Deca-durabolin 25mg Inj

DECA-DURABOLIN 25MG INJ by ZYDUS HEALTHCARE LIMITED

Name

Brand Name: DECA-DURABOLIN 25MG INJ Common Name: Nandrolone Decanoate Injection

Composition

Each mL of DECA-DURABOLIN 25MG INJ contains 25 mg of the active ingredient Nandrolone Decanoate. It also includes benzyl alcohol and arachis (peanut) oil as inactive ingredients.

Uses

DECA-DURABOLIN 25MG INJ is an anabolic steroid prescribed for various conditions. It is primarily used to treat osteoporosis in postmenopausal women by strengthening bones and reducing fracture risk. It is also indicated for certain types of anemia, including those related to chronic kidney failure, by stimulating red blood cell production. Additionally, it can be used for muscle wasting and severe weight loss due to chronic illness, advanced breast cancer in women as part of supportive care, and in patients on long-term corticosteroid therapy.

Dosage and Administration

This medicine is administered as a deep intramuscular injection into the muscle (e.g., buttock, upper leg, or upper arm) by a healthcare professional. Self-administration is not recommended. The dosage and frequency vary based on the specific condition and individual response, typically ranging from 50 to 200 mg every 2 to 4 weeks for adults, or specifically 50 mg once every 3 weeks for postmenopausal osteoporosis. Use in children is generally not recommended due to potential effects on growth and development.

Side Effects

Common side effects include pain or reaction at the injection site, fluid retention (edema, swelling of ankles or feet), nausea, acne, itching, and changes in sexual desire. More serious side effects can involve impaired liver function, abnormal blood fat levels, increased blood pressure, and virilization in women (e.g., hoarseness or voice changes, increased body/facial hair, irregular periods). Long-term use has been associated with rare reports of hepatocellular neoplasms and peliosis hepatitis.

Precautions

DECA-DURABOLIN 25MG INJ is contraindicated during pregnancy and lactation. It should not be used in males with known or suspected prostatic or mammary carcinoma, or in individuals hypersensitive to nandrolone decanoate or arachis oil (peanut allergy). Caution is advised in patients with cardiac failure, liver disease, kidney problems, diabetes, high blood pressure, or benign prostatic hypertrophy. It contains benzyl alcohol and is not for use in children younger than 3 years. Close monitoring of liver function, cholesterol levels, and cardiovascular health is recommended during treatment. This medicine may interact with anticoagulants (e.g., warfarin) and antidiabetics, and can interfere with certain lab tests. Misuse to enhance athletic performance carries serious health risks.

Storage

Store DECA-DURABOLIN 25MG INJ in its original packaging in a cool, dark place, below 30°C. Do not refrigerate as this can make the injection difficult to administer. Keep out of the reach and sight of children.

DECA-DURABOLIN 25MG INJ by ZYDUS HEALTHCARE LIMITED contains Nandrolone Decanoate, an anabolic steroid.

What is DECA-DURABOLIN 25MG INJ used for?

DECA-DURABOLIN 25MG INJ is primarily used to treat osteoporosis in postmenopausal women, helping to strengthen bones and reduce fracture risk. It is also used in certain types of anemia, such as anemia due to chronic kidney disease or aplastic anemia, by stimulating red blood cell production. Additionally, it may be used as supportive care in advanced breast cancer in women and for patients on long-term corticosteroid therapy.

How does DECA-DURABOLIN 25MG INJ work?

This medicine contains nandrolone decanoate, which is a synthetic anabolic steroid related to the male hormone testosterone. It works by promoting protein synthesis, which aids in muscle repair and growth, and helps in retaining nitrogen in the body to build lean muscle mass. It also positively influences calcium metabolism to increase bone mass and stimulates the bone marrow to produce red blood cells. Nandrolone decanoate has enhanced anabolic effects and reduced androgenic effects compared to testosterone.

What is the usual dosage for DECA-DURABOLIN 25MG INJ?

DECA-DURABOLIN 25MG INJ is administered via deep intramuscular injection and should only be given by a doctor or trained nurse. The dosage varies based on the condition being treated. For postmenopausal osteoporosis, a common dose is 50 mg every three weeks (though the user specified 25mg, implying a different frequency or lower dose might be prescribed for a 25mg product). For anemia due to chronic kidney failure, women might receive 100 mg once a week, and men 200 mg once a week. For aplastic anemia, the recommended dose is 50–100 mg once a week. Your doctor will determine the appropriate dose and frequency for your specific condition.

What are the possible side effects of DECA-DURABOLIN 25MG INJ?

Common side effects can include acne, swelling (edema) in the feet, ankles, and legs, nausea, vomiting, and breast enlargement. In women, side effects may include signs of masculinization (virilization) such as a hoarse voice, increased facial and body hair (hirsutism), male pattern baldness, enlarged clitoris, and irregular or absent menstrual cycles. In men, possible side effects include decreased testes size and function, low sperm count, painful erections, and breast enlargement. More serious, though rare, side effects can include liver problems, such as liver tumors or blood-filled cysts (peliosis hepatis), and cardiovascular issues like high blood pressure.

Is DECA-DURABOLIN 25MG INJ safe during pregnancy or breastfeeding?

No, DECA-DURABOLIN 25MG INJ is considered unsafe during pregnancy as it can severely harm the fetus due to the risk of fetal virilization. It is also not recommended for use by breastfeeding mothers as it may affect the baby, and manufacturers generally advise against its use during lactation. Women should avoid conceiving during treatment.

Can DECA-DURABOLIN 25MG INJ be taken with other medications?

Yes, but caution is advised, and your doctor should be informed about all medications you are taking. DECA-DURABOLIN can enhance the effects of anticoagulant medications (like coumarin derivatives), potentially requiring dosage adjustments. It can also improve glucose tolerance, which might necessitate a reduction in doses of insulin or oral antidiabetic medications. Concomitant use with corticosteroids may increase the risk of water retention.

What precautions should be taken?

Patients with heart failure, kidney dysfunction, hypertension, migraines, or diabetes mellitus require close monitoring. Those with cancer metastasizing to the bones should also be carefully monitored due to the risk of hypercalcemia. The injection contains peanut oil and benzyl alcohol, so it is contraindicated in patients with allergies to peanuts or soy, and in premature infants or neonates due to potential toxicity from benzyl alcohol. The recommended dosages should not be exceeded, and treatment may be discontinued if signs of virilization occur.

What happens if a dose is missed?

If you miss an injection, contact your doctor or nurse immediately to reschedule it. It is important to maintain the prescribed schedule for optimal effectiveness.

How should it be stored?

While specific storage instructions for "DECA-DURABOLIN 25MG INJ by ZYDUS HEALTHCARE LIMITED" were not explicitly found, anabolic steroid injections typically require storage at room temperature, protected from light and moisture. Always follow the storage instructions provided on the packaging or by your healthcare professional.