Monotrate 20 Mg Tablet (10 Tab)

MONOTRATE 20 MG TABLET is a medication manufactured by SUN PHARMA LABORATORIES LTD.

Name

• Brand Name: MONOTRATE 20 MG TABLET
• Common Name: Isosorbide Mononitrate Tablet

Composition

MONOTRATE 20 MG TABLET contains 20 mg of Isosorbide Mononitrate as its active ingredient. This belongs to a class of medications known as nitrate vasodilators.

Uses

MONOTRATE 20 MG TABLET is primarily used to manage and prevent heart-related chest pain, specifically angina pectoris. It works by relaxing and widening blood vessels, which improves blood flow and oxygen supply to the heart muscle, thereby reducing the heart's workload. It is also used in the management of heart failure and coronary artery disease. This medicine is not intended to treat an angina attack that has already begun.

Dosage and Administration

MONOTRATE 20 MG TABLET should be taken orally as directed by a healthcare professional, usually twice a day. It can be taken with or without food. Patients should swallow the tablet whole and not crush or chew it. It is important to take the medicine at the same times each day for optimal benefit, for example, the first dose upon waking and the second dose 7 hours later. Do not stop taking this medicine suddenly without consulting your doctor, as conditions may worsen.

Side Effects

Common side effects include headache, dizziness, lightheadedness, nausea, flushing (sense of warmth), tiredness, and rapid heartbeat. Headaches often indicate the medication is working. More serious, though less common, side effects can include severe hypotension (low blood pressure), fainting, and irregular heartbeat.

Precautions

• Drug Interactions: Concomitant use with phosphodiesterase-5 inhibitors (e.g., sildenafil, tadalafil) is contraindicated as it can cause a severe drop in blood pressure. Alcohol consumption should be avoided as it can increase the risk of side effects like dizziness and low blood pressure.
• Medical Conditions: Caution is advised for individuals with severe anemia, pre-existing low blood pressure (hypotension), liver or kidney problems, glaucoma, or severe hypovolemia.
• Pregnancy and Breastfeeding: Consult a doctor before taking MONOTRATE 20 MG TABLET if pregnant, planning pregnancy, or breastfeeding.
• Children: This medicine is not recommended for children and adolescents under 18 years.

Storage

Store MONOTRATE 20 MG TABLET at room temperature, below 30°C. Protect it from light and moisture, and keep it out of the reach of children and pets. Do not use the medicine after the expiry date.

What is Monotrate 20 mg Tablet used for?

Monotrate 20 mg Tablet is primarily used to prevent heart-related chest pain, also known as angina. It is also used in the management of hypertensive emergency, heart failure, and coronary artery disease. This medication is not intended to treat an angina attack that has already begun.

How does Monotrate 20 mg Tablet work?

Monotrate 20 mg Tablet contains isosorbide mononitrate, which is a nitrate vasodilator. It works by relaxing and widening the blood vessels, particularly those supplying the heart. This improved blood flow increases the oxygen supply to the heart muscle, reducing its workload and easing chest discomfort, thereby preventing angina attacks.

What is the usual dosage of Monotrate 20 mg Tablet?

The dose and frequency of Monotrate 20 mg Tablet are determined by your doctor based on your condition and how well the medicine is working. Typically, it is taken orally, usually twice a day. When taken twice daily, the first dose is often taken in the morning, and the second dose about 7 hours later, to allow for a drug-free interval and prevent tolerance. It can be taken with or without food. Do not take more than the prescribed dose.

What are the possible side effects of Monotrate 20 mg Tablet?

Common side effects include headache, dizziness, flushing (a sense of warmth in the face, ears, neck, and trunk), nausea, and low blood pressure (hypotension). Headaches are often a sign that the medicine is working and usually subside after a few days of treatment. If side effects persist or worsen, consult your doctor.

Is Monotrate 20 mg Tablet safe during pregnancy or breastfeeding?

Monotrate 20 mg Tablet should be used with caution during pregnancy and breastfeeding, and only if absolutely necessary as prescribed by a doctor. It is recommended to discuss all risks and benefits with your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Information regarding its use during breastfeeding is limited, and the medication may cross into breast milk.

Can Monotrate 20 mg Tablet be taken with other medications?

It is crucial to inform your doctor about all medicines, herbals, and supplements you are currently taking to avoid possible interactions. Monotrate 20 mg Tablet should not be taken with phosphodiesterase-5 (PDE-5) inhibitors like sildenafil, tadalafil, or vardenafil (used for erectile dysfunction), as this combination can cause a severe and dangerous drop in blood pressure, leading to fainting or even a heart attack. Caution is also advised with other medications that can lower blood pressure, such as certain medicines for mood disorders, psychosis, migraine, calcium channel blockers, and riociguat.

What precautions should be taken with Monotrate 20 mg Tablet?

Avoid consuming alcohol while taking Monotrate 20 mg Tablet, as it can increase the risk of side effects like dizziness and low blood pressure. This medication can cause dizziness or make you feel sleepy, so exercise caution when driving or operating heavy machinery until you know how it affects you. Inform your doctor if you have conditions such as anemia, low blood pressure, liver disease, kidney issues, glaucoma (increased pressure in the eye), a recent heart attack, head injury, or brain hemorrhage. Do not stop taking the medicine suddenly without consulting your doctor, as this can increase the risk of an angina attack.

What happens if a dose is missed?

If you miss a dose of Monotrate 20 mg Tablet, take it as soon as you remember, provided it is within 12 hours of the scheduled time. However, if it is almost time for your next dose (e.g., more than 12 hours have passed), skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Monotrate 20 mg Tablet be stored?

Monotrate 20 mg Tablet should be stored at room temperature, below 30°C, and protected from light and moisture. Keep it in its original container and out of the reach of children and pets. Do not use the medicine after its expiry date.