Nevirin Tab

NEVIRIN TAB

Name

Brand Name: Nevirin Tablet

Composition

Nevirin Tablet contains a combination of active ingredients:

• Alpha Lipoic Acid (100mg)
• Folic Acid (1mg) or L-Methyl Folate Calcium
• Methylcobalamin (1500mcg)
• Pregabalin (75mg)
• Pyridoxal 5 Phosphate (1.5mg) or Pyridoxine

Uses

Nevirin Tablet is primarily used to treat neuropathic pain, particularly painful diabetic neuropathy in adults. It also aids in managing and preventing seizures in patients with epilepsy. This medication helps to improve nerve functioning, prevent nerve damage, and relieve symptoms such as sharp pains, tingling, and numbness caused by nerve damage.

Dosage and Administration

This medicine should be taken in the dose and duration recommended by a doctor. It can be taken with or without food, but it is advised to take it at the same time each day to maintain a consistent level of medicine in the body. Patients should not stop taking Nevirin Tablet without consulting their doctor, even if they start feeling better, to avoid withdrawal symptoms.

Side Effects

Common side effects include dizziness, sleepiness, headache, blurred vision, increased appetite, constipation, stomach discomfort, uncoordinated body movements, and tiredness. Other reported side effects may include nausea, vomiting, diarrhoea, stomach upset, peripheral oedema (swelling of lower legs and hands), weight gain, and rash.

Precautions

Nevirin Tablet should not be used if you are allergic to pregabalin, methylcobalamin, alpha-lipoic acid, pyridoxine, folic acid, or any other ingredient. It is not recommended for children below 18 years of age. Pregnant or breastfeeding individuals should consult their doctor before taking this medicine. Patients with diabetes, heart failure, kidney disease, or spinal cord injury should also inform their doctor. Alcohol consumption should be avoided as it may worsen drowsiness and sleepiness. The medicine may cause weight gain.

Storage

Nevirin Tablet should be stored below 30°C.

What is Nevirin Tablet used for?

Nevirin Tablet is a combination medicine primarily used to treat neuropathic pain, which is pain caused by nerve damage. This includes conditions such as diabetic neuropathy, characterized by symptoms like sharp pains, tingling, numbness, and burning sensations in the legs. It is also used for the management of vitamin deficiencies and to support healthy nerve function.

How does Nevirin Tablet work?

Nevirin Tablet contains a combination of ingredients that work together to relieve neuropathic pain and support nerve health. It typically includes Pregabalin, Methylcobalamin (Vitamin B12), Alpha Lipoic Acid, Folic Acid (Vitamin B9), and Pyridoxal-5-phosphate (Vitamin B6).

• Pregabalin reduces pain by modulating calcium channel activity of the nerve cells, thereby decreasing abnormal nerve signals.
• Methylcobalamin (Vitamin B12) helps in the formation and regeneration of nerve cells and protects nerve fibers.
• Alpha Lipoic Acid is a powerful antioxidant that helps protect against oxidative stress and nerve cell damage, and also improves nerve functioning.
• Folic Acid (Vitamin B9) plays a significant role in DNA and amino acid synthesis, which is important for healthy nerve function.
• Pyridoxal-5-phosphate (Vitamin B6) is crucial for various bodily reactions and acts as a coenzyme.

Collectively, these components protect nerve fibers, promote nerve repair, and alleviate the sensation of pain.

What is the usual dosage of Nevirin Tablet?

The dosage and duration of Nevirin Tablet should be determined by a physician based on the patient's age, body weight, and medical condition. It should be taken as advised by your doctor, swallowed whole, and not crushed, chewed, or opened. It can be taken with or without food, but taking it at a consistent time each day is recommended to maintain stable medicine levels in the body. Do not stop taking it without consulting your doctor, even if you feel better.

What are the possible side effects of Nevirin Tablet?

Common side effects of Nevirin Tablet may include dizziness, sleepiness, tiredness, headache, blurred vision, increased appetite, constipation, and stomach discomfort. Some individuals may also experience uncoordinated body movements. If side effects persist or worsen, consult your doctor. Severe, though rare, side effects can include loss of appetite, toxic epidermal necrolysis, yellow skin, allergic reactions, liver inflammation, or Stevens-Johnson syndrome.

Is Nevirin Tablet safe during pregnancy or breastfeeding?

It is generally advised to avoid Nevirin Tablet during pregnancy as there is limited information about its effects on pregnancy. Animal studies have shown harmful effects on developing babies, and it may be unsafe to use during pregnancy. For breastfeeding, a component of Nevirin Tablet is excreted into breast milk, and it is probably unsafe. It is crucial to inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding, so they can weigh the benefits against potential risks.

Can Nevirin Tablet be taken with other medications?

Nevirin Tablet can interact with other medications. It is important to inform your healthcare provider about all prescription, over-the-counter, nutritional or vitamin supplements, and herbal products you are taking. Certain medications, such as St. John's Wort, may interact with Nevirin Tablet and reduce its effectiveness. Medicines used to treat brain-related diseases or movement-related diseases like levodopa or lorazepam may also interact. Methyl folate, one of the components, may interact with anti-seizure medications and antibiotics.

What precautions should be taken with Nevirin Tablet?

Before starting Nevirin Tablet, inform your doctor about any severe liver conditions or if you have previously experienced severe rashes, fever, blistering, mouth soreness, eye inflammation, or swelling after taking similar medication. Patients with diabetes, heart failure, kidney disease, or spinal cord injury should use it with caution. Watch out for signs of liver and skin reactions during the first 18 weeks of treatment; your doctor may monitor liver function and blood count regularly. Nevirin Tablet should not be given to children under 18 years of age. Avoid driving or operating machinery if you experience dizziness, drowsiness, or blurred vision. Alcohol consumption should be avoided as it may worsen certain side effects and cause excessive drowsiness.

What happens if a dose of Nevirin Tablet is missed?

If you miss a dose of Nevirin Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this could increase the risk of side effects. Maintaining a consistent dosing schedule is important for its effectiveness.

How should Nevirin Tablet be stored?

Nevirin Tablet should be stored in a cool and dry place, protected from light, at a temperature not exceeding 30°C. It should be kept out of sight and reach of children and pets. Do not freeze the tablets.