Nucoxia 60 Tablet

Name NUCOXIA 60 TABLET, manufactured by ZYDUS CADILA, contains the active ingredient Etoricoxib.

Composition Each film-coated tablet contains 60 mg of Etoricoxib. Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) and a selective cyclooxygenase-2 (COX-2) inhibitor, which works by blocking the release of prostaglandins responsible for pain, swelling, and inflammation.

Uses NUCOXIA 60 TABLET is prescribed for the relief of pain, swelling, and inflammation associated with:

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Acute gouty arthritis It is also used for the short-term treatment of moderate pain after dental surgery in individuals aged 16 years and above.

Dosage and Administration Take the tablet whole with a glass of water. It can be taken with or without food; taking it on an empty stomach may lead to faster action.

• Osteoarthritis: Typically 30 mg to 60 mg once daily.
• Acute Gouty Arthritis: 120 mg once daily for a maximum of 8 days.
• Post-operative Acute Dental Surgery Pain: Up to 90 mg once daily, limited to a maximum of 3 days. Always follow your doctor's instructions, using the lowest effective dose for the shortest duration necessary, and do not exceed the prescribed dosage.

Side Effects Common side effects may include stomach pain, dry socket, swelling of the legs (edema), dizziness, headache, palpitations (pounding heart), increased blood pressure, shortness of breath, constipation, flatulence, heartburn, diarrhea, indigestion (dyspepsia), nausea, vomiting, general weakness, and flu-like illness.

Precautions

• Do not take if you are allergic to etoricoxib or other NSAIDs, or if you have an active ulcer or bleeding in the stomach/intestine, severe liver or kidney disease, heart failure, peripheral arterial disease, or cerebrovascular disease.
• Use with caution if you have a history of stomach bleeding or ulcer, high blood pressure (especially if uncontrolled), high cholesterol, diabetes, or if you smoke, as it may increase the risk of heart attack or stroke.
• This medicine can mask fever, a sign of infection.
• Consult a doctor before use if pregnant or breastfeeding.
• May cause dizziness and fatigue; avoid driving or operating heavy machinery until you know how it affects you.
• Regular monitoring of blood pressure is recommended during treatment.
• Avoid high doses of aspirin and other anti-inflammatory medicines concurrently; low-dose aspirin for cardiovascular protection may be continued under medical supervision.

Storage Store in a cool and dry place, protected from sunlight and moisture, at temperatures between 10ºC to 25ºC or below 30ºC. Keep out of sight and reach of children.

NUCOXIA 60 TABLET, manufactured by Zydus Cadila, contains Etoricoxib 60mg, a non-steroidal anti-inflammatory drug (NSAID). It is primarily used for pain relief and to reduce inflammation.

What is NUCOXIA 60 TABLET used for?

NUCOXIA 60 TABLET is used to treat pain, swelling, and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and gout. It is also prescribed for short-term relief of moderate pain after dental surgery.

How does NUCOXIA 60 TABLET work?

NUCOXIA 60 TABLET contains etoricoxib, which is a selective COX-2 inhibitor. It works by blocking the release of specific chemical messengers called prostaglandins, which are responsible for causing pain, swelling, and inflammation in the body.

What is the usual dosage of NUCOXIA 60 TABLET?

The usual recommended dose for adults depends on the condition. For osteoarthritis, it is typically 60 mg once daily, which may be increased to a maximum of 90 mg once daily if needed. For rheumatoid arthritis and ankylosing spondylitis, the recommended dose is 90 mg once daily. For acute gouty arthritis, a dose of 120 mg once daily is used for a maximum of 8 days. For pain after dental surgery, the dose is 90 mg once daily, limited to a maximum of 3 days. It should always be taken as advised by your doctor.

What are the possible side effects of NUCOXIA 60 TABLET?

Common side effects include stomach pain, dry socket, swelling of the legs, dizziness, headache, palpitations (pounding heart), increased blood pressure, shortness of breath, constipation, flatulence, heartburn, diarrhoea, indigestion (dyspepsia), nausea, vomiting, general weakness, and flu-like illness. If you experience severe stomach pain, black stools, chest pain, new or worsening ankle swelling, jaundice (yellowing of eyes/skin), or signs of an allergic reaction (e.g., severe rash, swelling of the face/lips/tongue, difficulty breathing), seek immediate medical attention.

Is NUCOXIA 60 TABLET safe during pregnancy or breastfeeding?

NUCOXIA 60 TABLET is generally not recommended during pregnancy, especially in the third trimester, as it may have toxic effects on the fetus. If you are pregnant or planning to become pregnant, consult your doctor. It is also not recommended during breastfeeding, as it is unknown if etoricoxib passes into human milk.

Can NUCOXIA 60 TABLET be taken with other medications?

NUCOXIA 60 TABLET can interact with several medications. Inform your doctor about all medicines, supplements, or herbal products you are taking. Particular caution is advised with blood thinners (e.g., warfarin), diuretics, ACE inhibitors, angiotensin receptor blockers, rifampicin, digoxin, minoxidil, salbutamol, birth control pills, cyclosporine, tacrolimus, and other NSAIDs or high-dose aspirin.

What precautions should be taken while taking NUCOXIA 60 TABLET?

Do not take NUCOXIA 60 TABLET if you are allergic to etoricoxib or other pain relievers (NSAIDs). Inform your doctor if you have a history of stomach ulcers, bleeding, severe liver or kidney disease, or heart problems such as a heart attack, stroke, heart failure, or uncontrolled high blood pressure. Patients who smoke, have diabetes, or high cholesterol should also exercise caution. Avoid alcohol consumption while on this medication. If you experience dizziness or sleepiness, do not drive or operate heavy machinery. Regular monitoring of blood pressure is recommended. This medicine is not for children under 16 years of age.

What happens if a dose of NUCOXIA 60 TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should NUCOXIA 60 TABLET be stored?

NUCOXIA 60 TABLET should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children and pets.