Tenglyn M 1000 Tablet

TENGLYN M 1000 Tablet

Tenglyn M 1000 Tablet, manufactured by Zydus Cadila, is an oral antidiabetic medication used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It is often prescribed when diet and exercise alone do not adequately control blood sugar.

• Composition: Each tablet contains Metformin (1000mg) and Teneligliptin (20mg).
• Uses: This medicine is used to treat type 2 diabetes mellitus by improving glycemic control. It works by decreasing glucose production in the liver, lowering intestinal glucose uptake, and increasing the body's insulin levels and sensitivity. It helps prevent serious complications of diabetes such as kidney damage, blindness, heart attacks, and strokes.
• Dosage and Administration: Tenglyn M 1000 Tablet should be taken orally as prescribed by a physician, typically once daily with food to minimize stomach upset. The tablet should be swallowed whole and not crushed, chewed, or broken.
• Side Effects: Common side effects include nausea, vomiting, diarrhea, headache, stomach ache, and respiratory infection. More serious, though rare, side effects can include lactic acidosis and hypoglycemia (low blood sugar), especially when combined with other antidiabetic medicines. Long-term use may also lead to Vitamin B12 deficiency.
• Precautions: Inform your doctor if you have kidney, liver, or heart problems, severe infection, or a history of diabetic ketoacidosis. Alcohol consumption should be avoided as it increases the risk of lactic acidosis. Pregnant or breastfeeding women should consult their doctor before use. It may interact with various medications, including certain anti-diabetics, diuretics, and corticosteroids.
• Storage: Store the medicine in a cool and dry place, below 30°C, protected from direct sunlight and moisture, and out of the sight and reach of children.

TENGLYN M 1000 Tablet by ZYDUS CADILA: Frequently Asked Questions

What is TENGLYN M 1000 Tablet used for?

TENGLYN M 1000 Tablet is primarily used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It is prescribed when diet and exercise alone do not adequately control blood sugar, or when patients have not responded well to metformin alone. By controlling blood sugar, it helps prevent serious complications of diabetes, such as kidney damage, vision impairment, nerve problems, heart attacks, and strokes.

How does TENGLYN M 1000 Tablet work?

TENGLYN M 1000 Tablet contains two active ingredients: Metformin and Teneligliptin.

• Metformin (a biguanide) works by decreasing glucose production in the liver, reducing the absorption of glucose from the intestines, and increasing the body's sensitivity to insulin, thereby improving glucose uptake and utilization.
• Teneligliptin (a dipeptidyl peptidase-4 (DPP-4) inhibitor) works by inhibiting the breakdown of certain natural hormones (incretins like GLP-1 and GIP). This action leads to increased insulin secretion from the pancreas and reduced glucagon levels, especially after meals, which helps to lower both fasting and post-meal blood sugar levels.

What is the usual dosage of TENGLYN M 1000 Tablet?

The dose of TENGLYN M 1000 Tablet will be determined by your doctor based on your condition, blood sugar levels, and any other medications you are taking. It is generally recommended to take this medicine regularly, at the same time each day, usually once daily with a meal to help reduce stomach upset. It should be swallowed whole with a glass of water and not crushed, chewed, or broken. Do not exceed the prescribed dose or stop taking it without consulting your doctor.

What are the possible side effects of TENGLYN M 1000 Tablet?

Common side effects may include nausea, vomiting, diarrhea, headache, stomach ache, abdominal discomfort, flatulence, and loss of appetite. Some patients might also experience respiratory infection or weight gain. A rare but serious side effect is lactic acidosis, which involves a buildup of lactic acid in the blood and requires immediate medical attention. Symptoms can include nausea, vomiting, stomach pain, muscle cramps, weakness, rapid breathing, and feeling cold in arms and legs. Long-term use of metformin (an ingredient) can also lead to Vitamin B12 deficiency.

Is TENGLYN M 1000 Tablet safe during pregnancy or breastfeeding?

TENGLYN M 1000 Tablet should generally be avoided during pregnancy unless specifically recommended by a doctor, as insulin is often preferred for managing pregnancy-related diabetes due to potential risks to the fetus. It is not recommended for use during breastfeeding as it may pass into breast milk and cause unwanted effects in the nursing baby. It is advisable to consult your doctor if you are breastfeeding.

Can TENGLYN M 1000 Tablet be taken with other medications?

Inform your doctor about all medicines you are currently taking, including over-the-counter drugs and herbal supplements, to prevent potential interactions. TENGLYN M 1000 Tablet may interact with certain medications, including:

• Other anti-diabetic medicines (e.g., glimepiride, insulin), which can increase the risk of low blood sugar.
• Cationic medicines like digoxin, ranitidine, and amiloride, and carbonic anhydrase inhibitors like topiramate and acetazolamide, which may increase the risk of lactic acidosis.
• Iodine-containing contrast media (used for X-rays or scans), bronchodilators (e.g., salbutamol), corticosteroids (e.g., hydrocortisone), diuretics (e.g., furosemide), and certain medicines for bacterial or fungal infections.
• Alcohol consumption should be avoided as it increases the risk of lactic acidosis and low blood sugar.

What precautions should be taken while using TENGLYN M 1000 Tablet?

Before taking this medicine, inform your doctor if you have liver, kidney, or heart problems (including irregular heartbeat or heart failure), severe infection, severe trauma, adrenal insufficiency, bowel obstruction, or type 1 diabetes. Regular monitoring of blood sugar levels and kidney function is advised during treatment. Avoid excessive alcohol intake. If you experience symptoms of lactic acidosis (e.g., abdominal pain, muscle cramps, vomiting, severe fatigue, difficulty breathing), seek immediate medical attention.

What happens if a dose of TENGLYN M 1000 Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should TENGLYN M 1000 Tablet be stored?

TENGLYN M 1000 Tablet should be stored in a cool and dry place, away from direct sunlight, moisture, and heat. It should be kept out of the sight and reach of children. Store below 30°C.