cholesterol-lowering medications like statins, especially for patients with established cardiovascular disease or those at high risk who cannot tolerate statins, to reduce the risk of heart attacks and strokes.

How does BRILLO 180 MG TABLET work?

BRILLO 180 MG TABLET works by inhibiting an enzyme in the liver called adenosine triphosphate-citrate lyase (ACL). This enzyme is crucial for the production of cholesterol in the body. By blocking ACL, Bempedoic acid reduces cholesterol synthesis in the liver and leads to an increase in LDL receptors, which enhances the removal of LDL cholesterol from the bloodstream, thereby lowering overall cholesterol levels.

What is the usual dosage for BRILLO 180 MG TABLET?

The usual recommended dosage for BRILLO 180 MG TABLET is one 180 mg tablet taken once daily. It can be taken with or without food. To achieve the best results, it is recommended to take the tablet at approximately the same time each day, swallowed whole with water.

What are the possible side effects of BRILLO 180 MG TABLET?

Common side effects of BRILLO 180 MG TABLET may include upper respiratory tract infections, muscle spasms, back pain, pain in the extremities (shoulders, legs, arms), abdominal pain or discomfort, anemia, and increased liver enzymes. More serious, though less common, side effects can include an increase in blood uric acid levels (which may lead to gout) and an increased risk of tendon rupture or injury.

Is BRILLO 180 MG TABLET safe during pregnancy or breastfeeding?

BRILLO 180 MG TABLET is generally not recommended during pregnancy or breastfeeding. There is insufficient data to evaluate the risk of major birth defects, miscarriage, or adverse effects on the fetus during pregnancy. For breastfeeding, it is not known whether Bempedoic acid is secreted in human milk, and its mechanism of action (decreasing cholesterol synthesis) could potentially harm a breastfed infant. Patients should consult their doctor before using this medication if pregnant or breastfeeding.

Can BRILLO 180 MG TABLET be taken with other medications?

BRILLO 180 MG TABLET can interact with certain other medications, particularly some statins. Coadministration with simvastatin at doses greater than 20 mg or pravastatin at doses greater than 40 mg is not recommended due to an increased risk of muscle-related side effects. It's important to inform your doctor about all medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.

What precautions should be taken with BRILLO 180 MG TABLET?

Patients should exercise caution if they have a history of gout or hyperuricemia, as BRILLO 180 MG TABLET can increase uric acid levels. Those with a history of tendon problems or kidney/liver disease should also use this medication with caution and inform their doctor, as it may increase the risk of tendon rupture or affect liver function. Regular monitoring of cholesterol and liver function levels may be recommended.

What happens if a dose of BRILLO 180 MG TABLET is missed?

If you miss a dose of BRILLO 180 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should BRILLO 180 MG TABLET be stored?

BRILLO 180 MG TABLET should be stored in a cool and dry place, away from heat, moisture, and direct sunlight. It should be kept at a temperature not exceeding 30°C and out of the reach and sight of children.