Flutivate E -30gm Cream

FLUTIVATE E -30GM CREAM

Name:

• Common Name: Fluticasone Propionate
• Brand Name: Flutivate E Cream

Composition: Flutivate E Cream contains Fluticasone Propionate 0.05% w/w as the active ingredient. It is a potent corticosteroid. The cream also includes excipients such as methylparaben, propylparaben, and imidurea.

Uses: Flutivate E Cream is prescribed for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. It effectively treats various skin conditions, including:

• Eczema (atopic dermatitis, nummular dermatitis)
• Psoriasis
• Contact dermatitis
• Lichen planus and lupus It works by reducing swelling, redness, and itching associated with these conditions.

Dosage and Administration: Flutivate E Cream is for external use only. A thin layer should be applied gently to the clean and dry affected area, typically once or twice daily, or as directed by a healthcare professional, for up to 4 weeks. Hands should be washed before and after application, unless the hands are the treated area. Avoid contact with eyes, nose, or mouth. Do not cover the treated area with airtight dressings unless specifically advised by a doctor.

Side Effects: Common side effects may include:

• Itching
• Burning sensation
• Skin irritation or redness (erythema)
• Urticaria (skin rash)
• Dryness
• Skin thinning (atrophy), striae, or pigmentation changes with prolonged use. Most of these effects are temporary. If symptoms persist or worsen, consult a doctor.

Precautions:

• Do not use if allergic to Fluticasone Propionate or any other ingredients.
• Avoid application to broken skin, open wounds, the face (prolonged use can cause thinning), eyes, or eyelids.
• Use with caution in children; it is generally not recommended for infants under 3 months, and children under 12 years should be supervised by a pediatrician, as they are more susceptible to systemic side effects.
• Pregnant or breastfeeding individuals should consult their doctor before use. If used during lactation, avoid applying to the breasts.
• Discontinuation should be gradual to prevent rebound of skin conditions.
• Inform your doctor about any other medications being taken, especially potent CYP3A4 inhibitors (e.g., ketoconazole, ritonavir), which may increase systemic absorption.
• Avoid smoking or going near a naked flame due to the risk of severe burns from treated fabric.

Storage: Store in a cool and dry place below 25°C or below 30°C, away from direct sunlight and moisture. Do not freeze. Keep out of sight and reach of children.

What is Flutivate E Cream used for?

Flutivate E Cream is a potent topical corticosteroid primarily used to treat a variety of inflammatory and itchy (pruritic) skin conditions. These include eczema, various forms of dermatitis (such as allergic contact dermatitis), psoriasis, and lupus. It is also indicated for reducing the risk of relapse in chronic recurrent atopic dermatitis.

How does Flutivate E Cream work?

Flutivate E Cream contains Fluticasone Propionate, which belongs to a class of medicines called corticosteroids. It works by decreasing inflammation, redness, and itching in the skin. This is achieved by inhibiting the production of certain chemical messengers in the body, such as prostaglandins and leukotrienes, which are responsible for causing inflammatory symptoms.

What is the usual dosage for Flutivate E Cream?

Typically, a thin layer of Flutivate E Cream should be applied to the affected skin area once or twice a day. The cream should be gently rubbed in. Treatment duration usually does not exceed 4 weeks, or as directed by your healthcare provider. For children over 3 months, the smallest effective amount should be used for the shortest possible duration under medical guidance. Once the condition improves, your doctor may advise reducing the frequency of application.

What are the possible side effects of Flutivate E Cream?

Common side effects at the application site include local skin burning, itching, irritation, redness, and dryness. Prolonged or excessive use can lead to skin thinning (atrophy), stretch marks (striae), changes in pigmentation, and increased hair growth (hypertrichosis). Rarely, especially with long-term use over large body areas, or with occlusive dressings, systemic effects like hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome features, and increased blood sugar levels can occur.

Is Flutivate E Cream safe during pregnancy or breastfeeding?

During pregnancy, Flutivate E Cream should only be used if the potential benefit to the mother justifies the possible risk to the fetus. The minimum quantity should be used for the shortest duration. If you are breastfeeding, consult your doctor before using this medicine. If applied to the breasts, ensure it is thoroughly washed off before feeding to prevent accidental ingestion by the infant.

Can Flutivate E Cream be used with other medications?

Generally, interactions with other topical products are not expected unless advised by your doctor. However, if applied over large areas or for prolonged periods, systemic absorption can occur. This might potentially diminish the efficacy of insulin and other antidiabetic agents by increasing blood glucose levels. Medications that inhibit CYP3A4 enzymes (e.g., ritonavir, cobicistat) can increase the systemic exposure of corticosteroids. Always inform your doctor about all medications, herbal products, and supplements you are currently using.

What precautions should be taken when using Flutivate E Cream?

Flutivate E Cream is for external use only. Avoid contact with eyes, mouth, open wounds, or broken skin. Wash your hands thoroughly after applying the cream, unless your hands are the treated area. Do not cover the treated area with bandages or airtight dressings unless specifically instructed by your doctor, as this can increase systemic absorption and the risk of side effects. Avoid long-term continuous use, particularly on the face, as it can lead to skin thinning. It is not recommended for infants under 3 months of age, and in children, it should be used with caution, applying the minimum necessary amount for the shortest duration under medical supervision. Do not use this cream for acne, perianal or genital itching, or on infected skin, as it may worsen these conditions. Consult your doctor if your symptoms do not improve within 2 to 4 weeks or if they worsen. The cream contains imidurea, which releases traces of formaldehyde, a known allergen.

What happens if a dose of Flutivate E Cream is missed?

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double amount to make up for a missed dose.

How should Flutivate E Cream be stored?

Flutivate E Cream should be stored at room temperature, typically below 25°C or 30°C, away from moisture and direct sunlight. It is important to keep this medicine out of reach of children and pets. Do not freeze the cream.