Polyclav Ds Tab

POLYCLAV DS TAB

POLYCLAV DS TAB is an antibiotic medicine manufactured by Macleods Pharmaceuticals Pvt Ltd, designed to treat a wide range of bacterial infections.

Composition

POLYCLAV DS TAB contains a combination of two active ingredients:

• Amoxicillin (400 mg)
• Clavulanic Acid (57 mg)

Amoxicillin is a penicillin antibiotic that works by inhibiting enzymes essential for bacterial cell wall synthesis, thereby killing the bacteria. Clavulanic Acid is a beta-lactamase inhibitor that prevents bacteria from inactivating Amoxicillin, enhancing its effectiveness against resistant bacteria.

Uses

POLYCLAV DS TABLET is prescribed for managing various bacterial infections, including:

• Middle ear and sinus infections
• Respiratory tract infections (e.g., bronchitis, pneumonia)
• Genital tract infections
• Urinary tract infections (UTIs)
• Skin and soft tissue infections, such as dental infections
• Bone and joint infections
• Septic abortion
• Abdominal infections
• Resistant Tuberculosis (TB)

It is not effective against viral infections like the common cold or flu.

Dosage and Administration

POLYCLAV DS TAB should be taken as advised by a physician.

• Tablets should be swallowed whole with a glass of water; do not crush or chew.
• Dispersible tablets should be dissolved in the specified amount of water and consumed immediately.
• It is generally recommended to take this medicine with food to enhance absorption and minimize stomach upset.
• The exact dose and duration will be determined by the doctor based on age, body weight, and the severity of the infection. Patients should complete the entire course of antibiotics, even if symptoms improve, to prevent bacterial resistance and recurrence of infection.

Side Effects

Common side effects include:

• Diarrhea
• Nausea
• Vomiting
• Thrush (fungal infection in the vagina, skin folds, or mouth)
• Abdominal pain
• Skin rash

More serious but rare side effects can include:

• Inflammation of the liver (hepatitis)
• Jaundice (yellowing of the skin/eyes)
• Anaphylactic reaction
• Steven-Johnson syndrome
• Angioedema
• Erythema
• Hypersensitivity
• Convulsion

Precautions

• Allergy: Contraindicated for individuals with a known allergy to Amoxicillin, Clavulanic Acid, penicillin, or cephalosporin antibiotics.
• Liver/Kidney Impairment: Not recommended for patients with liver problems or jaundice upon taking antibiotics. Use with caution in patients with renal or hepatic impairment.
• Pregnancy and Breastfeeding: Should be used with caution in pregnant and breastfeeding women, only if clearly necessary, as components can pass into breast milk and may cause fungal infections or diarrhea in the infant.
• Driving and Operating Machines: May cause dizziness or make you feel unwell; therefore, caution is advised when driving or operating machinery.
• Drug Interactions: Inform your doctor about all current medications, supplements, or herbal products to avoid potential interactions, especially with blood thinners like warfarin (increased bleeding risk) and methotrexate (increased side effects).

Storage

Store POLYCLAV DS TAB in a cool and dry place, protected from direct sunlight, heat, and moisture, at or below 30°C (or between 10ºC to 25ºC). Keep out of the sight and reach of children.

Here are the frequently asked questions about POLYCLAV DS TAB:

What is POLYCLAV DS TAB used for?

POLYCLAV DS TAB is an antibiotic medication used to treat various bacterial infections. These include infections of the middle ear and sinuses, respiratory tract, genital tract, urinary tract, skin and soft tissues (like dental infections), bone and joint infections, and abdominal infections. It is not effective against viral infections such as the common cold or flu.

How does POLYCLAV DS TAB work?

This medicine contains two active ingredients: Amoxicillin and Clavulanic acid. Amoxicillin is a penicillin-type antibiotic that works by preventing the bacteria from forming their protective cell walls, which ultimately kills the bacteria. Clavulanic acid is a beta-lactamase inhibitor that prevents certain bacteria from inactivating amoxicillin, thereby enhancing its effectiveness against a broader range of bacteria.

What is the usual dosage of POLYCLAV DS TAB?

The dosage of POLYCLAV DS TAB is determined by your doctor based on your age, body weight, the type, and severity of the infection. It should be taken as advised by your physician, usually with a meal to minimize stomach upset. For adults, a common dosage might be one 500 mg/125 mg tablet every 12 hours or one 250 mg/125 mg tablet every 8 hours. For more severe respiratory tract infections, one 875 mg/125 mg tablet every 12 hours or one 500 mg/125 mg tablet every 8 hours may be prescribed. It is crucial to complete the entire course of treatment even if symptoms improve.

What are the possible side effects of POLYCLAV DS TAB?

Common side effects can include diarrhea, thrush (a fungal infection in the vagina, skin folds, or mouth), nausea, and vomiting. Other possible side effects include abdominal pain, skin rash, and allergic reactions. If any side effects worsen or persist, you should contact your doctor immediately.

Is POLYCLAV DS TAB safe during pregnancy or breastfeeding?

POLYCLAV DS TAB should be used with caution during pregnancy and breastfeeding. It is generally advised only if considered necessary by a doctor, and if the potential benefits outweigh the potential risks. Some sources indicate it is generally safe, but a doctor's consultation is essential.

Can POLYCLAV DS TAB be taken with other medications?

POLYCLAV DS TAB can interact with certain medications. Inform your doctor about all medicines, supplements, or herbal products you are currently taking. Notable interactions include:

• Allopurinol and Probenecid (used for gout): May increase the risk of side effects.
• Warfarin (blood thinner): May increase the risk of bleeding.
• Methotrexate (used for certain cancers and rheumatic diseases): May increase side effects.
• Mycophenolate mofetil (used to prevent organ rejection): May affect its efficacy.
• Oral Contraceptives: POLYCLAV DS TAB may reduce the effectiveness of birth control pills. Your doctor may recommend a non-hormonal birth control method while taking this medicine.

What precautions should be taken while taking POLYCLAV DS TAB?

Do not take POLYCLAV DS TAB if you are allergic to amoxicillin, clavulanic acid, penicillin, or any other antibiotic from the cephalosporin class. It is also not recommended if you have a history of liver problems or jaundice associated with antibiotic use. Use with caution if you have kidney disease, liver disease, or glandular fever. Always complete the full prescribed course of antibiotics, even if you feel better, to prevent the infection from returning or becoming resistant. Taking it with food can help reduce stomach upset. If you experience dizziness, avoid driving or operating machinery.

What happens if a dose of POLYCLAV DS TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should POLYCLAV DS TAB be stored?

POLYCLAV DS TAB should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat. The ideal storage temperature is typically below 30°C. Keep it out of the sight and reach of children and pets. Do not use expired or damaged medicine.