Angispan Tr 2.5 Mg Capsules

ANGISPAN TR 2.5 MG CAPSULES

Angispan TR 2.5 MG Capsules, manufactured by USV LTD, are an anti-anginal medication used to manage and prevent various heart-related conditions.

Name

• Brand Name: ANGISPAN TR 2.5 MG CAPSULES
• Common Name: Glyceryl Trinitrate (also known as Nitroglycerin)

Composition

• Active Ingredient: Glyceryl Trinitrate 2.5 mg (Nitroglycerin)

Uses

ANGISPAN TR 2.5 MG CAPSULES are primarily used for the following conditions:

• Angina Pectoris (Chest Pain): It is prescribed to prevent and treat chest pain or discomfort caused by reduced blood flow and insufficient oxygen to the heart muscle, often due to coronary artery disease.
• Heart Failure: It helps in managing heart failure.
• Hypertension during Surgeries: Can be used to lower blood pressure during surgical procedures.
• Chronic Anal Fissures: Also indicated for chronic anal fissures.

Dosage and Administration

• ANGISPAN TR 2.5 MG CAPSULES should be taken orally as prescribed by your doctor.
• Swallow the capsule whole with water; do not chew, crush, or break it.
• It can be taken with or without food, but it is recommended to take it at the same time every day to maintain consistency and avoid missed doses.
• Do not exceed the recommended dose, as this can lead to harmful effects and potential tolerance, making the medicine less effective over time.
• Do not stop taking this medicine abruptly, as it may cause a sudden return of angina symptoms. Your doctor will gradually reduce the dose before stopping it completely.

Side Effects

Common side effects include:

• Headache (often throbbing and can be severe)
• Dizziness
• Drowsiness
• Spinning sensation (lightheadedness)
• Lack of energy/fatigue
• Blurred vision
• Flushing of the face
• Nausea and vomiting
• Increased heart rate
• Low blood pressure, especially when standing up (orthostatic hypotension)

Serious side effects that require immediate medical attention:

• Worsening of angina symptoms or chest pain
• Signs of hypoxaemia (low oxygen levels) such as difficulty breathing, increased breathing rate
• Signs of methemoglobinemia (breathing problems, tiredness, bluish discoloration of lips, fingers, or toes)
• Rapid or slowed heartbeat
• Blindness in one eye
• Cerebral ischaemia (impaired blood flow to the brain, causing weakness in limbs)
• Allergic skin reactions (rashes, itching, scaling)

Precautions

• Allergy: Do not take if allergic to glyceryl trinitrate, nitroglycerin, or any components of the capsule.
• Alcohol: Avoid alcohol consumption during treatment, as it can worsen side effects like dizziness, drowsiness, and low blood pressure.
• Driving and Operating Machinery: This medicine can cause drowsiness, dizziness, and blurred vision; therefore, avoid driving or operating heavy machinery.
• Medical Conditions: Inform your doctor if you have or have had:
  • Anaemia
  • Glaucoma (increased pressure in the eye)
  • Increased intracranial pressure (pressure inside the skull)
  • Severely low blood pressure or low blood volume
  • Liver or kidney diseases
  • Underactive thyroid gland
  • Malnutrition or abnormally low oxygen levels in the blood
  • Diseases affecting blood vessels supplying the brain (cerebrovascular diseases)
  • Hypertrophic obstructive cardiomyopathy or other heart conditions
• Drug Interactions:
  • Do not use with medicines for erectile dysfunction (e.g., sildenafil, tadalafil, vardenafil), as this can cause a severe drop in blood pressure.
  • Inform your doctor about all other medications, herbal supplements, and vitamins you are taking, as interactions can occur with drugs like amitriptyline, amlodipine, dihydroergotamine, heparin, prilocaine, antipsychotics, aspirin, and NSAIDs.
• Pregnancy and Breastfeeding: Consult your doctor before using if you are pregnant, planning to become pregnant, or are breastfeeding. It is generally considered safe if prescribed.
• Children and Elderly: Not recommended for use in children. Use with caution in elderly patients.

Storage

• Store in a cool, dark, and dry place, away from direct sunlight and moisture.
• Keep the medicine in its original pack or container and out of sight and reach of children.

