Xilingio (m) 10/5/1000mg Tab

XILINGIO (M) 10/5/1000MG TAB by TORRENT PHARMA LTD (DELTA)

Name:

• Common Name: XILINGIO (M) 10/5/1000MG TAB
• Brand Name: Xilingio M

Composition: Each tablet contains a combination of three active ingredients:

• Empagliflozin: 10 mg
• Linagliptin: 5 mg
• Metformin: 1000 mg

Uses: XILINGIO M is primarily prescribed for adults with Type 2 diabetes mellitus to improve glycemic control as an adjunct to diet and exercise. It also helps reduce the risk of cardiovascular death in diabetic patients with established heart disease and may lower hospitalization rates for heart failure. Additionally, it can be used for insulin resistance in polycystic ovary syndrome (PCOS).

Dosage and Administration: This medicine should be taken once daily, usually in the morning, with or without food. The tablet should be swallowed whole and not chewed, crushed, or broken. The specific dosage will be determined by a healthcare professional.

Side Effects: Common side effects include urinary tract infections, nasopharyngitis, upper respiratory tract infections, frequent urination, dizziness, lightheadedness, genital fungal infection, hypoglycemia, cough, constipation, nausea, stuffy or runny nose, sore throat, and diarrhea. Serious but less common side effects can include acute pancreatitis, ketoacidosis, volume depletion, and hypersensitivity reactions.

Precautions:

• Contraindications: Not recommended for patients with Type 1 diabetes, those on dialysis, or with significant renal impairment (eGFR less than 30 mL/min/1.73 m2). Avoid if allergic to empagliflozin, linagliptin, or any excipients.
• Interactions: Concomitant use with insulin or sulfonylureas (e.g., glimepiride) may increase the risk of hypoglycemia. Diuretics can heighten the risk of dehydration and low blood pressure. Certain medicines like cimetidine or trimethoprim may affect metformin clearance.
• Warnings: Inform your doctor about kidney or liver problems, urinary tract infections, or if taking diuretics. Exercise caution in patients over 75 years of age. Discontinue use and seek medical attention if symptoms of acute pancreatitis (severe abdominal pain) or ketoacidosis occur. Avoid alcohol consumption. Inform your doctor before any planned surgeries or contrast imaging tests.

Storage: Store Xilingio M tablets at room temperature, away from moisture, excessive heat, and direct light. Keep the medication out of reach of children and pets, and do not use it beyond its expiration date. Store below 30°C.

Here are the most frequently asked questions about XILINGIO (M) 10/5/1000MG Tablet, along with concise answers:

What is XILINGIO (M) 10/5/1000MG Tablet used for?

XILINGIO (M) 10/5/1000MG Tablet is primarily used to improve blood sugar control in adults with Type 2 Diabetes Mellitus. It helps reduce the risk of heart-related death and other long-term diabetes complications when used alongside a healthy diet and exercise.

How does XILINGIO (M) 10/5/1000MG Tablet work?

This medicine is a combination of three active ingredients: Empagliflozin, Linagliptin, and Metformin Hydrochloride.

• Empagliflozin (an SGLT2 inhibitor) works by blocking a protein in the kidneys that reabsorbs sugar, leading to increased sugar removal from the body through urine.
• Linagliptin (a DPP-4 inhibitor) targets an enzyme that breaks down hormones, helping the pancreas release more insulin and lower sugar levels after meals.
• Metformin (a biguanide) decreases glucose production in the liver and improves the body's sensitivity to insulin. Together, these components work through multiple complementary mechanisms to lower blood glucose levels.

What is the usual dosage for XILINGIO (M) 10/5/1000MG Tablet?

The typical dosage is one tablet once daily, taken at the same time each day, preferably with food. It is crucial to follow your doctor's prescribed dose and duration for this medicine.

What are the possible side effects of XILINGIO (M) 10/5/1000MG Tablet?

Common side effects may include upper respiratory tract infection, constipation, urinary tract infection, headache, stuffy or runny nose, sore throat, diarrhea, nasopharyngitis, genital fungal infection, increased urination, thirst, low blood pressure, and dizziness. If any side effects persist or worsen, consult your doctor.

Is XILINGIO (M) 10/5/1000MG Tablet safe during pregnancy or breastfeeding?

No, XILINGIO (M) 10/5/1000MG Tablet is generally not recommended during pregnancy or while breastfeeding due to potential risks to the baby. Always discuss alternative diabetes treatments with your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can XILINGIO (M) 10/5/1000MG Tablet be taken with other medications?

Yes, it can interact with other medications, especially those affecting kidney function or blood sugar. Inform your doctor about all medicines, supplements, or herbal products you are taking to avoid possible interactions. Specific interactions can occur with diuretics, insulin or sulfonylureas (increasing hypoglycemia risk), certain CYP3A4 inducers, and cationic drugs.

What precautions should be taken while using XILINGIO (M) 10/5/1000MG Tablet?

Do not take this medicine if you have severe kidney disease, certain types of metabolic acidosis, or known allergies to its ingredients. Exercise caution if you are an older adult, have liver problems, or are at risk of dehydration. Avoid excessive alcohol intake, as it can increase the risk of serious side effects like lactic acidosis. Ensure adequate fluid intake and inform your doctor before any planned surgeries or contrast imaging tests, as temporary discontinuation might be necessary. This medication is not for Type 1 diabetes or diabetic ketoacidosis.

What happens if a dose of XILINGIO (M) 10/5/1000MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one. Missing doses can lead to poor blood sugar control.

How should XILINGIO (M) 10/5/1000MG Tablet be stored?

Store XILINGIO (M) 10/5/1000MG Tablet at room temperature, away from moisture, excessive heat, and direct light. Keep it out of reach of children and pets. Do not use the medication past its expiration date.