Empasov S 10/100

EMPASOV S 10/100 by CIPLA LTD

Name

• Brand Name: EMPASOV S 10/100
• Manufacturer: CIPLA LTD

Composition

EMPASOV S 10/100 contains a combination of two active ingredients:

• Empagliflozin (10 mg)
• Sitagliptin (100 mg)

Uses

EMPASOV S 10/100 is prescribed for the management of Type 2 Diabetes Mellitus in adults. It is used to control high blood sugar levels when diet and exercise alone are insufficient. The medication helps improve glycemic control and may reduce the risk of diabetes-related complications such as cardiovascular disease, kidney problems, and nerve damage.

Dosage and Administration

This medicine should be taken as prescribed by your doctor. Typically, it is taken orally, once daily, preferably with or after meals. It is recommended to take the tablet at the same time each day to maintain consistent blood sugar control. Swallow the tablet whole with water; do not chew, crush, or break it.

Side Effects

Common side effects may include:

• Urinary tract infection (UTI)
• Genital fungal infections
• Increased or frequent urination
• Thirst
• Rash or itching
• Headache
• Nausea, vomiting, diarrhea, stomach upset (less common)

Serious side effects are rare but can include low blood sugar (hypoglycemia), dehydration, kidney problems, pancreatitis, or ketoacidosis. Seek immediate medical attention if you experience severe symptoms.

Precautions

• Contraindications: Do not use if allergic to empagliflozin, sitagliptin, or any other ingredients. It is not for Type 1 Diabetes or diabetic ketoacidosis, and is contraindicated in severe kidney or liver disease.
• Warnings: Use with caution in older adults, those at risk of dehydration (e.g., vomiting, diarrhea, fever), or individuals taking diuretics or blood pressure-lowering medications.
• Pregnancy and Breastfeeding: Consult your doctor before use if pregnant, planning a pregnancy, or breastfeeding, as it may be unsafe.
• Alcohol: Avoid excessive alcohol consumption, as it can lower blood sugar and increase the risk of lactic acidosis.
• Driving: May cause dizziness or sleepiness; avoid driving or operating machinery if affected.
• Drug Interactions: Inform your doctor about all other medications, especially insulin, sulfonylureas, diuretics, lithium, and certain antibiotics, as dosage adjustments may be necessary.

Storage

Store EMPASOV S 10/100 in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. Store below 30°C.

EMPASOV S 10/100 by CIPLA LTD: Frequently Asked Questions

What is Empasov S 10/100 used for?

Empasov S 10/100 is used to improve blood sugar control in adults with type 2 diabetes mellitus. It is prescribed as an adjunct to diet and exercise and may also help reduce the risk of diabetes-related complications such as heart disease, kidney problems, and nerve damage.

How does Empasov S 10/100 work?

Empasov S 10/100 contains two active ingredients: Empagliflozin and Sitagliptin. Empagliflozin (10 mg) is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It works by blocking SGLT2 in the kidneys, which leads to increased removal of glucose through urine, thereby lowering blood sugar levels. Sitagliptin (100 mg) is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It increases incretin levels in the body, which helps improve insulin release after meals and reduces glucose production by the liver. The combination of these two medicines provides better blood sugar control.

What is the usual dosage of Empasov S 10/100?

The dosage of Empasov S 10/100 is individualized and should always be taken exactly as prescribed by your doctor. It is typically taken orally once daily, preferably at the same time each day, with or without food. The tablet should be swallowed whole with water and not chewed, crushed, or split.

What are the possible side effects of Empasov S 10/100?

Common side effects of Empasov S 10/100 may include vaginal yeast infections or other genital infections, urinary tract infections (UTIs), increased urination, constipation, rash, itching, upper respiratory tract infections, headache, thirst, nausea, vomiting, diarrhea, stomach upset, dizziness, and fatigue. If any side effects persist or worsen, it's important to consult your doctor.

Is Empasov S 10/100 safe during pregnancy or breastfeeding?

Empasov S 10/100 is generally not recommended during pregnancy as it may cause harm to the unborn baby. It is also probably unsafe to use during breastfeeding, as it is not known whether empagliflozin or sitagliptin passes into human breast milk and animal studies show both components may appear in milk. Always consult your doctor for safer alternatives if you are pregnant, planning a pregnancy, or breastfeeding.

Can Empasov S 10/100 be taken with other medications?

Empasov S 10/100 can interact with certain medications. Concomitant use with diuretics (e.g., furosemide) may increase the risk of dehydration or low blood pressure. Combining it with insulin and sulfonylureas (e.g., glimepiride) may increase the risk of low blood sugar, and your doctor may need to adjust the dose of these medicines. Antibiotics like rifampin may reduce the effectiveness of sitagliptin, and corticosteroids (e.g., prednisone) or sympathomimetics (e.g., epinephrine) may make blood sugar harder to control. Always inform your doctor about all medications, supplements, or herbs you are currently taking to avoid potential interactions.

What precautions should be taken while taking Empasov S 10/100?

Precautions include informing your doctor if you have a history of pancreatitis, kidney impairment, liver impairment, or heart conditions. Empasov S 10/100 is not recommended for patients with severe kidney impairment or those on dialysis, or for individuals with type 1 diabetes or diabetic ketoacidosis. You should avoid excessive alcohol consumption, as it can cause fluctuations in blood sugar levels and increase the risk of dehydration or lactic acidosis. Stay hydrated by drinking sufficient water, and be aware of symptoms of dehydration. Regular monitoring of kidney function and blood sugar levels may be recommended during treatment.

What happens if a dose of Empasov S 10/100 is missed?

If you miss a dose of Empasov S 10/100, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Empasov S 10/100 be stored?

Empasov S 10/100 should be stored in a cool and dry place, away from sunlight. It should be kept out of sight and reach of children. Generally, it should be stored at 10ºC to 25ºC or below 30ºC.