What is ANGISPAN TR 2.5 MG CAPSULES used for?

ANGISPAN TR 2.5 MG CAPSULES is primarily used to prevent and manage chest pain, also known as angina pectoris, which occurs when the heart muscle doesn't receive enough oxygen-rich blood. It is prescribed for patients with coronary artery disease and helps alleviate symptoms like chest pressure, squeezing, heaviness, tightness, or pain. It can also be used to manage heart failure and hypertension during surgeries in some cases.

How does ANGISPAN TR 2.5 MG CAPSULES work?

This medicine contains Glyceryl Trinitrate (Nitroglycerin), which belongs to a class of drugs called nitrates. It works by relaxing the smooth muscles within the blood vessels, leading to their widening (vasodilation). This action improves blood supply and oxygen flow to the heart muscles, reducing the heart's workload and thereby relieving chest pain associated with angina.

What is the usual dosage for ANGISPAN TR 2.5 MG CAPSULES?

The dosage of ANGISPAN TR 2.5 MG CAPSULES is determined by your doctor based on your medical condition and response to treatment. It is typically taken orally, with or without food, preferably at a fixed time each day. It's crucial to swallow the capsule whole and not to chew, crush, or break it, as this can release all the medication at once and increase the risk of side effects. Do not consume more than the recommended dose.

What are the possible side effects of ANGISPAN TR 2.5 MG CAPSULES?

Common side effects include throbbing headache, dizziness, spinning sensation, drowsiness, and lack of energy. Headaches are a common indicator that the drug is working. More serious, though rare, side effects can include worsening angina, signs of low oxygen levels (hypoxemia), breathing problems, bluish discoloration of lips or fingers (cyanosis), rapid or slowed heartbeat, and cerebral ischemia. If these symptoms worsen or persist, or if you experience severe side effects, consult your doctor immediately.

Is ANGISPAN TR 2.5 MG CAPSULES safe during pregnancy or breastfeeding?

ANGISPAN TR 2.5 MG CAPSULES should be used with caution during pregnancy and breastfeeding. It is generally considered safe if prescribed by a doctor, but the safety for breastfed infants is not fully known. Always consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding, to weigh the potential benefits against the risks.

Can ANGISPAN TR 2.5 MG CAPSULES be taken with other medications?

ANGISPAN TR 2.5 MG CAPSULES can interact with certain medications. It is crucial to inform your doctor about all medicines, supplements, and herbal products you are currently taking. Particular caution is advised with:

• Erectile dysfunction medications (e.g., sildenafil, tadalafil, vardenafil) as this combination can cause a severe drop in blood pressure.
• Calcium channel blockers (e.g., verapamil, diltiazem) and Beta-blockers (e.g., metoprolol, atenolol).
• Heparin.
• Some other medications for high blood pressure or heart failure.

What precautions should be taken while using ANGISPAN TR 2.5 MG CAPSULES?

Several precautions should be taken:

• Medical Conditions: Inform your doctor if you have conditions such as hypertrophic obstructive cardiomyopathy, anemia, glaucoma (increased eye pressure), raised pressure in the head, underactive thyroid, liver or kidney diseases, very low blood pressure, low blood volume, or diseases affecting brain blood vessels.
• Alcohol: Avoid consuming alcohol, as it can increase dizziness, drowsiness, and the risk of low blood pressure.
• Driving and Machinery: Be cautious when operating machinery or driving, as the medicine can cause dizziness, drowsiness, or blurred vision.
• Sudden Cessation: Do not stop taking the medicine abruptly, as it can worsen angina symptoms. Your doctor will advise on gradual tapering if discontinuation is needed.
• Tolerance: You may develop tolerance over time, making the same dose less effective. Adhere strictly to your prescribed dosing schedule to prevent this.

What happens if a dose of ANGISPAN TR 2.5 MG CAPSULES is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should ANGISPAN TR 2.5 MG CAPSULES be stored?

Store ANGISPAN TR 2.5 MG CAPSULES in a cool, dry place, away from direct sunlight and moisture, and keep it in its original packaging. It should be stored at room temperature, typically between 15-30°C (59-86°F). Keep all medications out of sight and reach of children and pets.