Metaglez Forte Tablet

METAGLEZ FORTE TABLET

Name:

• Brand Name: Metaglez Forte Tablet
• Manufacturer: Aristo Pharmaceuticals Pvt Ltd

Composition: Each tablet contains two active ingredients:

• Glipizide: 5 mg
• Metformin: 500 mg

Uses: Metaglez Forte Tablet is prescribed for the management of Type 2 Diabetes Mellitus in adults. It is typically used when diet, exercise, and treatment with single antidiabetic agents do not adequately control blood sugar levels. The medicine works by helping to lower high blood sugar, improving the body's sensitivity to insulin, and regulating blood sugar levels after meals.

Dosage and Administration:

• Metaglez Forte Tablet is taken orally, usually once or twice daily.
• It is generally recommended to take the tablet approximately 30 minutes before meals to minimize stomach upset.
• Tablets should be swallowed whole with a glass of water and not crushed, chewed, or broken.
• The exact dosage and duration of treatment are determined by a healthcare professional based on individual blood sugar levels and medical condition.

Side Effects:

• Common Side Effects: Hypoglycemia (low blood sugar), nausea, diarrhea, indigestion, headache, dizziness, blurred vision, weakness, cold sweats, stomach pain, weight gain, edema (swelling), abdominal discomfort, loss of appetite, and metallic taste.
• Serious Side Effects: Though less common, these can include lactic acidosis (symptoms like deep and rapid breathing, severe stomach pain), severe allergic reactions (rash, swelling of face/throat), liver problems (yellowing skin/eyes, dark urine), and vitamin B12 deficiency.

Precautions:

• Metaglez Forte Tablet is contraindicated in patients with Type 1 Diabetes Mellitus, severe heart failure, lactic acidosis, or a known allergy to Glipizide or other sulfonylureas.
• Avoid alcohol consumption as it can increase the risk of lactic acidosis and hypoglycemia.
• Caution is advised for patients with liver, kidney, or heart conditions, hormonal imbalances, malnutrition, or those on an irregular diet.
• The medicine is not recommended during pregnancy or breastfeeding.
• Patients should monitor their blood glucose levels regularly.
• Due to potential dizziness, exercise caution when driving or operating machinery.

Storage: Store Metaglez Forte Tablet in a cool and dry place, protected from moisture, heat, and direct sunlight. Keep the medicine out of the sight and reach of children. Store below 30°C.

METAGLEZ FORTE TABLET: Frequently Asked Questions

What is METAGLEZ FORTE TABLET used for?

METAGLEZ FORTE TABLET is a combination medicine primarily used to manage blood sugar levels in adults with Type 2 Diabetes Mellitus. It is used when diet, exercise, and treatment with a single antidiabetic agent do not provide adequate blood sugar control. This medication is part of a comprehensive diabetes management plan that includes diet and exercise.

How does METAGLEZ FORTE TABLET work?

METAGLEZ FORTE TABLET contains two active ingredients: Glipizide and Metformin. Glipizide, a sulfonylurea, works by stimulating the beta cells of the pancreas to release more insulin and reducing glucose output from the liver. Metformin, a biguanide, primarily decreases glucose production in the liver, reduces the absorption of glucose from the intestines, and improves insulin sensitivity in the body's tissues, allowing insulin to work more effectively.

What is the usual dosage of METAGLEZ FORTE TABLET?

The typical dosage is one tablet, once or twice daily, taken with meals to help minimize gastrointestinal discomfort. It is crucial to follow your doctor's specific instructions regarding the dose and duration of treatment. Your doctor may adjust the dosage based on your blood glucose levels and overall health. Swallow the tablet whole with water; do not crush, chew, or break it.

What are the possible side effects of METAGLEZ FORTE TABLET?

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, and dizziness. More serious, but less common, side effects can include lactic acidosis (symptoms: deep and rapid breathing, severe stomach pain, unusual muscle pain, weakness, cold hands/feet, dizziness), hypoglycemia (low blood sugar with symptoms like sweating, shaking, rapid heartbeat, confusion), and vitamin B12 deficiency. Allergic reactions (rash, itching, swelling) and liver problems (yellowing of skin/eyes, dark urine, persistent nausea) can also occur. Consult your doctor if any side effects persist or worsen.

Is METAGLEZ FORTE TABLET safe during pregnancy or breastfeeding?

METAGLEZ FORTE TABLET is generally not recommended for use during pregnancy as it may cause harm to the unborn baby. Metformin and insulin are typically the preferred treatments for diabetes during pregnancy. There is limited information on its safety during breastfeeding, and it is generally not recommended. Always consult your doctor for advice if you are pregnant, planning a pregnancy, or breastfeeding.

Can METAGLEZ FORTE TABLET be taken with other medications?

METAGLEZ FORTE TABLET can interact with various medications. It's essential to inform your doctor about all medicines, supplements, and herbal products you are currently taking. Some medications that may interact include other antidiabetic drugs (which can increase the risk of hypoglycemia), diuretics, certain pain and inflammation medicines (like NSAIDs), some blood pressure medications, and miconazole. Combining it with alcohol can also increase the risk of hypoglycemia.

What precautions should be taken while using METAGLEZ FORTE TABLET?

Inform your doctor if you have liver or kidney problems, heart failure, or a history of lactic acidosis, as these conditions can increase the risk of serious side effects. Regular monitoring of blood glucose levels is essential. Avoid excessive alcohol consumption. Stay hydrated and discuss any unusual symptoms with your doctor promptly.

What happens if a dose of METAGLEZ FORTE TABLET is missed?

If you miss a dose, take it as soon as you remember, provided it is not almost time for your next scheduled dose. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of low blood sugar.

How should METAGLEZ FORTE TABLET be stored?

Store METAGLEZ FORTE TABLET in a cool, dry place, away from excessive heat, light, and moisture. Keep the medicine in its original container and ensure it is out of the sight and reach of children. Avoid storing medicines in a bathroom cabinet, as the heat and moisture can degrade the medication.