Bempesta 180 Mg Tablet (10 Tab)

BEMPESTA 180 MG TABLET

BEMPESTA 180 MG TABLET, manufactured by Torrent Pharmaceuticals Ltd., is a lipid-lowering medication prescribed to help manage cholesterol levels and reduce the risk of cardiovascular events.

• Composition:

  • Active Ingredient: Bempedoic Acid 180 mg.

• Uses: BEMPESTA 180 MG TABLET is primarily used to lower levels of "bad" cholesterol (Low-Density Lipoprotein or LDL cholesterol) in adults. It is prescribed for:

  • Primary hypercholesterolemia, including heterozygous familial hypercholesterolemia.
  • Mixed dyslipidemia.
  • Reducing the risk of heart disease, heart attack (myocardial infarction), and the need for coronary revascularization procedures in adults who are unable to take recommended statin therapy or require additional LDL-C lowering.
  • It can be used as a standalone therapy or in combination with other cholesterol-lowering medications, most commonly statins, along with diet and lifestyle modifications.

• Dosage and Administration:

  • The typical dosage is one tablet taken once daily.
  • BEMPESTA can be taken with or without food.
  • Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
  • For optimal effectiveness, aim to take the medication at the same time each day to maintain a consistent level in your system.

• Side Effects:

  • Common Side Effects: Upper respiratory tract infection, muscle spasms, increased uric acid levels in the blood (hyperuricemia), back pain, pain in extremities (e.g., shoulder, legs, arms), abdominal pain, stomach pain, anemia, elevated liver enzyme levels, and bronchitis.
  • Gout can occur due to increased uric acid levels.
  • Tendon problems, such as pain, swelling, tears, or inflammation, have also been noted.

• Precautions:

  • Inform your doctor about any pre-existing liver or kidney conditions, a history of gout, or tendon problems before starting this medication.
  • BEMPESTA is generally not recommended for use during pregnancy or while breastfeeding due to potential harm to the unborn baby or infant.
  • Its safety and effectiveness have not been established in children under 18 years of age.
  • Regular monitoring of cholesterol levels, liver function, and kidney function may be necessary during treatment.
  • Do not discontinue the medication without consulting your doctor, as this could lead to a resurgence in cholesterol levels and increased risk of heart-related complications.
  • Caution is advised if you experience dizziness, particularly when driving or operating heavy machinery.
  • Adopting a heart-healthy diet, regular exercise, quitting smoking, and moderating alcohol consumption are crucial alongside medication for comprehensive cholesterol management.

• Storage:

  • Keep BEMPESTA 180 MG TABLET in its original container.
  • Store at room temperature, ideally between 15°C and 30°C.
  • Protect from excessive light and moisture.
  • Keep out of reach of children.
  • Ensure to use the medicine before the expiry date printed on the pack.

Here are some frequently asked questions and answers about BEMPESTA 180 MG TABLET.

What is BEMPESTA 180 MG TABLET used for?

BEMPESTA 180 MG TABLET, containing Bempedoic Acid, is primarily used to lower high levels of "bad" cholesterol (LDL-C) in the blood. It treats conditions like primary hypercholesterolaemia and mixed dyslipidaemia. It can be used alone or in conjunction with statins and other cholesterol-lowering medications, particularly in adults who cannot tolerate statins or require additional cholesterol reduction. The medication also helps reduce the risk of heart disease, heart attack, and the need for coronary revascularization procedures.

How does BEMPESTA 180 MG TABLET work?

BEMPESTA 180 MG TABLET works by inhibiting an enzyme called Adenosine Triphosphate-Citrate Lyase (ACL) in the liver. This enzyme is crucial for the production of cholesterol. By blocking ACL, Bempedoic Acid reduces the liver's ability to synthesize LDL (bad) cholesterol and enhances its removal from the bloodstream, thereby lowering overall cholesterol levels.

What is the usual dosage for BEMPESTA 180 MG TABLET?

The recommended dosage for BEMPESTA 180 MG TABLET is one 180 mg tablet taken once daily. It can be taken with or without food, but it is often advised to take it at the same time each day to maintain consistent levels in your system and maximize effectiveness.

What are the possible side effects of BEMPESTA 180 MG TABLET?

Common side effects may include upper respiratory tract infections, muscle spasms, increased uric acid levels in the blood (hyperuricemia, which can lead to gout), back pain, abdominal pain, bronchitis, pain in extremities (arms, legs, shoulders), anemia (low red blood cell count), and elevated liver enzymes. Most side effects are temporary; however, if they persist or worsen, consult your doctor.

Is BEMPESTA 180 MG TABLET safe during pregnancy or breastfeeding?

BEMPESTA 180 MG TABLET is generally not recommended during pregnancy as it may cause harm to the unborn baby. It is also considered probably unsafe during breastfeeding, as it is unknown if the active ingredient, Bempedoic Acid, passes into breast milk and could potentially harm the infant. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can BEMPESTA 180 MG TABLET be taken with other medications?

Yes, BEMPESTA 180 MG TABLET can be taken with other cholesterol-lowering medications like statins. However, caution is advised as combining it with certain statins (e.g., rosuvastatin, atorvastatin, simvastatin) can increase the risk of muscle spasms. If co-administered with simvastatin, the simvastatin dose should be limited. It may also interact with uric acid-lowering medicines (like allopurinol or febuxostat) by potentially elevating uric acid levels and reducing their effectiveness. Inform your doctor about all other medications you are taking, including those for pulmonary artery hypertension or hepatitis C.

What precautions should be taken while taking BEMPESTA 180 MG TABLET?

Before taking BEMPESTA 180 MG TABLET, inform your doctor if you have severe liver or kidney problems, a history of gout, or any tendon problems. Your doctor may monitor your liver function with blood tests before and during treatment. Be vigilant for signs of gout (tender, reddened, or swollen joints) or tendon issues (pain, swelling, inflammation, or rupture). This medication is not recommended for children under 18 years of age. For elderly patients (75 years and above), it should be used with caution. It is crucial to combine this medication with a heart-healthy lifestyle, including a balanced diet, regular exercise, and avoiding smoking and excessive alcohol. Do not discontinue the medication without consulting your doctor.

What happens if a dose of BEMPESTA 180 MG TABLET is missed?

If you miss a dose of BEMPESTA 180 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should BEMPESTA 180 MG TABLET be stored?

BEMPESTA 180 MG TABLET should be stored in its original container in a cool and dry place, ideally at room temperature (between 15°C and 30°C). Protect it from excessive light and moisture, and keep it out of reach of children. Ensure it is used before the expiry date printed on the pack.