Epilive Er 500

EPILIVE ER 500 by LUPIN LTD is an anti-epileptic medication primarily used in the management of seizures associated with epilepsy. It works by stabilizing electrical activity in the brain to help control and reduce the frequency and intensity of seizures.

Name

• Brand Name: EPILIVE ER 500
• Common Name: Levetiracetam Extended-Release 500 mg

Composition

• Active Ingredient: Levetiracetam 500 mg

Uses

EPILIVE ER 500 is prescribed for the treatment of various types of seizures due to epilepsy.

• Epilepsy: A chronic condition characterized by repeated fits (convulsions).
• Partial-onset seizures: Seizures that affect only one side of the brain but can spread to larger areas.
• Myoclonic seizures: Used in adults and children 12 years and older with juvenile myoclonic epilepsy.
• Primary generalized tonic-clonic seizures: Used in adults and children 6 years and older with idiopathic generalized epilepsy.
• Can be used alone or as adjunct therapy with other anti-epileptic medications to improve seizure control.

Dosage and Administration

• EPILIVE ER 500 should be taken exactly as prescribed by a doctor.
• It can be taken with or without food.
• The tablet should be swallowed whole with a glass of water; it should not be crushed or chewed.
• It is crucial to take the medicine at the same time each day to maintain consistent blood levels and maximize benefit.
• Dosage depends on the individual's condition and response to the medicine and is generally a long-term treatment.
• Do not stop the medication abruptly without consulting a doctor, as this may worsen seizures or cause withdrawal symptoms like anxiety, increased heart rate, and tremors.

Side Effects

While not everyone experiences side effects, some common and serious reactions associated with EPILIVE ER 500 include:

• Common Side Effects: Daytime drowsiness, sleepiness, dizziness, light-headedness, headache, general weakness, fatigue, disturbed sleep, nasal congestion, infection, decreased appetite, nausea, vomiting, diarrhea, indigestion, cough, mood swings, aggression, anxiety, irritation, agitation, and vertigo.
• Serious Side Effects: Severe allergic reactions (anaphylaxis) which can be life-threatening, suicidal thoughts or actions, severe depression, and a decrease in blood cell count. Seek immediate medical attention if you experience rash, itching, trouble breathing, trouble swallowing, or swelling of the hands, face, or mouth.

Precautions

• Allergies: Avoid taking if allergic to Levetiracetam or any other components of the medicine.
• Alcohol: Consumption of alcohol is unsafe as it can increase drowsiness, dizziness, and lack of concentration.
• Pregnancy and Breastfeeding: Generally considered unsafe during pregnancy; consult a doctor. Limited data suggests it may be safe for breastfeeding but monitor the baby for sleepiness and weight gain. Always consult a doctor.
• Medical Conditions: Use with caution in patients with a history of lung disease, liver disease (dosage adjustment may be needed for severe cases), kidney disease (dosage adjustment may be needed), glaucoma, sleep apnea, heart problems (may increase risk of QT interval prolongation), or a history of alcohol or drug abuse.
• Driving and Operating Machinery: EPILIVE ER 500 may cause dizziness, drowsiness, and visual disturbances. Do not drive or operate heavy machinery if you experience these effects.
• Interactions: Inform your doctor about all other medications, including herbal and over-the-counter drugs, to avoid undesirable effects. Taking with other anti-epileptic medications can cause severe drowsiness, breathing problems, coma, and death in some cases.
• Children: Not recommended for use in children under four years of age; use with caution in individuals under 18 or as recommended by a physician under medical supervision for behavioral changes.

Storage

Specific storage instructions were not detailed in the provided search results. It is generally advisable to store medicines according to the instructions on the package insert or as advised by your pharmacist.

EPILIVE ER 500 contains Levetiracetam, an extended-release antiepileptic drug used to manage various types of seizures.

What is EPILIVE ER 500 used for?

EPILIVE ER 500 is primarily used to manage different types of seizures associated with epilepsy. This includes partial-onset seizures, which may be managed alone or in combination with other antiepileptic medications. It also helps control myoclonic seizures in adults and children aged 12 years and older, and primary generalised tonic-clonic seizures in adults and children aged six years and older.

How does EPILIVE ER 500 work?

The active ingredient, Levetiracetam, works by calming overactive nerves in the brain. It binds to specific sites, particularly a protein called synaptic vesicle protein 2A (SV2A), reducing abnormal electrical activity that can trigger seizures and preventing their spread within the brain. This action helps to control seizures without affecting normal neuronal transmission.

What is the usual dosage of EPILIVE ER 500?

For adults and adolescents 12 years of age and older weighing 50 kilograms (kg) or more, the typical starting dose is 1000 mg once daily. The dosage may be adjusted in increments of 1000 mg every 2 weeks, up to a maximum daily dose of 3000 mg. The tablets should be swallowed whole and not crushed or chewed. It can be taken with or without food, but consistency in timing is recommended. Dosage for children under 12 years of age is based on body weight and must be determined by a doctor.

What are the possible side effects of EPILIVE ER 500?

Common side effects can include drowsiness, dizziness, irritability, tiredness, headache, loss of appetite, aggression, anxiety, mood swings, and nasal congestion. More serious, but less common, side effects to report to your doctor immediately include severe skin reactions (like Stevens-Johnson syndrome), allergic reactions (such as rash, itching, swelling of the face, lips, or tongue, or trouble breathing), significant mood and behavior changes (including thoughts of suicide or self-harm), and signs of infection or unusual bleeding/bruising.

Is EPILIVE ER 500 safe during pregnancy or breastfeeding?

During Pregnancy: It is important to continue taking levetiracetam if prescribed for epilepsy during pregnancy, as uncontrolled seizures can harm both the pregnant individual and the baby. However, caution is advised, and it is crucial to discuss potential risks and benefits with your doctor, as the dose may need adjustments, particularly in the third trimester. A high dose of folic acid (5mg a day) is recommended for individuals trying to conceive or who are pregnant while taking levetiracetam. During Breastfeeding: Levetiracetam can pass into breast milk. While often considered safe for the baby, breastfeeding mothers should consult their doctor to discuss the potential risks and benefits. Monitor the baby for any side effects such as drowsiness, vomiting, or not feeding well.

Can EPILIVE ER 500 be taken with other medications?

EPILIVE ER 500 (Levetiracetam) has minimal known severe or serious interactions with other drugs. However, it's important to inform your doctor about all medications, herbs, non-prescription drugs, or dietary supplements you are taking. Possible interactions have been noted with medications such as carbamazepine, colesevelam, probenecid, sevelamer, benzodiazepines, macrogol (a laxative), and methotrexate. Alcohol consumption should be limited or avoided while on this medication, as it can increase the risk of side effects like dizziness and drowsiness.

What precautions should be taken?

Do not stop taking EPILIVE ER 500 abruptly without consulting your doctor, as this can increase the frequency or severity of seizures. It's important to monitor for any changes in mood or behavior, including suicidal thoughts, and report them to your doctor immediately. Use with caution if you have kidney disease, as dosage adjustments may be necessary. Since it can cause drowsiness and dizziness, avoid driving or operating heavy machinery until you know how the medication affects you.

What happens if a dose of EPILIVE ER 500 is missed?

If you miss a dose of EPILIVE ER 500, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should EPILIVE ER 500 be stored?

EPILIVE ER 500 tablets should be kept in a cool, dry place, ideally below 30°C (86°F). Protect it from light and moisture, and always keep this medicine out of the reach and sight of children and pets. Ensure to use the medicine before its expiration date.