Dyrect Tab

DYRECT TAB by OZONE PHARMACEUTICALS LTD.

Name: Dyrect Tablet

Composition: Dyrect Tablet is a fixed-dose combination medication containing:

• Diclofenac (50 mg)
• Serratiopeptidase (10 mg) Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking chemical messengers responsible for pain and swelling. Serratiopeptidase is an enzyme that helps break down abnormal proteins at inflammation sites, promoting healing and reducing swelling by thinning fluids in injured tissues for smoother drainage.

Uses: Dyrect Tablet is primarily used for the short-term relief of pain, inflammation, and swelling. It is prescribed for various conditions, including:

• Rheumatoid Arthritis, Osteoarthritis, and Ankylosing Spondylitis
• Mild to moderate pain, including muscle pain, back pain, toothache, earache, and throat pain
• Dysmenorrhea (menstrual pain)
• Migraine headaches
• Bursitis and Tendinitis
• Gout
• Postoperative inflammation, oedema, and pain, as well as pain due to bone or soft tissue injury.

Dosage and Administration: Take Dyrect Tablet exactly as directed by your doctor. It should be swallowed whole with a glass of water and not crushed or chewed. It can be taken with or without food, but taking it with food or milk products can help reduce gastrointestinal distress. Do not exceed the prescribed dose or duration. Maintaining adequate fluid intake is also recommended.

Side Effects: Common side effects associated with Dyrect Tablet may include:

• Abdominal pain, heartburn, indigestion, stomach pain
• Nausea and vomiting
• Diarrhea or constipation
• Loss of appetite
• Rash
• Dizziness
• Tinnitus (ringing in the ears) Most of these side effects are typically mild and transient. If side effects persist or worsen, consult your doctor.

Precautions:

• Allergies: Do not take if allergic to Diclofenac, Serratiopeptidase, or other NSAIDs like aspirin, especially if it causes severe asthma, rashes, or other allergic reactions.
• Gastrointestinal: Caution is advised if you have a history of stomach ulcers, bleeding in the stomach or intestine, or other gastrointestinal issues. Long-term use may increase the risk of severe bleeding and ulcers.
• Cardiovascular: Use with caution in patients with heart conditions, high blood pressure, or fluid retention, as NSAIDs can exacerbate these conditions and may be associated with a small increased risk of heart attack.
• Hepatic/Renal: Caution is necessary for individuals with liver or kidney problems. Dosage adjustments may be required, and regular monitoring of liver and kidney function may be advised for long-term treatment.
• Pregnancy and Breastfeeding: Dyrect Tablet is generally not recommended during pregnancy, particularly in the first and last trimesters, due to potential harm to the fetus. It is also not recommended for use by breastfeeding mothers as traces may pass into breast milk.
• Alcohol: Avoid alcohol consumption while taking this medication as it can increase the risk of liver damage and gastrointestinal bleeding.
• Driving/Operating Machinery: This medicine may cause dizziness or drowsiness; therefore, exercise caution when driving or operating machinery until you know how it affects you.
• Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are taking, as Dyrect Tablet can interact with certain drugs, including those for heart failure (like Digoxin), Lithium, Methotrexate, and diabetes medications. Avoid within 2 weeks of Mifepristone administration.
• Children: Not recommended for use in children under 10 years of age.

Storage: Store Dyrect Tablet below 30°C, away from moisture and heat. Keep it in its original container, tightly closed, and out of the reach of children and pets. Do not use expired or damaged medicines and dispose of any unused medicine properly.

Dyrect Tablet, manufactured by Ozone Pharmaceuticals Ltd., is a combination medication containing Diclofenac and Serratiopeptidase. It is primarily used for its pain-relieving and anti-inflammatory properties.

Here are some frequently asked questions about Dyrect Tablet:

What is Dyrect Tablet used for?

Dyrect Tablet is used to reduce pain and inflammation in various conditions. These include rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, muscle pain, back pain, toothache, earache, throat pain, migraine headaches, and menstrual pain.

How does Dyrect Tablet work?

Dyrect Tablet contains two active ingredients: Diclofenac and Serratiopeptidase. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of specific chemical messengers in the body, called prostaglandins, which are responsible for causing pain and swelling. Serratiopeptidase is an enzyme that helps break down abnormal proteins at the site of inflammation, reducing swelling and promoting smoother fluid drainage from affected tissues.

What is the usual dosage for Dyrect Tablet?

The dosage of Dyrect Tablet is determined by your doctor based on your individual condition, age, and response to treatment. It is typically taken orally, with or after food, and should be swallowed whole without crushing or chewing. It is crucial to follow your doctor's instructions and not exceed the prescribed dose or duration.

What are the possible side effects of Dyrect Tablet?

Common side effects may include abdominal pain, heartburn, indigestion, nausea, vomiting, diarrhea, and loss of appetite. Less common but more serious side effects can include skin rash, dizziness, drowsiness, and an increased risk of gastrointestinal bleeding or ulcers, especially with prolonged use. Long-term use or high doses may also affect kidney and liver function, and there's a small increased risk of heart attack or stroke. If you experience persistent or severe side effects, contact your doctor.

Is Dyrect Tablet safe during pregnancy or breastfeeding?

Dyrect Tablet is generally not recommended for use during pregnancy, especially in the first and last trimesters, as it may harm the fetus. It should be used with caution, if at all, during breastfeeding, and a doctor's consultation is essential.

Can Dyrect Tablet be taken with other medications?

Dyrect Tablet can interact with various medications. You should avoid taking it with other NSAIDs (like aspirin, ibuprofen, naproxen) as this increases the risk of side effects. It can also interact with blood thinners (like warfarin), medicines for high blood pressure, diabetes medications, digoxin, methotrexate, cyclosporine, lithium, insulin, sulfonylureas, and potassium-sparing diuretics. Always inform your doctor about all other medicines, supplements, or herbal products you are currently taking to prevent potential interactions.

What precautions should be taken while using Dyrect Tablet?

Avoid consuming alcohol while taking Dyrect Tablet, as it can increase the risk of stomach bleeding and other side effects. Use with caution if you have a history of gastrointestinal disorders, heart conditions (like heart failure or high blood pressure), kidney or liver diseases. Dyrect Tablet is not recommended for individuals under 18 years of age. Since it may cause dizziness or drowsiness, avoid driving or operating heavy machinery until you know how the medicine affects you.

What happens if a dose of Dyrect Tablet is missed?

If you miss a dose of Dyrect Tablet, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Dyrect Tablet be stored?

Dyrect Tablet should be stored below 30°C in a cool, dry place, away from moisture and heat. Keep it in its original container, tightly closed, and out of the reach of children and pets.