Penegra 50 Tablet (4 Tab)

PENEGRA 50 TABLET is a medication manufactured by ZYDUS HEALTHCARE LIMITED, primarily used to treat erectile dysfunction (ED) in men. It is also prescribed for pulmonary arterial hypertension (PAH).

Name

• Common Name: Sildenafil
• Brand Name: Penegra 50 Tablet

Composition

PENEGRA 50 TABLET contains Sildenafil (50 mg) as its active ingredient. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor.

Uses

PENEGRA 50 TABLET is primarily used for:

• Erectile Dysfunction (ED): It helps men achieve and maintain an erection by increasing blood flow to the penis when sexually stimulated.
• Pulmonary Arterial Hypertension (PAH): It works by relaxing blood vessels, increasing blood supply to the lungs, and reducing the heart's workload.

Dosage and Administration

For erectile dysfunction, the typical dosage is one 50 mg tablet taken orally with water approximately 30-60 minutes before sexual activity. It should not be taken more than once a day. The tablet can be taken with or without food, though high-fat meals may delay its effect. Your doctor may adjust the dose based on individual response. For pulmonary arterial hypertension, the dosage is typically 20 mg three times daily. Tablets should be swallowed whole and not chewed, crushed, or broken.

Side Effects

Common side effects may include:

• Headache
• Flushing (sense of warmth)
• Dizziness
• Indigestion or stomach upset
• Blurred vision
• Nasal congestion
• Muscle pain

Serious side effects, though rare, can include sudden vision or hearing loss, chest pain, irregular heartbeat, or a prolonged and painful erection (priapism). Seek immediate medical attention if an erection lasts longer than 4 hours.

Precautions

Do not take PENEGRA 50 TABLET if you are allergic to sildenafil or are taking nitrate medications (for chest pain/angina) or riociguat (for PAH), as this can cause a dangerous drop in blood pressure. It is contraindicated in individuals with severe heart or liver problems, a recent history of stroke or heart attack, low blood pressure, or certain inherited eye diseases. Alcohol consumption should be avoided as it may impair erection and increase side effects like dizziness. PENEGRA 50 TABLET is not recommended for women or individuals under 18 years of age. Inform your doctor about any underlying health conditions, especially heart, kidney, or eye problems.

Storage

Store PENEGRA 50 TABLET in a cool, dry place, protected from direct sunlight and moisture, ideally between 10ºC to 25ºC or below 30ºC. Keep it out of the sight and reach of children.

Penegra 50 Tablet, which contains the active ingredient Sildenafil, is primarily used to treat erectile dysfunction (ED) in men. Here are some frequently asked questions about this medication:

What is Penegra 50 Tablet used for?

Penegra 50 Tablet is used to treat erectile dysfunction (impotence) in men. This condition is characterized by the inability to achieve or maintain an erection firm enough for satisfactory sexual performance.

How does Penegra 50 Tablet work?

Penegra 50 Tablet contains Sildenafil, which belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow helps a man achieve and maintain an erection. It's important to note that Penegra does not cure ED, increase sexual desire, or cause an erection without sexual stimulation.

What is the usual dosage of Penegra 50 Tablet?

For erectile dysfunction, the usual recommended dose is 50 mg, taken orally as needed, approximately one hour before sexual activity. However, it can be taken anywhere from 30 minutes to 4 hours before sexual activity. Do not take more than one dose within a 24-hour period. Depending on effectiveness and how well you tolerate it, your doctor may adjust the dose to 25 mg or 100 mg.

What are the possible side effects of Penegra 50 Tablet?

Common side effects may include headache, flushing (feeling of warmth), indigestion or heartburn, nasal congestion, dizziness, and changes in vision such as blurred vision or a blue tinge to objects.

More serious side effects, though rare, require immediate medical attention. These include sudden severe loss of vision, sudden decrease or loss of hearing (sometimes with ringing in the ears or dizziness), an erection that is painful or lasts longer than 4 hours (priapism), chest pain, severe low blood pressure, or symptoms of an allergic reaction (rash, hives, swelling of the face, lips, tongue, or throat, difficulty breathing).

Is Penegra 50 Tablet safe during pregnancy or breastfeeding?

Penegra 50 Tablet is specifically intended for use in men to treat erectile dysfunction and is not indicated for use in women.

Can Penegra 50 Tablet be taken with other medications?

You must not take Penegra 50 Tablet if you are taking medications containing nitrates (often prescribed for chest pain or heart problems, like nitroglycerin or isosorbide) or soluble guanylate cyclase (sGC) stimulators like riociguat, as this combination can cause a dangerous and sudden drop in blood pressure.

Inform your doctor about all other medications, vitamins, and herbal supplements you are taking, especially alpha-blockers (for prostate issues or high blood pressure), certain HIV medicines, some antifungal medications (e.g., ketoconazole), or other blood pressure medications, as these can interact with sildenafil. It is also advisable to limit or avoid alcohol consumption and grapefruit juice, as they can increase the risk of side effects.

What precautions should be taken while using Penegra 50 Tablet?

Before taking Penegra, inform your doctor about any existing medical conditions, particularly heart problems (such as a history of heart attack, stroke, irregular heartbeat, angina, or high/low blood pressure), kidney or liver disease, bleeding disorders, stomach ulcers, or certain eye conditions (e.g., retinitis pigmentosa, or a history of sudden vision loss). If you experience dizziness or changes in vision, avoid driving or operating heavy machinery. Penegra does not offer protection against sexually transmitted diseases (STDs) or pregnancy.

What happens if a dose is missed?

Since Penegra 50 Tablet is taken on an as-needed basis for erectile dysfunction, it is unlikely you will miss a regular dose. Take it when you remember, but ensure you do not exceed one dose per day.

How should Penegra 50 Tablet be stored?

Store Penegra 50 Tablet at room temperature, ideally between 20°C to 25°C (68°F to 77°F), away from moisture, excessive heat, and direct light. Keep the medication in its original packaging and out of the reach of children. Do not use the medicine beyond its expiration date, which is typically about two to three years from the manufacturing date.