Susten 200 Inj

SUSTEN 200 INJ

SUSTEN 200 INJ is a medication primarily used to supplement the body with progesterone, a vital female hormone. It is manufactured by Sun Pharmaceutical Industries Ltd..

Composition

• Active Ingredients: Progesterone (200 mg).
• Excipients: Benzyl Alcohol is also listed as a component, serving as a solvent or antimicrobial preservative.

Uses

SUSTEN 200 INJ is prescribed for various gynecological and reproductive conditions:

• Support of Early Pregnancy: Especially in women with progesterone deficiency or a history of repeated miscarriages. It helps sustain pregnancy by increasing the thickness of the uterine wall and preventing contractions that could lead to early pregnancy loss.
• Assisted Reproductive Technology (ART): Provides luteal phase support in treatments like in vitro fertilization (IVF) to facilitate successful embryo implantation.
• Menstrual Cycle Regulation: Manages secondary amenorrhea (absence of menstruation) and regulates irregular menstrual cycles by stabilizing hormonal imbalances.
• Abnormal Uterine Bleeding: Controls and treats dysfunctional uterine bleeding caused by hormonal imbalance.
• Hormone Replacement Therapy (HRT): Used in conjunction with estrogen to alleviate menopausal symptoms and prevent endometrial hyperplasia.
• Preparation for Implantation: Prepares the uterine lining for embryo implantation.

Dosage and Administration

SUSTEN 200 INJ is administered by a healthcare professional as an intramuscular or subcutaneous injection. The specific dose and frequency depend on the patient's condition, age, and body weight, as determined by a doctor. Rotating injection sites is recommended to prevent skin irritation.

Side Effects

Common Side Effects include:

• Injection site reactions (pain, redness, soreness, itching, swelling)
• Bloating, nausea, vomiting, diarrhea
• Headache, dizziness, drowsiness
• Breast tenderness or enlargement
• Fluid retention (swelling in hands, ankles, feet)
• Mood changes, irritability, depression
• Vaginal bleeding or discharge
• Hair loss, abnormal hair growth, darkening of facial skin
• Stomach cramps, back pain, leg cramps, pelvic pain, fatigue, changes in body weight

Serious Side Effects (consult a doctor immediately if experienced) include:

• Severe allergic reactions (rash, swelling, difficulty breathing)
• Severe depression
• Jaundice (yellow skin and eyes)
• Blood clots
• Breast lumps
• Painful urination
• Memory loss
• Symptoms of overstimulation of the ovaries (lower stomach pain, thirst, low urine output, weight gain).

Precautions

• Allergies: Not recommended for individuals allergic to progesterone or benzyl alcohol.
• Medical Conditions: Inform your doctor about pre-existing conditions such as liver, kidney, or heart problems, diabetes, high blood pressure, asthma, epilepsy, or migraine headaches.
• Contraindications: Avoid use in cases of breast, ovarian, or uterine cancer, undiagnosed vaginal bleeding, blood clotting disorders, porphyria, or a history of ectopic pregnancy or severe itching during previous pregnancies.
• Pregnancy and Breastfeeding: Commonly used to support early pregnancy, but consultation with a doctor is essential. Not recommended for breastfeeding women.
• Alcohol: Caution is advised with alcohol intake.
• Driving/Operating Machinery: Avoid if experiencing drowsiness.
• Children: Not recommended for use in children and adolescents under 18 years of age.

Storage

Store SUSTEN 200 INJ in a cool and dry place, ideally below 30°C. Keep it away from direct sunlight, heat, dampness, and moisture. Do not freeze. Ensure it is kept out of sight and reach of children.

SUSTEN 200 INJ by SUN PHARMA VV is a medication containing progesterone, a female hormone. It is primarily used to address various hormonal imbalances and support reproductive health. Below are frequently asked questions about this medicine.

