Aurogestrone Sr 300mg Tab

AUROGESTRONE SR 300MG TAB

• Name: Aurogestrone SR 300 mg Tablet.

• Composition: Each tablet contains 300 mg of natural micronized Progesterone. This hormone works by replacing estrogen and progesterone levels in the body.

• Uses: Aurogestrone SR 300MG TAB is prescribed for various gynecological and reproductive conditions. It is used in hormone replacement therapy (HRT) to manage menopause symptoms and prevent endometrial hyperplasia (thickened uterus lining). It also treats amenorrhoea (absence of menstrual periods) and menstrual disorders. Additionally, it is indicated for the maintenance of pregnancy, support of the luteal phase during fertility treatments like IVF, prevention of threatened abortion, and reduction of preterm labor risk.

• Dosage and Administration: This medicine is typically taken orally, with or without food. It is often prescribed once daily in the evening or at bedtime. For specific hormone replacement therapy regimens, a daily dose of 300 mg may be divided, with 200 mg taken at bedtime and 100 mg two hours after breakfast for the last 12 to 14 days of estrogen treatment. Do not crush, break, or chew the tablet.

• Side Effects: Common side effects include dizziness, drowsiness, headache, mood changes, diarrhea, vaginal discharge, joint pain, hot flashes, constipation, abdominal pain, nausea, breast pain, bloating, and edema (swelling). More serious, but rare, side effects can include signs of allergic reactions, blood clots, or heart attack.

• Precautions: Inform your doctor if you have allergies to soy or any other medications. Aurogestrone SR 300MG TAB should be avoided if you have breast cancer, unexplained vaginal bleeding, blood clots or clotting disorders, liver disease, porphyria, or cerebral hemorrhage. It is generally advised to consult a doctor if pregnant or breastfeeding. Due to potential dizziness or drowsiness, caution is advised when driving or operating machinery. Special care is needed for patients with diabetes, high blood pressure, migraine, gallstones, asthma, fits, systemic lupus erythematosus, or a history of depression.

• Storage: Store in a cool and dry place away from sunlight. Maintain storage temperatures between 10ºC to 25ºC or below 30ºC. Keep this medicine out of reach and sight of children.

AUROGESTRONE SR 300MG TAB is a sustained-release medication containing progesterone, a natural female hormone. It is primarily used to address issues related to hormonal imbalance and support reproductive health.

What is AUROGESTRONE SR 300MG TAB used for?

AUROGESTRONE SR 300MG TAB is used for several conditions including:

• Hormone Replacement Therapy (HRT): Often used in combination with estrogen to manage menopausal symptoms and prevent the thickening of the uterus lining (endometrial hyperplasia).
• Menstrual Disorders: It helps regulate the menstrual cycle, treat amenorrhoea (absence of menstrual periods), irregular menstruation, and abnormal uterine bleeding.
• Female Infertility and Pregnancy Support: It is prescribed to support the luteal phase during assisted reproductive technologies like IVF, prepare the endometrium for implantation, and help maintain pregnancy, especially in cases of threatened abortion or to prevent preterm labor.
• Prevention of Miscarriage: In some cases, it is recommended for pregnant women with a history of recurrent miscarriages to help maintain the pregnancy.

How does AUROGESTRONE SR 300MG TAB work?

AUROGESTRONE SR 300MG TAB contains progesterone, which works by replacing and supplementing the body's natural progesterone levels. This helps to prepare the uterus for pregnancy by thickening the uterine lining (endometrium), establish and maintain pregnancy, and counteract the effects of estrogen in HRT to prevent excessive endometrial growth.

What is the usual dosage of AUROGESTRONE SR 300MG TAB?

The dosage of AUROGESTRONE SR 300MG TAB is determined by your doctor based on your specific condition. It is typically taken once daily, often in the evening or at bedtime, with or without food. For some conditions, such as HRT, a dose of 300 mg daily might be divided, for example, 200 mg at bedtime and 100 mg two hours after breakfast for the last 12 to 14 days of estrogen treatment per cycle. It should be swallowed whole and not chewed, crushed, or broken.

What are the possible side effects of AUROGESTRONE SR 300MG TAB?

Common side effects may include dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes, constipation, breast pain, irregular vaginal bleeding or spotting, stomach or abdominal cramps, bloating, nausea, vomiting, hair loss, and edema (swelling). Most of these side effects are usually temporary and resolve on their own, but if they persist or worsen, you should consult your doctor.

Is AUROGESTRONE SR 300MG TAB safe during pregnancy or breastfeeding?

The information regarding AUROGESTRONE SR 300MG TAB during pregnancy is mixed. Some sources indicate it is safe if prescribed, with studies showing low or no risk to the developing baby, and that it supports pregnancy. However, other sources advise avoiding it during pregnancy as it may harm the unborn baby or state it is contraindicated. It is crucial to consult your doctor if you are pregnant or planning to become pregnant before taking this medication.

For breastfeeding, AUROGESTRONE SR 300MG TAB is generally considered safe if prescribed, although it may be excreted into human milk. The effect on breastfed infants is unknown, so it is advisable to consult a doctor if you are breastfeeding.

Can AUROGESTRONE SR 300MG TAB be taken with other medications?

You should inform your doctor about all other medications, including over-the-counter drugs, herbal remedies, and supplements you are taking. Progesterone, the active ingredient, can interact with certain medications such as epilepsy medicines (e.g., phenytoin, carbamazepine), some antibiotics (e.g., ampicillins, tetracyclines), HIV medicines (e.g., ritonavir), tuberculosis medicines (e.g., rifampicin), immunosuppressants (e.g., ciclosporin), antifungal medicines (e.g., ketoconazole), spironolactone, diabetes medicines, warfarin, diazepam, tizanidine, and St. John's wort.

What precautions should be taken while taking AUROGESTRONE SR 300MG TAB?

Before taking AUROGESTRONE SR 300MG TAB, inform your doctor if you have any allergies (especially to soy), or pre-existing medical conditions such as breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorders, liver disease, porphyria, cerebral haemorrhage, diabetes, high blood pressure, migraine, gallstones, asthma, fits, systemic lupus erythematosus, or a history of depression or kidney disease. This medicine can cause dizziness or drowsiness, so exercise caution when driving or operating machinery. Alcohol consumption with this medication is not fully understood, so it is best to consult your doctor.

What happens if a dose of AUROGESTRONE SR 300MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should AUROGESTRONE SR 300MG TAB be stored?

AUROGESTRONE SR 300MG TAB should be stored in a cool and dry place, away from direct sunlight, and at a temperature below 30°C. Keep it out of the reach and sight of children and pets.