Thyrox 62.5 Mcg Tablet (100 Tab)

THYROX 62.5 MCG TABLET (100 TAB) by MACLEODS PHARMACEUTICALS LTD.

Name

• Brand Name: Thyrox 62.5 Tablet
• Common Name (Active Ingredient): Levothyroxine Sodium (Thyroxine Sodium)

Composition

Each tablet contains 62.5 micrograms (mcg) of Thyroxine Sodium, which is a synthetic form of the thyroid hormone thyroxine (T4).

Uses

Thyrox 62.5 Tablet is primarily prescribed for the management of hypothyroidism, a condition where the thyroid gland does not produce sufficient thyroid hormones. It helps to replace deficient thyroid hormones, regulating metabolism, energy levels, growth, and development. It is also used in the management of other thyroid disorders, including certain types of goitres and thyroid cancer.

Dosage and Administration

This medicine should be taken orally as directed by a healthcare professional. It is typically taken once daily on an empty stomach, ideally 30 minutes to 1 hour before breakfast, swallowed whole with a full glass of water. Do not crush, chew, or split the tablet. The dosage is individualized based on medical condition, age, weight, and response to treatment, requiring regular blood tests to monitor thyroid hormone levels.

Side Effects

Common side effects may include increased sweating and sensitivity to heat, nervousness, anxiety, mood swings, fatigue, muscle weakness, diarrhea, weight loss, tremors, headache, shortness of breath, chest pain, palpitations, increased appetite, and restlessness. More serious side effects, though rare, can include severe allergic reactions, a very high temperature, rapid or irregular heartbeat, low blood pressure, yellowness of the eyes or skin, confusion, or fits.

Precautions

• Allergies: Do not take if allergic to thyroxine or any other tablet components.
• Medical Conditions: Use with caution in patients with heart conditions (e.g., coronary heart disease, hypertension, acute myocardial infarction), adrenal gland disorders, diabetes mellitus, or osteoporosis. Regular monitoring of blood sugar levels is advised for diabetic patients, as Thyrox 62.5 mcg Tablet can affect glycemic control.
• Drug Interactions: Inform your doctor about all medications, supplements, and herbal products you are taking. Antacids, iron supplements, calcium supplements, and multivitamins can interfere with absorption; maintain a gap of at least 4 hours.
• Pregnancy and Breastfeeding: Generally considered safe, but dose adjustments may be necessary.
• Food Interactions: Take on an empty stomach as certain foods (e.g., soybean flour, cottonseed meal, cabbage, cauliflower, walnuts, dietary fiber) may interfere with absorption.

Storage

Store Thyrox 62.5 Tablet in a cool and dry place, below 25°C or 30°C, away from direct light and moisture. Keep out of reach of children and pets. Always check the expiry date before use.

THYROX 62.5 MCG TABLET (100 TAB) is a medication containing Thyroxine sodium, a synthetic version of a hormone naturally produced by the thyroid gland. It is primarily used to treat an underactive thyroid gland.

Here are some frequently asked questions about THYROX 62.5 MCG TABLET:

What is THYROX 62.5 MCG Tablet used for?

THYROX 62.5 MCG Tablet is primarily used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones. It helps to replace the missing hormone, thereby regulating the body's energy and metabolism and relieving symptoms such as tiredness, weight gain, depression, dry skin, and sensitivity to cold. It is also used in the management of other thyroid disorders like goitre and certain types of thyroid cancer.

How does THYROX 62.5 MCG Tablet work?

THYROX 62.5 MCG Tablet contains levothyroxine sodium, which is a synthetic form of the natural thyroid hormone thyroxine (T4). It works by replacing the thyroid hormones that your own thyroid gland cannot produce in sufficient quantities. This helps restore normal hormone levels, supporting proper digestion, muscle function, brain development, and bone health, and regulating overall metabolism.

What is the usual dosage of THYROX 62.5 MCG Tablet?

The dosage of THYROX 62.5 MCG Tablet is highly individualized and determined by your doctor based on your specific condition, age, weight, and response to the medication, as indicated by regular blood tests. Adults typically start with a dose between 50 to 100 micrograms daily, which may be adjusted every 4 to 6 weeks. It is crucial to take the tablet exactly as prescribed by your doctor, usually once daily on an empty stomach, 30 to 60 minutes before breakfast, with a full glass of water. Do not crush, chew, or split the tablet unless advised by a doctor, especially for infants or small children where it can be crushed and mixed with water.

What are the possible side effects of THYROX 62.5 MCG Tablet?

Most side effects occur when the dose is higher than needed and usually resolve once the correct dose is established. Common side effects can include palpitations (irregular heartbeat), vomiting, anxiety, diarrhea, weight loss, tremors, increased appetite, restlessness, increased sweating, sensitivity to heat, headache, nervousness, sleeplessness, and muscle weakness or cramps. More serious but less common side effects can include very high temperature, fast or irregular heart rate, low blood pressure, yellowness in the eye/skin, confusion, or fits, which require immediate medical attention. Long-term use may also reduce bone mineral density, particularly in post-menopausal women.

Is THYROX 62.5 MCG Tablet safe during pregnancy or breastfeeding?

Yes, THYROX 62.5 MCG Tablet is generally considered safe for use during pregnancy, with most studies showing low or no risk to the developing baby. However, if you become pregnant while taking this medicine, you should inform your doctor immediately, as the dose may need to be increased or readjusted due to changes in hormone requirements during pregnancy.

It is also considered safe to use during breastfeeding. Levothyroxine passes into breast milk in very low, clinically insignificant amounts and is not harmful to the baby. Adequate thyroid hormone levels are essential for normal lactation, so maintaining your prescribed dose can help ensure a good milk supply.

Can THYROX 62.5 MCG Tablet be taken with other medications?

THYROX 62.5 MCG Tablet can interact with various medications. It's important to inform your doctor about all medicines, supplements, and herbal products you are taking. Some medications, such as antacids, iron supplements, calcium supplements (including those in multivitamins), sucralfate, phosphate binders, and bile acid sequestrants, can decrease the absorption of levothyroxine, making it less effective. These should be taken at least 4 hours apart from THYROX 62.5 MCG Tablet. Oral hormonal contraceptives may increase thyroid hormone binding, potentially requiring a dose adjustment of THYROX. Antiepileptic medicines like phenytoin and carbamazepine may also affect thyroid hormone metabolism. Diabetic patients should be cautious as THYROX may affect blood sugar levels, necessitating adjustment of anti-diabetic medications.

What precautions should be taken?

Do not use THYROX 62.5 MCG Tablet for weight loss, as normal doses are ineffective for this purpose, and large doses can cause serious or fatal side effects. It should be taken on an empty stomach, ideally 30-60 minutes before food, milk, or caffeinated drinks, as these can interfere with absorption. Foods like soy products, cottonseed meal, cabbage, cauliflower, walnuts, and dietary fiber can also reduce absorption and should be avoided for a few hours around dosing. Caution is advised if you have pre-existing heart conditions, adrenal gland disorders, or diabetes, as dose adjustments or close monitoring may be necessary. Regular blood tests are essential to monitor thyroid hormone levels and adjust the dosage as needed.

What happens if a dose is missed?

If you miss a dose of THYROX 62.5 MCG Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. It's important to take this medicine regularly as prescribed by your doctor.

How should it be stored?

THYROX 62.5 MCG Tablet should be stored in a cool, dry place, ideally below 25°C or 30°C, away from direct sunlight and moisture. Keep the medicine in a tightly sealed container and out of the reach of children and pets. Always check the expiry date before use.