Serenace 1.5 Tablet (10 Tab)

SERENACE 1.5 TABLET

SERENACE 1.5 TABLET, manufactured by RPG Life Sciences Limited, is an antipsychotic medication.

Composition

The active ingredient in SERENACE 1.5 TABLET is Haloperidol, at a strength of 1.5 mg.

Uses

SERENACE 1.5 TABLET is prescribed for the management of various mental health conditions:

• Schizophrenia: A brain disorder characterized by delusions, hallucinations, and disturbances in thinking, feelings, and behavior.
• Psychosis and other mood disorders: Conditions involving a distorted perception of reality.
• Tourette Syndrome: A disorder marked by involuntary sounds or repetitive movements (tics).
• Mania: Episodes of overactivity, elation, or irritability, often associated with bipolar disorder.
• Severe behavioral problems: Including agitation, hyperactivity, or aggression in adults and children, especially those with mental illness or retardation.
• Huntington's disease: For the management of associated symptoms.
• It may also be used for nausea and vomiting (e.g., caused by cancer treatment) and for anxiety and pain during surgery (neurolept anesthesia).

Dosage and Administration

SERENACE 1.5 TABLET should be taken exactly as prescribed by your doctor. It can be taken with or without food, preferably at the same time each day to maintain consistent medication levels in the body. Do not stop taking the medicine abruptly, as this can worsen symptoms or lead to withdrawal effects; your doctor may gradually reduce the dose. Typical adult dosage can range from 1 to 15 mg per day, with elderly patients usually requiring 1 to 3 mg per day.

Side Effects

Common side effects may include drowsiness, dizziness, muscle stiffness, tremor, dry mouth, constipation, weight gain, agitation, insomnia, and headache. Serious side effects, though rare, warrant immediate medical attention. These include irregular heartbeat (QT prolongation), tardive dyskinesia (uncontrollable movements), neuroleptic malignant syndrome (fever, muscle stiffness, confusion), severe muscle spasms, convulsions, and allergic reactions (e.g., swelling of the face, difficulty breathing).

Precautions

SERENACE 1.5 TABLET is not recommended if you have an allergy to haloperidol, Parkinson's disease, severe central nervous system depression, or dementia-related psychosis, due to increased risks such as heart failure and death. Caution is advised in patients with heart diseases, prolonged QT intervals, liver or kidney impairment, seizure disorders, hyperthyroidism, glaucoma, or a history of neuroleptic malignant syndrome or tardive dyskinesia.

• Pregnancy and Breastfeeding: Not generally recommended during pregnancy as it may affect the unborn baby. It is also advised against during breastfeeding as it can pass into breast milk.
• Alcohol and Other Medications: Avoid alcohol, as it can intensify drowsiness and other side effects. Inform your doctor about all other medications, especially those for heart problems, depression, anxiety, or Parkinson's disease, as interactions can occur.
• Activities: This medicine may cause drowsiness or dizziness; do not drive or operate heavy machinery until you know how it affects you.

Storage

Store SERENACE 1.5 TABLET in its original packaging, away from light, heat, and moisture. Keep it in a cool, dry place where the temperature stays below 30°C and out of the reach of children.

Here are some frequently asked questions about SERENACE 1.5 TABLET:

What is SERENACE 1.5 Tablet used for?

SERENACE 1.5 Tablet is an antipsychotic medicine primarily used to treat schizophrenia, a mental disorder characterized by delusions, hallucinations, and abnormal thoughts and behavior. It is also prescribed for other psychotic disorders, Tourette's syndrome (a disorder involving repetitive movements or unwanted sounds called tics), acute mania, and severe behavioral problems in adults and children. Additionally, it may be used to manage Huntington's disease.

How does SERENACE 1.5 Tablet work?

SERENACE 1.5 Tablet contains haloperidol, which is a first-generation (typical) antipsychotic. It works by blocking dopamine D2 receptors in the brain, particularly in the mesolimbic and mesocortical systems. This action helps to reduce the overactivity of dopamine, a chemical messenger in the brain that affects thoughts, mood, and behavior, thereby alleviating psychotic symptoms like hallucinations and delusions.

What is the usual dosage for SERENACE 1.5 Tablet?

The dosage of SERENACE 1.5 Tablet is determined by your doctor based on your specific condition, age, and response to treatment. For adults, an initial dose may range from 0.5 to 1.5 tablets (0.75 mg to 2.25 mg of the active ingredient) per day, which can be gradually increased. The standard maintenance dose is often 2 to 4 tablets (3 mg to 6 mg) per day. For elderly patients, a lower dose of 1-3 mg per day is usually sufficient, while children's dosage is typically initiated at 1-3 mg per day with a maintenance dose of 0.05 mg per kg of body weight daily. It is crucial to follow your doctor's instructions precisely and not to adjust the dose without consultation.

What are the possible side effects of SERENACE 1.5 Tablet?

Common side effects can include agitation, difficulty sleeping (insomnia), headache, dizziness, sleepiness, nausea, vomiting, constipation, dry mouth, muscle spasm, tremor, and weight gain. More serious, though rare, side effects can include extrapyramidal symptoms (such as tremors, muscle rigidity, and restlessness), tardive dyskinesia (uncontrollable movements, especially of the face and tongue), neuroleptic malignant syndrome (a severe reaction with high fever, muscle stiffness, and confusion), and irregular heartbeat (QT prolongation). If you experience any severe or persistent side effects, contact your doctor immediately.

Is SERENACE 1.5 Tablet safe during pregnancy or breastfeeding?

SERENACE 1.5 Tablet is generally not recommended for use during pregnancy unless absolutely necessary, as it may affect the unborn baby. If you are pregnant or planning to conceive, you should discuss all potential risks and benefits with your doctor. It is also probably unsafe to use during breastfeeding because the medicine is known to pass into breast milk and could affect the breastfed infant. Your doctor will weigh the benefits against the risks before prescribing it during these periods.

Can SERENACE 1.5 Tablet be taken with other medications?

SERENACE 1.5 Tablet can interact with various medications. It is important to inform your doctor about all other medicines, including over-the-counter drugs, herbal supplements, and vitamins, you are currently taking. It should be used with caution or avoided with medications that can affect heart rhythm (e.g., amiodarone, metoprolol), other antipsychotics, antidepressants (e.g., fluoxetine, paroxetine), anti-seizure medications, and Parkinson's disease medicines (like levodopa) as they may have opposing effects. Alcohol consumption should be avoided as it can increase drowsiness and dizziness.

What precautions should be taken while taking SERENACE 1.5 Tablet?

Several precautions should be observed. Avoid driving or operating heavy machinery if you experience drowsiness, dizziness, or blurred vision. Do not consume alcohol as it can intensify side effects. Inform your doctor if you have pre-existing conditions such as heart disease (including prolonged QT interval), Parkinson's disease, severe central nervous system depression, a history of neuroleptic malignant syndrome, tardive dyskinesia, dementia-related psychosis, liver or kidney problems, epilepsy, or thyroid issues. Do not stop taking the medicine suddenly, even if you feel better, as it can worsen symptoms or lead to withdrawal effects; your doctor will guide you on gradual discontinuation.

What happens if a dose of SERENACE 1.5 Tablet is missed?

If you miss a dose of SERENACE 1.5 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects. If you frequently miss doses or are unsure, consult your doctor or pharmacist.

How should SERENACE 1.5 Tablet be stored?

Store SERENACE 1.5 Tablet in its original packaging, away from light, heat, and moisture, in a cool, dry place where the temperature stays below 30°C. Keep it out of the reach of children. Do not store the medicine outside its pack for extended periods, as it may not keep well.