Vildamac Trio 1000 Tab

VILDAMAC TRIO 1000 TAB

Name

• Brand Name: Vildamac Trio 1000 Tablet
• Manufacturer: Macleods Pharmaceuticals Ltd.

Composition Vildamac Trio 1000 Tablet is a combination medicine containing three active ingredients:

• Dapagliflozin (10 mg)
• Metformin (1000 mg)
• Vildagliptin (100 mg)

Uses Vildamac Trio 1000 Tablet is primarily used for the management of Type 2 Diabetes Mellitus in adults. It works by improving insulin sensitivity, reducing glucose production, and increasing glucose excretion through urine. Additionally, this medicine helps to minimize the risk of cardiovascular death and hospitalization due to heart failure in adults with heart problems, and aids in reducing the risk of severe kidney disease in adults with chronic kidney disease.

Dosage and Administration The tablet should be swallowed whole with or without food, as advised by a doctor. It should not be crushed, broken, or chewed. The specific dose and duration of treatment will be determined by a healthcare professional.

Side Effects Common side effects may include:

• Vomiting, nausea, abdominal pain
• Headache
• Frequent urination, urinary tract infection
• Vaginal yeast infection
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Diarrhea, gas, constipation Serious side effects, though less common, can include lactic acidosis, especially in patients with kidney or liver insufficiency.

Precautions Consult a doctor if you are pregnant or breastfeeding, as its use is generally not recommended in these situations. Patients with liver disease should avoid this medicine, and caution is advised for those with kidney disease, heart problems, or hypertension. Alcohol consumption should be avoided as it increases the risk of hypoglycemia and lactic acidosis. Inform your doctor about all existing medical conditions and other medications, including herbal supplements, to avoid potential interactions. This medicine may interact with insulin or insulin secretagogues, increasing the risk of hypoglycemia, and with diuretics, which may increase the risk of dehydration and low blood pressure.

Storage Store Vildamac Trio 1000 Tablet at room temperature, ideally below 30°C, protected from light and moisture. Keep the medicine out of the sight and reach of children.

VILDAMAC TRIO 1000 TAB is a medication used to manage Type 2 Diabetes Mellitus. Below are some frequently asked questions about this medicine.

What is VILDAMAC TRIO 1000 TAB used for?

VILDAMAC TRIO 1000 TAB is primarily used to control high blood sugar levels in adults with Type 2 Diabetes Mellitus. It is used as part of a treatment program that includes diet and exercise. This medicine also helps reduce the risk of cardiovascular death and hospitalization due to heart failure, and can minimize the risk of severe kidney disease in adults who have these conditions in addition to Type 2 Diabetes.

How does VILDAMAC TRIO 1000 TAB work?

VILDAMAC TRIO 1000 TAB is a combination of three antidiabetic agents: Dapagliflozin, Vildagliptin, and Metformin.

• Dapagliflozin works by increasing the excretion of glucose through the urine, helping to remove excess sugar from the body.
• Vildagliptin enhances the body's natural substances (incretins) that stimulate the pancreas to release more insulin when blood sugar is high and signals the liver to reduce sugar production.
• Metformin decreases the amount of glucose produced by the liver, reduces glucose absorption from the intestines, and improves the body's sensitivity to insulin.

What is the usual dosage for VILDAMAC TRIO 1000 TAB?

The dosage of VILDAMAC TRIO 1000 TAB is determined by your doctor based on your individual condition. It should be taken as advised by your healthcare provider, usually with food. The tablet should be swallowed whole and not crushed, broken, or chewed.

What are the possible side effects of VILDAMAC TRIO 1000 TAB?

Common side effects may include vomiting, nausea, abdominal pain, headache, frequent urination, vaginal yeast infection, nasopharyngitis (inflammation of the throat and nasal passages), urinary tract infection, and diarrhea. More serious but less common side effects can include lactic acidosis (especially in patients with kidney or liver problems) and acute pancreatitis. Low blood sugar (hypoglycemia) can also occur, particularly if taken with other antidiabetic medicines, alcohol, or if meals are skipped.

Is VILDAMAC TRIO 1000 TAB safe during pregnancy or breastfeeding?

Pregnancy: VILDAMAC TRIO 1000 TAB may be unsafe to use during pregnancy. While human studies are limited, animal studies have indicated harmful effects on the developing baby. It is crucial to consult your doctor if you are pregnant or planning pregnancy. Breastfeeding: This medicine is probably unsafe during breastfeeding as it may pass into breastmilk and potentially harm the baby. Consult your doctor if you are breastfeeding.

Can VILDAMAC TRIO 1000 TAB be taken with other medications?

VILDAMAC TRIO 1000 TAB can interact with other medications. It is important to inform your doctor about all prescription drugs, over-the-counter medicines, herbal products, and supplements you are taking. Specific interactions include:

• Insulin or insulin secretagogues: May increase the risk of hypoglycemia, potentially requiring a lower dose of these medications.
• Diuretics: Combining with diuretics may increase the risk of dehydration and low blood pressure.
• Cationic medications (e.g., amiloride, digoxin, trimethoprim): Metformin, a component, can increase their plasma concentrations.
• Iodinated contrast agents: May lead to acute kidney failure and lactic acidosis; temporary discontinuation of VILDAMAC TRIO 1000 TAB may be advised during procedures involving these agents.
• CYP3A4 Inducers (e.g., rifampicin): May reduce the effectiveness of vildagliptin, another component.

What precautions should be taken while taking VILDAMAC TRIO 1000 TAB?

Before starting this medication, inform your doctor if you have kidney or liver problems, heart problems, hypertension, or a history of urinary tract infections. Avoid alcohol consumption as it can increase the risk of hypoglycemia and lactic acidosis. Maintain good hygiene to prevent fungal infections and drink plenty of fluids to stay hydrated. Regularly monitor your blood sugar levels. Do not stop taking the medicine abruptly, even if your blood sugar levels are controlled, as this can lead to complications. VILDAMAC TRIO 1000 TAB is not recommended for children under 18 years of age. It may cause dizziness or drowsiness, so exercise caution when driving or operating machinery.

What happens if a dose of VILDAMAC TRIO 1000 TAB is missed?

If you miss a dose of VILDAMAC TRIO 1000 TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you frequently forget doses, contact your healthcare provider.

How should VILDAMAC TRIO 1000 TAB be stored?

VILDAMAC TRIO 1000 TAB should be stored in a cool and dry place, ideally below 30°C, and away from direct sunlight. Keep the medicine out of the sight and reach of children. Protect it from light and moisture.