Midgeo 5 Mg Tablet (10 Tab)

MIDGEO 5 MG TABLET (10 TAB)

MIDGEO 5 MG TABLET is a medication manufactured by CENTAUR PHARMACEUTICALS PVT. LTD., primarily used to manage low blood pressure.

• Name

  • Brand Name: MIDGEO 5 MG TABLET
  • Common Name: Midodrine

• Composition

  • Active Ingredient: Midodrine hydrochloride 5 mg. The active form in the body is desglymidodrine, which stimulates alpha-1 receptors in blood vessels.

• Uses MIDGEO 5 MG TABLET is prescribed to treat low blood pressure (hypotension), particularly:

  • Orthostatic hypotension, a condition where blood pressure drops significantly when a person stands up from a sitting or lying position.
  • Symptoms associated with low blood pressure, such as dizziness, lightheadedness, fainting, blurred vision, and fatigue.
  • Hypotension that may occur during surgical procedures or following injuries.
  • Conditions like Postural Orthostatic Tachycardia Syndrome (POTS) or autonomic dysfunction.

• Dosage and Administration

  • MIDGEO 5 MG TABLET should be taken orally, with or without food, as directed by a doctor.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it.
  • The typical starting dose is 5 mg, taken three times daily, usually in the morning, midday, and late afternoon (before 6 PM), with a gap of at least 3 hours between doses.
  • It is generally recommended to take the medication during the daytime when you are most likely to be in an upright position.
  • The last daily dose should be taken at least 4 hours before bedtime to reduce the risk of supine hypertension (high blood pressure while lying down).
  • Regular monitoring of blood pressure is essential to ensure the medication's effectiveness and to detect any potential issues.

• Side Effects

  • Common Side Effects: Headache, nausea, skin rash, urinary retention (difficulty emptying the bladder), difficulty urinating, flushing (sense of warmth), goosebumps, chills, and supine hypertension.
  • Serious Side Effects: Seek immediate medical attention if you experience chest pain, palpitations (rapid or irregular heartbeat), severe headache, shortness of breath, or blurred vision, as these may indicate serious side effects such as severe hypertension or a slow heart rate.

• Precautions

  • MIDGEO 5 MG TABLET is not recommended for individuals with an allergy to midodrine or any other components, severe heart disease (including heart failure, unusually slow heart rate, or certain heart rhythm disorders), high blood pressure (especially when lying down), severe kidney disease, enlarged prostate, urinary retention, pheochromocytoma, overactive thyroid, diabetes with poor vision, or narrow-angle glaucoma.
  • Caution is advised for patients with a history of prostate disorders, blood circulation problems, or liver conditions.
  • Pregnant and breastfeeding women should consult their doctor, as the medication is generally not recommended during these periods.
  • Avoid alcohol consumption while taking this medicine, as it may worsen dizziness.
  • If you experience dizziness or blurred vision, avoid driving or operating heavy machinery.
  • Do not stop taking the medication abruptly without consulting your doctor, as this can lead to a significant drop in blood pressure.
  • This medication is generally not recommended for children under 18 years of age.

• Storage

  • Store MIDGEO 5 MG TABLET at room temperature (below 30°C) in a cool, dry place.
  • Keep it in its original packaging, protected from light and moisture.
  • Keep out of reach of children and pets.
  • Do not use after the expiry date printed on the package.

What is MIDGEO 5 MG TABLET used for?

MIDGEO 5 MG TABLET is primarily used to treat low blood pressure (hypotension), particularly symptomatic orthostatic hypotension. This condition causes a significant drop in blood pressure when moving from a sitting or lying position to standing, leading to symptoms like dizziness, lightheadedness, fainting, and blurred vision. It can also be used for recurrent reflex syncope and conditions like postural orthostatic tachycardia syndrome (POTS) or autonomic dysfunction.

How does MIDGEO 5 MG TABLET work?

MIDGEO 5 MG TABLET contains midodrine, which is a prodrug. It is converted in the body to its active form, desglymidodrine. Desglymidodrine acts as an alpha-1 adrenergic agonist, stimulating specific receptors on blood vessels. This stimulation causes the arteries and veins to constrict or tighten, which increases the resistance in the circulatory system and helps to elevate blood pressure. This action also prevents blood from pooling excessively in the legs when standing up.

What is the usual dosage for MIDGEO 5 MG TABLET?

The dosage of MIDGEO 5 MG TABLET should be taken exactly as directed by your doctor. A common starting dose is 5 mg, taken three times daily. It is crucial to take this medication during daytime hours when you are mostly upright. The last dose of the day should be taken at least four hours before bedtime to minimize the risk of high blood pressure while lying down (supine hypertension). It should not be taken if you anticipate lying down for an extended period after the dose.

What are the possible side effects of MIDGEO 5 MG TABLET?

Common side effects include supine hypertension (high blood pressure when lying down), paresthesia (tingling sensation, especially on the scalp), pruritus (itching), goosebumps, chills, headache, nausea, rash, urinary urge, urinary retention (difficulty emptying the bladder), and urinary frequency. Less common side effects can include dry mouth, dizziness, drowsiness, trouble sleeping, or leg cramps. If you experience serious side effects like chest pain, palpitations, or severe headaches, seek immediate medical attention.

Is MIDGEO 5 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: MIDGEO 5 MG TABLET is generally not recommended during pregnancy (Pregnancy Category C). It should only be used if the potential benefits outweigh the potential risks to the fetus. You should use proper birth control measures while on this medication and consult your doctor if you are pregnant, planning to become pregnant, or think you might be pregnant.

Breastfeeding: It is not known whether MIDGEO 5 MG TABLET is excreted in human milk. Therefore, caution should be exercised, and you should consult your doctor before breastfeeding while taking this medicine.

Can MIDGEO 5 MG TABLET be taken with other medications?

It is important to inform your doctor about all medications, supplements, and herbal products you are currently taking or plan to take to avoid potential interactions.

• Avoid or use with caution: Medications that also increase blood pressure (such as decongestants, cold remedies, diet aids, phenylephrine, pseudoephedrine, ephedrine, thyroid hormones), MAO inhibitors, linezolid, reserpine, and guanethidine.
• Potential interactions: Alpha-adrenergic blocking agents (like prazosin, terazosin, doxazosin) can antagonize its effects. Digitalis preparations may interact, potentially causing a reduced heart rate. Steroids like fludrocortisone acetate may increase the risk of glaucoma. There may also be interactions with drugs actively secreted by the kidneys, such as metformin, cimetidine, and quinidine.

What precautions should be taken while taking MIDGEO 5 MG TABLET?

Regular monitoring of your blood pressure (lying, sitting, and standing) is essential. To prevent supine hypertension, avoid taking the medication if you plan to lie down for an extended period, and ensure your last dose is at least four hours before bedtime. You may also consider elevating the head of your bed. Do not drive or operate heavy machinery until you know how the medication affects you, as it can cause dizziness or drowsiness. Inform your doctor about any pre-existing conditions such as heart disease, kidney or liver problems, high blood pressure, urinary retention, glaucoma, or diabetes. Do not stop taking the medicine suddenly without consulting your doctor. Alcohol should be avoided as it may worsen side effects.

What happens if a dose of MIDGEO 5 MG TABLET is missed?

If you miss a dose of MIDGEO 5 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should MIDGEO 5 MG TABLET be stored?

Store MIDGEO 5 MG TABLET at room temperature, typically below 30°C, in a cool and dry place. Keep the tablets in their original packaging, protected from moisture and light. Ensure the medication is kept out of sight and reach of children and pets.