Sitaclass Dm 100/10/1000

SITACLASS DM 100/10/1000 Tablet

Name:

• Brand Name: Sitaclass DM 100/10/1000 Tablet

Composition: SITACLASS DM 100/10/1000 Tablet is a fixed-dose combination medication containing three active ingredients:

• Dapagliflozin (10 mg)
• Metformin (1000 mg)
• Sitagliptin (100 mg)

Uses: This medication is prescribed for the management of type 2 diabetes mellitus in adults. It is used when diet, exercise, and therapy with conventional medicines do not result in an adequate response. SITACLASS DM helps to control high blood sugar levels by improving blood sugar control, reducing insulin resistance, and promoting glucose excretion. It may also aid in weight management and help reduce cardiovascular risk in some patients.

Dosage and Administration: SITACLASS DM 100/10/1000 Tablet should be swallowed whole with water, without crushing or chewing. It can be taken with or without food, but taking it after meals may reduce nausea. The exact dose and frequency should be determined by a doctor, and the recommended dose should not be exceeded.

Side Effects:

• Common Side Effects: Urinary tract infection, nasal congestion, sore throat, upper respiratory tract infection, genital fungal infections, diarrhea, headache, nausea, influenza, and back pain. Diarrhea and nausea can sometimes be managed by taking the tablet with food.
• Serious Side Effects: Low blood sugar (hypoglycemia) and, rarely, lactic acidosis. Symptoms of low blood sugar include anger, shaking, fast heartbeat, confusion, or sweating.

Precautions:

• Renal and Hepatic Impairment: Not recommended for individuals with severe renal impairment or those undergoing dialysis due to the metformin component. Individuals with liver diseases should also avoid this medication.
• Pregnancy and Breastfeeding: Consult a doctor before using during pregnancy or breastfeeding to assess potential risks.
• Alcohol: Limit alcohol consumption as it can increase the risk of lactic acidosis.
• Drug Interactions: May interact with medications like insulin, sulfonylureas, diuretics, certain heart medicines (e.g., captopril, enalapril), cimetidine, and birth control pills. Inform your doctor about all medicines, supplements, and herbal tonics being taken.

Storage: Store SITACLASS DM below 30°C in a cool, dry place, away from direct heat and sunlight. Keep it out of the reach of children and pets.

SITACLASS DM 100/10/1000: Frequently Asked Questions

SITACLASS DM 100/10/1000 is a medication used to manage type 2 diabetes mellitus in adults. It contains a combination of three active ingredients: Dapagliflozin (10 mg), Metformin (1000 mg), and Sitagliptin (100 mg). This medication works through multiple mechanisms to help control blood sugar levels when diet, exercise, and therapy with conventional medicines are not sufficient.

What is SITACLASS DM 100/10/1000 used for?

SITACLASS DM 100/10/1000 is primarily used for the management of type 2 diabetes mellitus in adults. It helps improve blood sugar control as an adjunct to diet and exercise. It is also used in patients who need enhanced blood sugar management beyond dual therapy, and it can help lower the risk of heart failure and diabetic kidney disease in some individuals. It is not intended for the management of type 1 diabetes or diabetic ketoacidosis.

How does SITACLASS DM 100/10/1000 work?

This medicine combines three different agents to control blood sugar levels:

• Dapagliflozin (an SGLT2 inhibitor) works by blocking the reabsorption of glucose in the kidneys, leading to more sugar being passed out in the urine, thereby reducing blood sugar levels.
• Metformin (a biguanide) reduces the amount of glucose produced by the liver and delays sugar absorption from the intestines. It also improves the body's sensitivity to insulin, promoting better glucose uptake by muscles and tissues.
• Sitagliptin (a DPP-4 inhibitor) increases the levels of certain natural substances (incretins) that help the pancreas release more insulin and decrease glucagon levels when blood sugar is high.

What is the usual dosage for SITACLASS DM 100/10/1000?

The daily dosage of SITACLASS DM 100/10/1000 is determined by your doctor, considering your health condition and how you respond to the medicine. It is typically taken orally with meals, usually once or twice a day, as prescribed. It is crucial never to alter the prescribed dose without consulting your doctor. The tablet should be swallowed whole and not crushed, broken, or chewed.

What are the possible side effects of SITACLASS DM 100/10/1000?

Common side effects can include female genital mycotic infections, nasopharyngitis (inflammation of the throat and nasal passages), urinary tract infections, diarrhea, headache, nausea, and vomiting. Less common but serious side effects can include lactic acidosis, ketoacidosis, severe joint pain, pancreatitis, and allergic reactions. If you experience any severe or persistent side effects, you should consult your doctor immediately.

Is SITACLASS DM 100/10/1000 safe during pregnancy or breastfeeding?

SITACLASS DM 100/10/1000 is generally not recommended during pregnancy or breastfeeding due to limited safety data. It is important to consult your doctor if you are pregnant, planning to conceive, or breastfeeding before taking this medication. Metformin, one of the components, may be used during pregnancy, but other antidiabetic drugs are often avoided.

Can SITACLASS DM 100/10/1000 be taken with other medications?

SITACLASS DM 100/10/1000 can interact with certain medications. Inform your doctor about all medicines, including herbal tonics and supplements, you are taking. Interactions can occur with:

• Thiazide and Loop Diuretics (e.g., hydrochlorothiazide, furosemide) which may increase the risk of dehydration, low blood pressure, or lactic acidosis.
• Carbonic Anhydrase Inhibitors (e.g., acetazolamide) which may increase the risk of lactic acidosis.
• Insulin and Insulin Secretagogues (e.g., glipizide) which may increase the risk of hypoglycemia.
• Corticosteroids. Always inform your doctor or pharmacist about all other medicines or supplements you are using.

What precautions should be taken with SITACLASS DM 100/10/1000?

Several precautions should be taken while on this medication:

• Renal and Hepatic Impairment: It is not recommended for individuals with severe renal impairment or those undergoing dialysis, or for people with liver diseases, due to potential risks like lactic acidosis.
• Alcohol Consumption: Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis.
• Dehydration: Drink plenty of fluids, especially in hot weather or when sick, to prevent dehydration.
• Hypoglycemia: Be aware of the signs of low blood sugar (sweating, shakiness, dizziness, hunger, confusion, headaches) and always carry a source of sugar for immediate relief.
• Urinary and Genital Infections: Maintain good hygiene as some people may develop fungal infections in the genital area or urinary tract infections.
• Medical Procedures: Inform your doctor if you are going for an operation, dental work, or any X-ray procedure requiring a dye injection, as you may need to stop Metformin temporarily.

What happens if a dose of SITACLASS DM 100/10/1000 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can cause your sugar level to fall rapidly.

How should SITACLASS DM 100/10/1000 be stored?

SITACLASS DM 100/10/1000 should be stored at room temperature (20-25°C) away from moisture and heat. Keep it out of the sight and reach of children.