Syntran Sb 130 Mg Capsules 30 Capsules

SYNTRAN SB 130 MG CAPSULES

Name: SYNTRAN SB 130 MG CAPSULES (common name: Itraconazole)

Composition: Each capsule contains Itraconazole 130 mg. Itraconazole is a triazole antifungal agent.

Uses: SYNTRAN SB 130 MG CAPSULES are primarily used to treat a wide range of fungal and yeast infections. This includes infections affecting the mouth and throat (oral thrush), vagina (vaginal thrush), skin (such as ringworm, athlete's foot, jock itch), and nails (fingernails and toenails). It is also effective against systemic fungal infections, including those of the lungs, and infections caused by fungi like Trichophyton spp., Microsporum spp., Epidermophyton floccosum, Histoplasma, Aspergillus, and Blastomyces. The medication works by inhibiting the production of ergosterol, a crucial component of fungal cell membranes, which leads to the weakening and death of the fungal cells.

Dosage and Administration: SYNTRAN SB 130 MG CAPSULES should be taken orally, exactly as prescribed by a doctor. It is recommended to take the capsule with food to enhance absorption and prevent stomach upset. The capsule should be swallowed whole with water and not crushed or chewed. The dosage and duration of treatment depend on the type and severity of the infection. It is important not to discontinue the medication abruptly, even if symptoms improve, to prevent the infection from recurring or becoming resistant.

Side Effects: Common side effects may include headache, nausea, diarrhea, fatigue, cough, cold, back pain, and stomach pain. Other reported common side effects are dizziness, abdominal pain, constipation, and dyspepsia. More serious but less common side effects that require immediate medical attention include severe allergic reactions (skin rash, swelling of the lips, face, throat, difficulty breathing), liver problems (yellowing of eyes or skin, dark urine, pale stools, stomach pain, loss of appetite, unusual tiredness), irregular heartbeat, and symptoms of heart failure (shortness of breath, weight gain, swelling).

Precautions:

• Pregnancy and Breastfeeding: SYNTRAN SB 130 MG CAPSULES are generally not recommended during pregnancy (Pregnancy Category C) as they may harm the unborn baby, especially in the first trimester. It is also advised to use with caution or avoid during breastfeeding, as the medication can pass into breast milk.
• Liver and Kidney Conditions: Caution is advised for patients with pre-existing liver or kidney diseases, and liver function may be monitored.
• Heart Conditions: Patients with a history of heart failure should avoid this medication due to the risk of severe adverse effects.
• Drug Interactions: Avoid taking with fentanyl (a strong opioid painkiller) due to severe breathing problems. Antacids should not be taken within 2 hours of SYNTRAN SB 130 MG CAPSULES, as they can affect absorption. If taking stomach acid suppressors, it may be advised to take the capsule with cola for better absorption.
• Driving: Dizziness or blurred vision may occur, so caution is advised when driving or operating machinery.

Storage: Store SYNTRAN SB 130 MG CAPSULES at room temperature, not exceeding 30 degrees Celsius. Keep the packaging away from direct sunlight and damp areas. Ensure the container is tightly sealed and keep the medicine out of reach of children.

SYNTRAN SB 130 MG CAPSULES, manufactured by Glenmark Laboratories, contains the active ingredient Itraconazole. This medication is primarily used to treat a wide range of fungal and yeast infections.

Here are some frequently asked questions about SYNTRAN SB 130 MG CAPSULES:

What is SYNTRAN SB 130 MG CAPSULES used for?

SYNTRAN SB 130 MG CAPSULES is an antifungal medicine used to treat various fungal and yeast infections in different parts of the body. These include infections of the mouth, throat (oral thrush), vagina (vaginal thrush), skin (like ringworm, athlete's foot, jock itch), nails (fingernails and toenails), and internal organs such as the lungs (e.g., aspergillosis, histoplasmosis). It can also be used for systemic fungal infections that affect organs like the brain or heart.

How does SYNTRAN SB 130 MG CAPSULES work?

This medicine works by stopping the growth of fungi. Its active ingredient, Itraconazole, inhibits the production of ergosterol, a vital component of fungal cell membranes. By damaging the fungal cell membranes, it causes the cell's contents to leak out, which ultimately kills the fungi and helps to clear the infection.

What is the usual dosage for SYNTRAN SB 130 MG CAPSULES?

The dosage and duration of treatment are determined by your doctor based on the type and severity of the infection and your response to the medication. It is usually taken with food, preferably at the same time every day, and swallowed whole without crushing or chewing. It is crucial to complete the full course of treatment as prescribed, even if your symptoms improve, to prevent the infection from returning or developing resistance.

What are the possible side effects of SYNTRAN SB 130 MG CAPSULES?

Common side effects can include nausea, headache, stomach pain or discomfort, vomiting, diarrhea, and dizziness. More serious but less common side effects that require immediate medical attention include severe allergic reactions (e.g., skin rash, difficulty breathing, swelling of the face/lips/tongue), symptoms of liver problems (yellowing of eyes/skin, dark urine, pale stools, severe stomach pain, unusual fatigue), irregular heartbeat, nerve pain, or hearing loss.

Is SYNTRAN SB 130 MG CAPSULES safe during pregnancy or breastfeeding?

SYNTRAN SB 130 MG CAPSULES is generally not recommended during pregnancy as it is a pregnancy category C drug and may pose risks to the unborn baby, including severe birth defects at high doses. It is also not recommended for use during breastfeeding because the medicine may pass into breast milk and potentially harm the infant. Always consult your doctor to discuss the risks and benefits if you are pregnant, planning to become pregnant, or breastfeeding.

Can SYNTRAN SB 130 MG CAPSULES be taken with other medications?

Several medications can interact with SYNTRAN SB 130 MG CAPSULES. Avoid taking antacids or other medicines that reduce stomach acidity within 1-2 hours of taking SYNTRAN SB, as they can interfere with its absorption. Certain antibiotics (e.g., rifampicin), anti-seizure medicines (e.g., carbamazepine), antiviral medicines (e.g., efavirenz), and herbal supplements like St. John's Wort may reduce its effectiveness. Concomitant use with fentanyl (a strong painkiller) can cause severe breathing complications. Always inform your doctor about all medications, vitamins, and herbal supplements you are currently taking to avoid potential interactions.

What precautions should be taken while using SYNTRAN SB 130 MG CAPSULES?

Inform your doctor if you have any pre-existing medical conditions, especially liver problems, heart conditions (such as heart failure or irregular heartbeats), or kidney issues. Your doctor may monitor your liver function, especially during prolonged treatment. Avoid alcohol consumption while on this medication. If you experience dizziness or hearing loss, avoid driving or operating heavy machinery. Reliable contraception should be used to prevent pregnancy during treatment.

What happens if a dose of SYNTRAN SB 130 MG CAPSULES is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should SYNTRAN SB 130 MG CAPSULES be stored?

Store SYNTRAN SB 130 MG CAPSULES at room temperature, ideally not exceeding 30 degrees Celsius, in a cool and dry place. Keep it away from direct sunlight and moisture. Ensure the container is tightly sealed and keep it out of the reach of children.