Pramirol Sr 0.52 Mg Tablet (10 Tab)

PRAMIROL SR 0.52 MG TABLET, manufactured by Intas Pharmaceuticals Ltd., is a sustained-release medication primarily used to manage symptoms associated with Parkinson's disease and Restless Leg Syndrome.

Name

• Brand Name: PRAMIROL SR 0.52 MG TABLET
• Common Name: Pramipexole (active ingredient)

Composition

• Each sustained-release tablet contains Pramipexole (0.52 mg).

Uses PRAMIROL SR 0.52 MG TABLET is prescribed for:

• Parkinson's Disease: It helps alleviate symptoms such as tremors, stiffness, slow movements, muscle spasms, and poor muscle control by mimicking the action of dopamine in the brain.
• Restless Leg Syndrome (Willis-Ekbom disease): It manages the uncomfortable urge to move the legs, particularly during rest or sleep, improving sleep quality.

Dosage and Administration Take PRAMIROL SR 0.52 MG TABLET as advised by your doctor, preferably with food and at the same time each day to maintain consistent medication levels. For restless leg syndrome, it is typically taken 2 to 3 hours before bedtime. Swallow the tablet whole; do not crush, break, or chew it. Do not suddenly stop taking this medication without consulting your doctor.

Side Effects

• Common Side Effects: Sleepiness, dizziness, nausea, dry mouth, fatigue, constipation, headache, muscle spasms, and peripheral edema (swelling, especially in legs). Reduced appetite and weight loss may also occur.
• Serious Side Effects: Hallucinations, confusion, aggressive behavior, agitation, abnormal thoughts, changes in vision, uncontrolled movements, and sudden episodes of falling asleep. It may also cause a sudden drop in blood pressure (orthostatic hypotension) upon standing, and impulse control disorders such as increased sex drive, gambling urges, or compulsive spending.

Precautions

• Avoid alcohol consumption, as it can intensify drowsiness and dizziness.
• Exercise caution when driving or operating machinery, as the medicine can cause drowsiness and sudden sleep episodes.
• Rise slowly from sitting or lying down positions to minimize dizziness due to a sudden drop in blood pressure.
• Inform your doctor if you have kidney disease, heart conditions, or a history of psychiatric disorders (e.g., psychosis).
• Not recommended for use in children under 18 years of age.
• Pregnant or breastfeeding women should consult their doctor before use.
• Report any unusual mood changes or compulsive behaviors (e.g., gambling, overeating, increased sexual urges) to your doctor immediately.

Storage Store PRAMIROL SR 0.52 MG TABLET below 25°C or 30°C, protected from light and moisture.

PRAMIROL SR 0.52 MG TABLET, containing the active ingredient Pramipexole, is a medication used to treat certain neurological conditions. Here are some frequently asked questions about this medicine:

What is PRAMIROL SR 0.52 MG TABLET used for?

PRAMIROL SR 0.52 MG TABLET is primarily used to control the symptoms of Parkinson's disease, which include difficulties with movement, muscle control, balance, stiffness, and tremors. It is also used to treat moderate to severe primary restless legs syndrome (RLS), a condition causing discomfort in the legs and an irresistible urge to move them, especially when sitting or lying down.

How does PRAMIROL SR 0.52 MG TABLET work?

This medicine belongs to a class of drugs called dopamine agonists. It works by mimicking the action of dopamine, a natural substance in the brain essential for controlling movement. By stimulating dopamine receptors in the brain, Pramipexole helps to improve muscle control and reduce the symptoms associated with Parkinson's disease and restless legs syndrome.

What is the usual dosage for PRAMIROL SR 0.52 MG TABLET?

For Parkinson's disease, the typical starting dosage for extended-release (SR) tablets is 0.375 mg taken once daily. Your doctor may gradually increase the dose every 5 to 7 days, up to a maximum of 4.5 mg once daily, based on your response and tolerability. For restless legs syndrome, if prescribed as an extended-release tablet, a suggested starting dose is 0.125 mg once daily, usually 2 to 3 hours before bedtime. The dose can be increased every 4 to 7 days, generally not exceeding 0.5 mg once daily. Always follow your doctor's specific instructions regarding your dosage.

What are the possible side effects of PRAMIROL SR 0.52 MG TABLET?

Common side effects can include nausea, dizziness, drowsiness (including sudden sleep attacks), headache, constipation, dry mouth, weakness, unusual body movements (dyskinesia), confusion, abnormal dreams, decreased appetite, and swelling in the lower legs or hands. More serious side effects, though less common, can include hallucinations (seeing or hearing things that are not real), a sudden drop in blood pressure when standing up (orthostatic hypotension), and unusual or compulsive behaviors (such as increased urges to gamble, binge eat, or engage in sexual activity). If you experience any severe or concerning side effects, contact your doctor immediately.

Is PRAMIROL SR 0.52 MG TABLET safe during pregnancy or breastfeeding?

There is not enough adequate data on the use of Pramipexole in pregnant women, and animal studies have shown potential harm to the fetus. Therefore, it should only be used during pregnancy if the potential benefit justifies the potential risk to the unborn baby, and always under the guidance of your doctor. It is not known if Pramipexole passes into human breast milk. As it may inhibit milk production, it's crucial to discuss with your doctor whether to discontinue breastfeeding or the medication.

Can PRAMIROL SR 0.52 MG TABLET be taken with other medications?

PRAMIROL SR 0.52 MG TABLET can interact with other medicines. It's important to inform your doctor about all prescription and over-the-counter medications, vitamins, and herbal supplements you are taking. Alcohol should be avoided as it can increase drowsiness and dizziness. Caution is advised when taking this medicine with sedatives or other medications that cause drowsiness, as this can heighten the risk of sleepiness. Your doctor may need to adjust the dosage of other medications, such as levodopa, when starting Pramipexole.

What precautions should be taken while using PRAMIROL SR 0.52 MG TABLET?

Do not suddenly stop taking PRAMIROL SR 0.52 MG TABLET without consulting your doctor, as this can lead to serious withdrawal symptoms or worsening of your condition. Your doctor will likely advise a gradual reduction in dosage. This medication can cause sudden sleep attacks, even without feeling drowsy, so avoid driving or operating machinery until you know how it affects you. Be cautious when changing positions from sitting or lying down to standing, as it can cause a sudden drop in blood pressure and dizziness. Inform your doctor if you have kidney disease, heart problems, or a history of mental health conditions. This medication is not recommended for individuals under 18 years of age.

What happens if a dose of PRAMIROL SR 0.52 MG TABLET is missed?

If you miss a dose of PRAMIROL SR 0.52 MG TABLET (extended-release), take it as soon as you remember. However, if more than 12 hours have passed since your missed dose, skip that dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should PRAMIROL SR 0.52 MG TABLET be stored?

Store PRAMIROL SR 0.52 MG TABLET at room temperature, generally between 20°C to 25°C (68°F to 77°F), and protect it from light. Keep the medication in a closed container and out of the reach of children. Do not use any outdated medicine.