Nexovas Tm 25 Mg Tablet (10 Tab)

NEXOVAS TM 25 MG TABLET

NEXOVAS TM 25 MG TABLET is a prescription medication manufactured by Macleods Pharmaceuticals Ltd.

• Composition: Each tablet contains a combination of three active ingredients: Cilnidipine (10 mg), Metoprolol Succinate (25 mg), and Telmisartan (40 mg).

  • Cilnidipine acts as a calcium channel blocker, relaxing blood vessels to promote smooth blood flow.
  • Telmisartan is an angiotensin II receptor blocker (ARB) that further relaxes blood vessels, lowering blood pressure.
  • Metoprolol Succinate is a beta-blocker that slows the heart rate, enabling the heart to pump blood more efficiently throughout the body.

• Uses: This medicine is primarily used for the management of high blood pressure (hypertension). It helps to reduce the risk of associated cardiovascular complications such as heart attack, stroke, and kidney problems. It may also be beneficial for patients with diabetes or an increased risk of cardiovascular diseases.

• Dosage and Administration: NEXOVAS TM 25 MG TABLET should be taken orally once daily, or as prescribed by a healthcare professional. It can be taken with or without food, but it is recommended to take it at the same time each day for optimal results. The tablet should be swallowed whole without crushing, chewing, or breaking it.

• Side Effects: Common side effects may include headache, dizziness, fatigue, low blood pressure, nausea, taste changes, and swelling of the ankles. Serious side effects requiring immediate medical attention include trouble breathing, sudden chest pain, very slow heartbeat, fainting, swelling of the face or throat, yellowing of the skin or eyes, or unusual tiredness.

• Precautions: NEXOVAS TM 25 MG TABLET is not recommended during the second and third trimesters of pregnancy and should be used with caution while breastfeeding. Patients with very low blood pressure, certain heart rhythm problems, severe asthma, serious heart failure, or severe liver disease should not take this medication. Caution is advised for individuals with kidney or liver impairment. Alcohol consumption should be avoided or limited as it may enhance blood pressure-lowering effects. Do not discontinue the medication abruptly without consulting a doctor, as it can lead to a sudden increase in blood pressure. Potential interactions exist with diuretics, NSAIDs, and potassium supplements.

• Storage: Store the medicine in a cool, dry place below 30°C, protected from light and moisture, and out of the reach of children.

What is NEXOVAS TM 25 MG TABLET used for?

NEXOVAS TM 25 MG TABLET is primarily used to manage hypertension (high blood pressure). It helps reduce the risk of heart-related issues, such as heart attacks and strokes, and can also protect against kidney problems linked with hypertension. This medication is beneficial for overall cardiovascular protection and improving blood circulation. It can also be prescribed for patients with diabetes or an increased risk of cardiovascular diseases.

How does NEXOVAS TM 25 MG TABLET work?

NEXOVAS TM 25 MG TABLET is a combination of three active ingredients: Cilnidipine, Telmisartan, and Metoprolol.

• Cilnidipine is a calcium channel blocker that works by acting on the calcium channels of blood vessels, suppressing their contraction and allowing blood to flow more smoothly.
• Telmisartan is an angiotensin II receptor blocker that relaxes blood vessels by blocking the angiotensin II receptor, thereby lowering blood pressure.
• Metoprolol is a beta-blocker that slows down the heart rate, making it easier for the heart to pump blood throughout the body. Together, these components relax and widen blood vessels, slow the heart rate, and improve blood flow, effectively reducing high blood pressure.

What is the usual dosage for NEXOVAS TM 25 MG TABLET?

NEXOVAS TM 25 MG TABLET is typically taken once daily, preferably at the same time each day, or as advised by your doctor. The tablet should be swallowed whole with a glass of water and should not be chewed, bitten, crushed, or broken. It can be taken with or without food, but maintaining a consistent routine is recommended for optimal effectiveness. Your doctor will determine the exact dosage and duration of treatment based on your age, the severity of your condition, and your response to the medication. Do not stop taking the medicine without consulting your doctor.

What are the possible side effects of NEXOVAS TM 25 MG TABLET?

Common side effects may include headache, nausea, dizziness, weakness, decreased blood pressure, slow heart rate, ankle swelling, fatigue, flushing (a warm sensation in the face, ears, neck, and trunk), edema (swelling), taste changes, diarrhea, throat infection, and back pain. Most of these side effects are usually temporary and tend to resolve over time as your body adjusts to the medication.

Serious side effects that require immediate medical attention include trouble breathing, sudden chest pain, very slow heartbeat, fainting, swelling of the face or throat, yellowing of the skin or eyes, or unusual tiredness. In some patients, NEXOVAS TM 25 MG TABLET may also worsen symptoms of heart failure, indicated by swelling in the legs, sudden weight gain, or difficulty breathing.

Is NEXOVAS TM 25 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: NEXOVAS TM 25 MG TABLET is generally not recommended during pregnancy due to a definite risk to the developing baby. If you are pregnant or planning a pregnancy, consult your doctor for safer alternatives. It may only be prescribed in rare, life-threatening situations where the benefits outweigh the risks. Breastfeeding: It is not recommended to use NEXOVAS TM 25 MG TABLET while breastfeeding, as information regarding its use during this period is limited or not available. Consult your healthcare provider for suitable alternatives.

Can NEXOVAS TM 25 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications you are currently taking, especially those for high blood pressure or heart conditions. NEXOVAS TM 25 MG TABLET can interact with certain drugs:

• Diuretics (e.g., furosemide or hydrochlorothiazide) may increase the risk of hypotension and electrolyte imbalances.
• Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, can reduce the blood pressure-lowering effect and increase the risk of kidney impairment.
• Antidepressants like fluoxetine or paroxetine may elevate the levels of metoprolol in the body, potentially leading to increased side effects.
• It is advised to avoid potassium supplements and maintain a consistent intake of potassium-rich foods, as the medication can affect potassium levels. Avoid consuming grapefruit or grapefruit juice, as it may interact with NEXOVAS TM 25.

What precautions should be taken while taking NEXOVAS TM 25 MG TABLET?

• Do not stop taking NEXOVAS TM 25 MG TABLET abruptly without consulting your doctor, as this can lead to a sudden increase in blood pressure, changes in heart rhythm, chest pain, or even a heart attack. Your doctor will gradually lower your dose if discontinuation is necessary.
• This medicine may cause dizziness, so avoid driving or operating heavy machinery until you know how it affects you.
• Avoid or limit alcohol consumption, as it may increase dizziness and enhance the blood pressure-lowering effects of the medication.
• Rise slowly from a lying or sitting position to prevent dizziness caused by a sudden drop in blood pressure (orthostatic hypotension).
• Inform your doctor if you have existing health conditions such as diabetes, circulation problems, asthma, thyroid disorder, adrenal gland tumor, or liver or kidney problems, as dose adjustments or close monitoring may be required. Use with caution in patients with liver or kidney impairment, and it is not recommended for those with severe liver disease.
• Regular monitoring of blood pressure, kidney function, blood sugar levels, and electrolyte levels may be necessary during treatment.
• NEXOVAS TM 25 MG TABLET is not recommended for children. Use with caution in the elderly, as they may be more susceptible to side effects.

What happens if a dose of NEXOVAS TM 25 MG TABLET is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should NEXOVAS TM 25 MG TABLET be stored?

Store NEXOVAS TM 25 MG TABLET in a cool and dry place, away from direct sunlight. It should be kept out of the reach and sight of children. The medicine should be stored below 30°C and protected from light and moisture.