Glz Xr 60 Mg Tablet (15 Tab)

GLZ XR 60 MG TABLET (15 TAB) by ALEMBIC PHARMACEUTICALS LIMITED

GLZ XR 60 MG TABLET is an antidiabetic medication manufactured by Alembic Pharmaceuticals Ltd., primarily used in the management of Type 2 Diabetes Mellitus.

• Name:

  • Brand Name: GLZ XR 60 MG TABLET
  • Common Name: Gliclazide Extended Release

• Composition:

  • Each tablet contains Gliclazide 60 mg. Gliclazide belongs to the class of sulfonylurea antidiabetic agents.

• Uses: GLZ XR 60 MG TABLET is prescribed for adults with Type 2 Diabetes Mellitus when diet, exercise, and lifestyle modifications alone are insufficient to achieve adequate blood sugar control. It works by stimulating the pancreas to secrete more insulin and by increasing the body's sensitivity to insulin, thereby lowering blood glucose levels.

• Dosage and Administration:

  • Typically taken once daily, preferably with breakfast or the first main meal of the day.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • The exact dose and duration of therapy will be determined by a physician based on the patient's age, body weight, and medical condition. Initial adult doses may range from 40-80 mg daily and can be adjusted up to 320 mg daily. Doses exceeding 160 mg daily are generally administered in two divided doses.

• Side Effects:

  • Common: Hypoglycemia (low blood sugar, symptoms include increased hunger, sweating, shakiness, weakness, irregular heartbeat, dizziness), headache, nausea, vomiting, stomach pain, indigestion, diarrhea, constipation, and weight gain.
  • Serious: Severe allergic reactions (e.g., skin rash, swelling of the face, tongue, or throat causing difficulty breathing), signs of liver problems (e.g., fever, yellowing of skin/eyes, fatigue), seizures, chest pain, or severe skin reactions (peeling, blistering). Immediate medical attention is required if these occur.

• Precautions:

  • Contraindicated in patients with Type 1 diabetes mellitus, diabetic ketoacidosis, severe liver or kidney disease, or known allergy to Gliclazide or other sulfonylureas.
  • Not recommended for use during pregnancy or breastfeeding.
  • Caution should be exercised in patients with liver or kidney problems, hormonal disorders, G6PD deficiency, or those who are malnourished.
  • Alcohol consumption should be avoided as it can increase the risk of hypoglycemia.
  • Patients should carry a sugary snack to counteract unexpected low blood sugar levels, which can impair driving ability or the operation of machinery.
  • Inform your doctor about all other medications, supplements, or herbal products being taken to avoid potential drug interactions (e.g., with other antidiabetics, antifungals, antibiotics, ACE inhibitors, corticosteroids).
  • Do not discontinue the medicine without consulting your doctor. Not recommended for children.

• Storage:

  • Store in a cool, dry place, protected from light, at room temperature (below 25°C or 30°C).
  • Keep out of the sight and reach of children and pets.

GLZ XR 60 mg Tablet contains Gliclazide, a medication used to manage type 2 diabetes mellitus in adults. It is an extended-release formulation, meaning the medicine is released slowly over time.

Here are some frequently asked questions about GLZ XR 60 mg Tablet:

What is GLZ XR 60 mg Tablet used for?

GLZ XR 60 mg Tablet is primarily used to control high blood sugar levels in adults with type 2 diabetes mellitus when diet, exercise, and weight loss alone are insufficient. By managing blood sugar, it helps reduce the risk of serious diabetes complications such as kidney damage, nerve damage, blindness, and heart problems.

How does GLZ XR 60 mg Tablet work?

This medicine belongs to a class of drugs called sulfonylureas. Gliclazide works mainly by stimulating the beta cells in the pancreas to produce and release more insulin. It also helps the body's cells to use insulin more effectively, thereby lowering blood sugar levels. The extended-release (XR) formulation ensures a gradual and consistent delivery of the medication throughout the day.

What is the usual dosage for GLZ XR 60 mg Tablet?

The typical starting dose for Gliclazide XR is 30 mg once daily, which may be adjusted by your doctor based on your blood sugar levels. For GLZ XR 60 mg, the usual dose is one tablet (60 mg) once daily, taken with breakfast. The maximum daily dose for slow-release gliclazide is 120 mg. Always follow your doctor's instructions for dosage and administration.

What are the possible side effects of GLZ XR 60 mg Tablet?

The most common side effect is hypoglycemia (low blood sugar), which can cause symptoms like dizziness, sweating, shaking, headache, confusion, and a fast heartbeat. Other possible side effects include stomach upset, nausea, vomiting, diarrhea, constipation, and skin rash. If you experience severe or persistent side effects, or signs of very low blood sugar, seek medical attention.

Is GLZ XR 60 mg Tablet safe during pregnancy or breastfeeding?

GLZ XR 60 mg Tablet is generally not recommended during pregnancy or breastfeeding. For pregnant women with diabetes, insulin is typically the preferred treatment to maintain blood glucose levels. If you are pregnant, planning a pregnancy, or breastfeeding, inform your doctor so they can advise on a more suitable treatment.

Can GLZ XR 60 mg Tablet be taken with other medications?

Gliclazide can interact with various medications, potentially increasing or decreasing its effect on blood sugar. For example, some antibiotics (like miconazole, fluconazole, ciprofloxacin), certain blood thinners (like warfarin), beta-blockers, and other diabetes medications can increase the risk of low blood sugar. Conversely, drugs like corticosteroids, danazol, and some diuretics might reduce its blood sugar-lowering effect. Always inform your doctor or pharmacist about all other medicines, supplements, or herbal remedies you are taking.

What precautions should be taken while taking GLZ XR 60 mg Tablet?

You should consistently follow your prescribed diet and exercise plan. Monitor your blood sugar levels regularly as advised by your doctor. Be cautious of hypoglycemia symptoms, especially if you skip meals, exercise strenuously, or consume alcohol. This medication is not suitable for type 1 diabetes or for individuals with severe kidney or liver problems. Inform your doctor if you have a G6PD deficiency, as sulfonylureas can cause hemolytic anemia in such cases.

What happens if a dose of GLZ XR 60 mg Tablet is missed?

If you miss a dose of GLZ XR 60 mg Tablet, skip the missed dose and take your next dose at the regularly scheduled time. Do not take a double dose to make up for a forgotten one. If you frequently miss doses, consider setting an alarm or consulting your pharmacist for strategies to help you remember.

How should GLZ XR 60 mg Tablet be stored?

Store GLZ XR 60 mg Tablet in a cool, dry place, away from direct sunlight and moisture, and at room temperature (between 15°C and 30°C). Keep the medicine in its original packaging and out of reach of children and pets. Do not use expired tablets.