Sitazit D 5/50 Mg (10 Tab)

SITAZIT D 5/50 MG (10 TAB) by GLENMARK LABORATORIES

SITAZIT D 5/50 MG is a combination medication manufactured by Glenmark Laboratories, primarily used in the management of Type 2 Diabetes Mellitus in adults. It helps to effectively control blood sugar levels when diet, exercise, and other medications alone are insufficient.

Composition

SITAZIT D 5/50 MG contains two active ingredients:

• Dapagliflozin: 5 mg
• Sitagliptin: 50 mg (as Sitagliptin Phosphate)

Dapagliflozin works by blocking a protein in the kidneys (SGLT-2), leading to increased excretion of glucose through urine, thus lowering blood sugar levels. Sitagliptin, a DPP-4 inhibitor, increases insulin levels and decreases glucagon levels, thereby reducing the amount of glucose produced by the liver.

Uses

SITAZIT D 5/50 MG is prescribed for:

• Management of Type 2 Diabetes Mellitus in adults.
• Lowering elevated blood glucose levels.
• Improving insulin sensitivity and utilization.
• Reducing the risk of diabetes-related complications such as kidney damage, nerve issues, and cardiovascular events.
• Treatment of chronic kidney disease in adults with reduced kidney function.

Dosage and Administration

The typical dosage of SITAZIT D 5/50 MG is one tablet taken orally once daily. It can be taken with or without food, but it is recommended to take it at the same time each day to maintain consistent blood sugar control. The tablet should be swallowed whole and not crushed, chewed, or broken. Do not exceed the prescribed dose, and do not stop the medication without consulting your doctor.

Side Effects

Common side effects may include:

• Low blood sugar (hypoglycemia), especially when used with other antidiabetic medicines or alcohol.
• Headache, dizziness, or light-headedness.
• Upper respiratory tract infections (e.g., nasal congestion, sore throat).
• Urinary tract infections and vaginal yeast infections.
• Nausea, vomiting, or diarrhoea.
• Osteoarthritis, arm or leg pain.

If you experience any serious or persistent side effects, consult your doctor immediately.

Precautions

• Pregnancy and Breastfeeding: Not recommended during pregnancy or while breastfeeding.
• Alcohol: Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia.
• Medical Conditions: Inform your doctor if you have kidney or liver issues, heart disease, or a history of urinary tract infections, as dose adjustments or alternative treatments may be necessary.
• Drug Interactions: Disclose all current medications to your doctor to avoid potential interactions, especially with insulin, other anti-diabetic medications, and diuretics.
• Monitoring: Regular monitoring of blood sugar levels is crucial.
• Driving/Machinery: Exercise caution while driving or operating machinery if you experience dizziness or lightheadedness.
• Hygiene: Maintain good personal hygiene to minimize the risk of genital fungal infections and urinary tract infections.
• Type 1 Diabetes: This medication is not suitable for Type 1 Diabetes Mellitus.
• Pediatric Use: Not recommended for children below 12-18 years of age.

Storage

Store SITAZIT D 5/50 MG in a cool and dry place, away from direct sunlight and moisture, at room temperature below 30°C (or between 20-25°C). Keep the medicine out of the sight and reach of children.

Here are frequently asked questions about SITAZIT D 5/50 MG:

1. What is SITAZIT D 5/50 MG used for?

SITAZIT D 5/50 MG is used for the management of type 2 diabetes mellitus in adults, particularly when blood sugar levels are not adequately controlled by metformin alone. It helps lower elevated blood glucose and may also be used in adults with chronic kidney disease to protect kidney function.

2. How does SITAZIT D 5/50 MG work?

This medicine contains two active ingredients: Sitagliptin and Dapagliflozin. Sitagliptin works by increasing the release of insulin from the pancreas after a meal and decreasing the amount of sugar produced by the liver. Dapagliflozin blocks a protein in the kidneys, leading to the removal of excess sugar from the body through urine.

3. What is the usual dosage of SITAZIT D 5/50 MG?

SITAZIT D 5/50 MG is typically taken once daily, with or without food, as prescribed by your doctor. It is recommended to take it at the same time every day for optimal benefits. Do not exceed the recommended dose.

4. What are the possible side effects of SITAZIT D 5/50 MG?

Common side effects may include headache, dizziness, low blood sugar (hypoglycemia), rashes, painful urination, urinary tract infections, upper respiratory tract infections (like nasal congestion and sore throat), and fungal infections in the genital area. Less common side effects can include nausea, vomiting, and abdominal pain.

5. Is SITAZIT D 5/50 MG safe during pregnancy or breastfeeding?

No, SITAZIT D 5/50 MG is generally not recommended during pregnancy or breastfeeding. There is limited information on its effects in pregnant women, and it is not known if it passes into human breast milk, so its safety during lactation is not well-established. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

6. Can SITAZIT D 5/50 MG be taken with other medications?

Caution should be exercised if you are taking other medications. Combining SITAZIT D 5/50 MG with insulin or sulphonylureas may increase the risk of extremely low blood sugar levels. Diuretics (water pills) taken with this medicine may increase the risk of dehydration and low blood pressure. Inform your doctor about all medicines, herbals, or supplements you are taking to avoid potential interactions.

7. What precautions should be taken while using SITAZIT D 5/50 MG?

SITAZIT D 5/50 MG is not for type 1 diabetes. Inform your doctor if you have kidney or liver disease, heart failure, a history of low blood pressure, or stomach/intestine illness. Monitor for symptoms of acute pancreatitis (severe abdominal pain). Maintain good hygiene to prevent genital fungal infections and drink plenty of fluids to prevent dehydration. If you experience dizziness, avoid driving or operating machinery.

8. What should I do if I miss a dose of SITAZIT D 5/50 MG?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

9. How should SITAZIT D 5/50 MG be stored?

Store SITAZIT D 5/50 MG in a cool and dry place below 30°C, away from direct sunlight, moisture, and heat. Keep it out of the reach of children and pets.