1. What is Susten 200 Injection used for?

Susten 200 Injection is used for several conditions related to female hormonal health. It is commonly prescribed for the maintenance of early pregnancy, treatment of threatened abortion, dysfunctional uterine bleeding, and amenorrhoea (absence of menstrual periods). It also provides luteal phase support in assisted reproductive technologies like in vitro fertilisation (IVF) to help with successful implantation and prevent miscarriages due to luteal phase defect. Additionally, it can be used as part of hormone replacement therapy and to regulate menstrual cycles.

2. How does Susten 200 Injection work?

Susten 200 Injection contains progesterone, a natural female sex hormone. It works by increasing the levels of progesterone in the body. This hormone is essential for preparing the uterus for pregnancy by thickening the uterine lining (endometrium) to support the implantation of a fertilized egg and maintaining a healthy environment for fetal development. It also helps prevent uterine contractions that could lead to early pregnancy loss, regulates the menstrual cycle, and balances other reproductive hormones.

3. What is the usual dosage for Susten 200 Injection?

Susten 200 Injection is administered as an intramuscular injection by a healthcare professional (doctor or nurse). The specific dose and duration of treatment will be determined by your doctor, depending on the condition being treated. It should not be self-administered.

4. What are the possible side effects of Susten 200 Injection?

Common side effects may include injection site reactions (pain, redness, swelling), headache, back pain, dizziness, weight gain, vaginal discharge, stomach cramps, abdominal pain or discomfort, nausea, vomiting, breast pain or tenderness, fatigue, mood swings, irritability, and sleep disturbances. Most of these side effects are temporary and usually resolve over time. Less common but more serious side effects can include vision abnormalities (blurred or double vision, loss of vision), blood clots, chest pain, difficulty passing urine, and severe allergic reactions. If you experience persistent or severe side effects, consult your doctor.

5. Is Susten 200 Injection safe during pregnancy or breastfeeding?

During pregnancy, Susten 200 Injection is commonly used to support early pregnancy and prevent miscarriages, especially in women with progesterone deficiency or a history of recurrent miscarriages. It can be used during the first three months of pregnancy. However, there are some reports indicating it might be considered unsafe in some cases, with potential risks to the developing baby, and its use during pregnancy should always be determined and closely monitored by a healthcare professional, weighing the benefits against potential risks.

For breastfeeding mothers, Susten 200 Injection is generally not recommended. Limited human data suggests the drug may pass into breast milk and could potentially harm the baby. Your doctor will assess whether the medicine can be taken while breastfeeding.

6. Can Susten 200 Injection be taken with other medications?

Yes, Susten 200 Injection can interact with other medications. It is crucial to inform your doctor about all medicines you are currently taking, including prescription drugs, over-the-counter medications, herbal supplements, and vitamins. Specific drug interactions have been noted with certain antiepileptics (e.g., carbamazepine, phenytoin), rifampicin, antifungal agents (e.g., griseofulvin, ketoconazole), St. John's wort, cyclosporine, and antidiabetic agents (e.g., glimepiride, metformin). Your doctor may need to adjust dosages or monitor you more frequently if you are taking these medications concurrently.

7. What precautions should be taken while using Susten 200 Injection?

Several precautions should be observed:

• Do not self-administer the injection.
• Inform your doctor about any known allergies, especially to progesterone or components like peanut oil.
• Discuss your medical history with your doctor, particularly if you have liver, kidney, or heart problems, diabetes, asthma, epilepsy, migraine headaches, porphyria, breast cancer, ovarian cancer, uterine cancer, blood clot issues, or unexplained vaginal bleeding.
• Avoid driving or operating heavy machinery if you experience dizziness or drowsiness after the injection.
• Regular medical tests, such as womb checks, may be advised before and during treatment.
• Alcohol consumption is generally not recommended or should be limited while using this medication; consult your doctor for advice.
• Susten 200 Injection is intended for use in female patients only and is not recommended for children under 18 years of age.

8. What happens if a dose of Susten 200 Injection is missed?

If you miss a dose of Susten 200 Injection, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Always follow your doctor's specific instructions regarding missed doses.

9. How should Susten 200 Injection be stored?

Susten 200 Injection should be stored in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. The recommended storage temperature is typically between 10ºC to 25ºC or below 30ºC, and it should not be frozen.