Sclerifuma 120 Mg Capsule (10 Cap)

SCLERIFUMA 120 MG CAPSULE

SCLERIFUMA 120 MG CAPSULE is a medication manufactured by SUN PHARMACEUTICAL IND.LTD. It is primarily used for the treatment of multiple sclerosis.

• Name

  • Common Name: Sclerifuma 120 Capsule, Sclerifuma 120mg Dr Capsule
  • Brand Name: SCLERIFUMA (by SUN PHARMACEUTICAL IND.LTD.)

• Composition

  • Active Ingredient: Dimethyl Fumarate (120 mg per capsule)

• Uses SCLERIFUMA 120 MG CAPSULE is used for the treatment of multiple sclerosis (MS) in adults. It is particularly effective for managing:

  • Clinically isolated syndrome (nerve symptom episodes lasting at least 24 hours).
  • Relapsing-remitting multiple sclerosis (RRMS), which involves symptom flare-ups.
  • Active secondary progressive multiple sclerosis (SPMS), a later stage with more frequent relapses. The medication works by decreasing swelling of the nerves, preventing nerve damage, and suppressing the immune system and inflammation that cause nerve damage in MS.

• Dosage and Administration

  • Sclerifuma 120 Capsule should be taken orally as advised by your doctor.
  • It can be taken with or without food, though taking it with food may help reduce side effects like flushing or stomach upset.
  • Swallow the capsule whole with water; do not crush, chew, break, dissolve, or suck the capsule.
  • Your doctor will determine the appropriate dose and duration based on your medical condition.
  • Do not exceed the prescribed dose.

• Side Effects

  • Common Side Effects: Flushing (warmth, redness, itching, or burning sensation of the skin), nausea, vomiting, diarrhea, stomach pain, heartburn, indigestion, abdominal cramps, and skin rash. These usually resolve over time.
  • Serious Side Effects (seek immediate medical attention): Severe allergic reactions (reddening of face/body, swelling of face/lips/tongue, wheezing, difficulty breathing, dizziness), signs of infection (fever, sore throat, rash, severe diarrhea, painful urination, chills, sweats), decreased lymphocyte count, increased liver enzyme levels, and rarely, progressive multifocal leukoencephalopathy (PML) (a rare brain infection).

• Precautions

  • Avoid if allergic to dimethyl fumarate or any other components of the capsule.
  • Use with caution if you have liver problems, as it may increase liver enzyme levels. Your doctor may monitor liver function and blood cell counts.
  • May cause dizziness; avoid driving or operating machinery if you feel dizzy.
  • Can decrease lymphocyte counts (a type of white blood cell), making you more vulnerable to infections. Regular blood tests are recommended.
  • Not recommended for children below 18 years of age due to lack of established safety and efficacy data.
  • Consult your doctor if pregnant, planning a pregnancy, or breastfeeding.
  • Inform your doctor about all other medications, including fumarates, immunosuppressants, kidney-affecting medicines (antibiotics, diuretics, ibuprofen), lithium, and live vaccines, to avoid interactions.
  • Limit alcohol consumption as it may worsen stomach-related side effects.

• Storage

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of the sight and reach of children.
  • Typically stored below 30°C or between 10°C to 25°C.

SCLERIFUMA 120 MG CAPSULE (10 CAP) by SUN PHARMACEUTICAL IND.LTD. is a medication containing Dimethyl Fumarate, primarily used for the treatment of multiple sclerosis.

What is SCLERIFUMA 120 MG CAPSULE used for?

SCLERIFUMA 120 MG CAPSULE is primarily used for the treatment of relapsing forms of multiple sclerosis (MS) in adults and children aged 13 years and older. It is indicated for clinically isolated syndrome, relapsing-remitting MS (RRMS), and active secondary progressive MS (SPMS). It also treats moderate to severe plaque psoriasis.

How does SCLERIFUMA 120 MG CAPSULE work?

This medicine contains Dimethyl Fumarate, which works by reducing inflammation and preventing damage to the nerves caused by the immune system in multiple sclerosis. It modulates immune responses, decreases swelling of the nerves, protects nerve cells, and delays the worsening of the disease. It is considered an Nrf2 activator, enhancing the body's antioxidant defense.

What is the usual dosage for SCLERIFUMA 120 MG CAPSULE?

SCLERIFUMA 120 MG CAPSULE should be taken orally as prescribed by your doctor. The capsules should be swallowed whole with water and not crushed, chewed, dissolved, or sucked. It can be taken with or without food, but taking it with food may help reduce common side effects like stomach upset. The typical starting dose is often 120 mg twice daily, which may be increased to 240 mg twice daily after 7 days, based on tolerance and clinical response.

What are the possible side effects of SCLERIFUMA 120 MG CAPSULE?

Common side effects include flushing (redness, warmth, burning, or itching of the face or body), diarrhea, nausea, vomiting, stomach pain, abdominal pain, indigestion, and rash. More serious, but less common, side effects can include a decrease in white blood cell counts (lymphopenia), which increases the risk of infections, and elevated liver enzyme levels. If side effects persist or worsen, consult your doctor.

Is SCLERIFUMA 120 MG CAPSULE safe during pregnancy or breastfeeding?

SCLERIFUMA 120 MG CAPSULE is generally not recommended for use during pregnancy or while breastfeeding unless considered necessary by your doctor. The risks and benefits should be discussed with a healthcare provider. Effective contraception should be used during treatment and for two months after stopping the medication if you are a woman of childbearing potential.

Can SCLERIFUMA 120 MG CAPSULE be taken with other medications?

Inform your doctor about all medications you are taking, including over-the-counter medicines, supplements, and herbal products, to avoid potential interactions. Be especially cautious if taking other medicines that affect the immune system (e.g., immunosuppressants, chemotherapy, other MS medications), fumaric acid esters (used for psoriasis), certain antibiotics, diuretics, specific painkillers like ibuprofen, or lithium. Live vaccines should also be avoided.

What precautions should be taken with SCLERIFUMA 120 MG CAPSULE?

Before starting treatment, inform your doctor if you have a history of lowered immune response, severe active infection, low white blood cell counts, liver disorders, kidney problems, or stomach/bowel disease. Your doctor will likely conduct blood tests to monitor your blood cell count, and liver and kidney function before and during treatment. Avoid consuming alcohol with this medicine, as it may cause stomach inflammation. If you experience dizziness or fatigue, avoid driving or operating heavy machinery. Do not stop taking the medication abruptly without consulting your doctor.

What happens if a dose of SCLERIFUMA 120 MG CAPSULE is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should SCLERIFUMA 120 MG CAPSULE be stored?

Store SCLERIFUMA 120 MG CAPSULE in a cool and dry place, away from sunlight and moisture. Keep the medicine out of the sight and reach of children. It should generally be stored below 25°C or 30°C.